Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine Pharmacology

Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

About Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

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Mechanism of Action of Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

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Pharmacokinets of Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

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Onset of Action for Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

N/A

Duration of Action for Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

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Half Life of Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

N/A

Side Effects of Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

N/A

Contra-indications of Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

N/A

Special Precautions while taking Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

N/A

Pregnancy Related Information

Contraindicated. Since Chlorpheniramine Maleate is contraindicated in pregnancy the combination generic cannot be used in pregnancy.

Old Age Related Information

N/A

Breast Feeding Related Information

Contraindicated. Since Chlorpheniramine Maleate is contraindicated in breast feeding mother the combination generic cannot be used in lactation

Children Related Information

N/A

Indications for Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

1.Cough due to allergy
2.Cold

Interactions for Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

N/A

Typical Dosage for Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

1 - 2 teaspoonful to be taken 3 - 4 times daily

Schedule of Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

N/A

Storage Requirements for Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

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Effects of Missed Dosage of Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

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Effects of Overdose of Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine

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Ammonium chloride

About Ammonium chloride

Ammonium compound, Acidifier,Expectorant.

Mechanism of Action of Ammonium chloride

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Pharmacokinets of Ammonium chloride

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Onset of Action for Ammonium chloride

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Duration of Action for Ammonium chloride

N/A

Half Life of Ammonium chloride

N/A

Side Effects of Ammonium chloride

N/A

Contra-indications of Ammonium chloride

N/A

Special Precautions while taking Ammonium chloride

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Ammonium chloride

N/A

Interactions for Ammonium chloride

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Typical Dosage for Ammonium chloride

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Schedule of Ammonium chloride

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Storage Requirements for Ammonium chloride

N/A

Effects of Missed Dosage of Ammonium chloride

N/A

Effects of Overdose of Ammonium chloride

N/A

Sodium citrate

About Sodium citrate

Sodium compound,citrates, Urinary alkalinizing agent, a directly acing expectorant.

Mechanism of Action of Sodium citrate

Sodium citrate is an alkalinizing agent which is used to make the urine more alkaline (less acidic).It prevents certain kinds of kidney stones and also relieve discomfort in mild urinary tract infections such as cystitis. Sodium citrate also makes the blood more alkaline in certain conditions. Sodium citrate is a directly acing expectorant which increases bronchial secretion by salt action.

Pharmacokinets of Sodium citrate

Absorption: Administered orally, Metabolism: Metabolized in to sodium bicarbonate, Excretion: Excreted through urine.

Onset of Action for Sodium citrate

N/A

Duration of Action for Sodium citrate

N/A

Half Life of Sodium citrate

N/A

Side Effects of Sodium citrate

1. Polyuria
2. Hypernatremia
3. Metabolic alkalosis
4. Diarrhea
5. Loose bowel movements
6. Allergic reactions (rare)
7. Chest pain (rare)
8. Shortness of breath (rare)

Contra-indications of Sodium citrate

Hypersensitivity to the drug

Special Precautions while taking Sodium citrate

1. Renal impairment
2. Edema
3. Hypertension
4. Patients on a sodium restricted diet
5. Along with other medication
6. Addison`s disease
7. Type 2 diabetes mellitus
8. Chronic Diarrhea
9. Cardiac diseases
10. Toxemia of pregnancy
11. Urinary tract infections

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

May be used

Indications for Sodium citrate

1. Expectorant
2. Kidney stones
3. Cystitis
4. Gout
5. Urine and blood alkaliniser
6. Symptomatic treatment of nausea and vomiting

Interactions for Sodium citrate

N/A

Typical Dosage for Sodium citrate

Oral:
Expectorant: 0.3 to 1g
As alkaliniser: Dosage individualized and varies in different combinations Symptomatic treatment of nausea and vomiting: Use 5%Sodium citrate in the following doses:
Adults: 2 to3 g; 3 to 4 times daily.
Children (up to 3 months): 0.05 g;
Children (3 to 6 months): 0.1 g;
Children (6 to 12 months): 0.25 g;
Children (2 to 3 years): 0.30 g;
Children (4 to 7 years): 0.50 g;
Children (8 to 14 years): 1 to 2 g; 3 to 4 times daily

Schedule of Sodium citrate

N/A

Storage Requirements for Sodium citrate

Store in a cool dry area in a tightly closed container. Protect from direct light, heat, and moisture

Effects of Missed Dosage of Sodium citrate

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Sodium citrate

Provide symptomatic treatment and supportive measures.

Chlorpheniramine Maleate

About Chlorpheniramine Maleate

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Mechanism of Action of Chlorpheniramine Maleate

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Pharmacokinets of Chlorpheniramine Maleate

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Onset of Action for Chlorpheniramine Maleate

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Duration of Action for Chlorpheniramine Maleate

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Half Life of Chlorpheniramine Maleate

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Side Effects of Chlorpheniramine Maleate

N/A

Contra-indications of Chlorpheniramine Maleate

First Generation alkylamine H1 Antagonist, Antihistamine.

Special Precautions while taking Chlorpheniramine Maleate

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Pregnancy Related Information

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Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

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Indications for Chlorpheniramine Maleate

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Interactions for Chlorpheniramine Maleate

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Typical Dosage for Chlorpheniramine Maleate

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Schedule of Chlorpheniramine Maleate

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Storage Requirements for Chlorpheniramine Maleate

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Effects of Missed Dosage of Chlorpheniramine Maleate

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Effects of Overdose of Chlorpheniramine Maleate

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Ephedrine

About Ephedrine

Alpha/Beta Adrenergic Agonist , Sympathomimetic amine, Stimulant, vasopressor(parenteral), bronchodilator.

Mechanism of Action of Ephedrine

Ephedrine is a mixed acting sympathomimetic drug which mainly acting indirectly but also has some direct action on alpha and beta adrenergic receptors. It causes release of nor-epinephrine from it`s storage sites and stimulates alpha and beta adrenergic receptors. It relaxes bronchial smooth muscle by stimulating beta-2 adrenergic receptors and thus causes increased vital capacity, relief of mild bronchospasm, improved air exchange and decreased residual volume. Ephedrine produces cardiac stimulation with increased systolic and diastolic pressure when nor-epinephrine stores aren`t depleted. It produces positive inotropic effects with low doses through action on beta-1 receptors in heart. It causes vasodilatation through beta-2 receptors and vasoconstriction through alpha adrenergic receptors. Presser effects results from vasoconstriction, cardiac stimulation, and increased cardiac output. It produces nasal decongestant action by stimulating alpha receptors in blood vessels of nasal mucosa and causing vasoconstriction and nasal decongestion.

Pharmacokinets of Ephedrine

Absorption: Well absorbed after Oral, S.C., or I.M. administration.
Distribution: Widely distributed throughout the body
Metabolism: Slowly metabolized in liver by oxidative deamination, demethylation, aromatic hydroxylation and conjugation.
Excretion: Excreted mainly through urine as unchanged drug.

Onset of Action for Ephedrine

Oral: 15 to 60 minutes
I.V.: 5minutes
I.M., S.C.: 10 to 20 minutes

Duration of Action for Ephedrine

Oral: 3 to 5 hours
I.V.: 60 minutes
I.M.: S.C.: 30 to 60 minutes

Half Life of Ephedrine

N/A

Side Effects of Ephedrine

1. Arrhythmias
2. Palpitations
3. Tachycardia
4. Hypertension
5. Precordial pain
6. Insomnia
7. Nervousness
8. Headahe
9. Dizziness
10. Confusion
11. Euphoria
12. Delirium
13. Mucosal irritation
14. Dry nose and throat
15. Nausea
16. Vomiting
17. Anorexia
18. Urine retention
19. Painful urination
20. Muscle weakness
21. Diaphoresis.

Contra-indications of Ephedrine

1. Hypersensitivity to the drug or other sympathomimetics
2. Severe coronary artery disease
3. Porphyria
4. Arrhythmias
5. Angina pectoris
6. Susstatial organic heart disease
7. Cardiovascular diseases
8. Angle closure glaucoma
9. Psychoneurosis
10. In those taking MAO inhibitors

Special Precautions while taking Ephedrine

1. Hypertension
2. Hyperthyroidism
3. Nervous or excitable states
4. Diabetes
5. Prostatic hyperplasia
6. Diabetes

Pregnancy Related Information

Contraindicated

Old Age Related Information

Use with caution

Breast Feeding Related Information

Contraindicated

Children Related Information

Use with caution

Indications for Ephedrine

1. As nasal decongestant
2. As bronchodilator
3. Acute severe bronchospasm
4. Hypotension
5. Enuresis

Interactions for Ephedrine

N/A

Typical Dosage for Ephedrine

Oral:
Adults:
As bronchodilator or nasal decongestant:12.5 to 50mg at every 3 to 4 hours; as required. Do not exceed 150mg in 24 hours.
Orthostatic hypotension: 25mg 1 to 4 times daily as required.
Children:
Above 12 years:12.5 to 50mg at every 3 to 4 hours; as required. Do not exceed 150mg in 24 hours.
Age 6 to 12: 6.25 to 12.5mg every four hours. Do not exceed 75mg in 24 hours.
Children over 2 years: 2 to 3mg/kg/day in 4 to 6 divided doses.
Orthostatic hypotension: 3mg/kg/day divided in to 4 to 6 doses.
Enuresis: 25 to 50mg at bed time.
Nasal spray:
As nasal decongestant:
Adults and children over 12 years: 2 to 3 sprays to each nostril; not more than every four hours.
Children (age 6 to 12): 1 to 2 sprays to each nostril; not more than every four hours.
I.M., S.C., or I.V.:
Acute severe bronchospasm: 12.5 to 25mg I.M., S.C., or I.V.
Hypotension:
Adults: 25 to 50mg S.C. or I.M., or 10 to 25mg as slow I.V. bolus. A second I.M. dose of 50mg or I.V. dose of 25mg is administered if required. Repeat I.V. doses in 5 to 10minutes if required.
Maximum dose: 150mg/day.
Children: 3mg/kg/day S.C. or I.V. divided in to 4 to 6 doses

Schedule of Ephedrine

N/A

Storage Requirements for Ephedrine

Store at controlled room temperature at a range of 15 to 30 degree C. in a well closed container. Protect from light.

Effects of Missed Dosage of Ephedrine

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Ephedrine

Provide supportive treatment and symptomatic measures. If patient is conscious induce emesis and reduce absorption by administration of activated charcoal. Perform gastric lavage if required. Maintain airway and blood pressure and closely monitor vital signs. Do not administer vasopressors. Beta blockers such as propranolol are used to treat arrhythmias. Use cardio selective beta blockers in asthmatic patients. Treat hypertension with Phentolamine, Seizures with paraldehyde or Diazepam, Pyrexia with seizures.

Home Delivery for Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine in Your City

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Ammonium chloride + Sodium citrate + Chlorpheniramine Maleate + Ephedrine is a generic medicine name and there are several brands available for it. Some of the brands for ammonium chloride + sodium citrate + chlorpheniramine maleate + ephedrine might be better known than ammonium chloride + sodium citrate + chlorpheniramine maleate + ephedrine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have ammonium chloride + sodium citrate + chlorpheniramine maleate + ephedrine in stock, you can ask for one of the branded alternatives for ammonium chloride + sodium citrate + chlorpheniramine maleate + ephedrine.