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- Pharmacology For Dextromethorphan + Ammonium chloride + Bromhexine
Dextromethorphan + Ammonium chloride + Bromhexine Pharmacology
Dextromethorphan + Ammonium chloride + Bromhexine
About Dextromethorphan + Ammonium chloride + BromhexineN/AMechanism of Action of Dextromethorphan + Ammonium chloride + BromhexineN/APharmacokinets of Dextromethorphan + Ammonium chloride + BromhexineN/AOnset of Action for Dextromethorphan + Ammonium chloride + BromhexineN/ADuration of Action for Dextromethorphan + Ammonium chloride + BromhexineN/AHalf Life of Dextromethorphan + Ammonium chloride + BromhexineN/ASide Effects of Dextromethorphan + Ammonium chloride + BromhexineN/AContra-indications of Dextromethorphan + Ammonium chloride + BromhexineN/ASpecial Precautions while taking Dextromethorphan + Ammonium chloride + BromhexineN/APregnancy Related InformationContraindicated; since Dextromethorphan and Bromhexine are contraindicated in pregnancy, the combination generic cannot be used in pregnancy.Old Age Related InformationN/ABreast Feeding Related InformationContraindicated; since Dextromethorphan and Bromhexine are contraindicated in lactation, the combination generic cannot be used in breast feeding mother.Children Related InformationN/AIndications for Dextromethorphan + Ammonium chloride + Bromhexine1.Cough
2.Bronchitis
3.Pulmonary congestion
4.Condition where retention of sputum is a problem
Interactions for Dextromethorphan + Ammonium chloride + BromhexineN/ATypical Dosage for Dextromethorphan + Ammonium chloride + BromhexineAdult: 2 teaspoonful to be taken 3 - 4 times daily
Children:1/ 2 - 1 teaspoonful to be taken 3 - 4 times daily
Schedule of Dextromethorphan + Ammonium chloride + BromhexineN/AStorage Requirements for Dextromethorphan + Ammonium chloride + BromhexineN/AEffects of Missed Dosage of Dextromethorphan + Ammonium chloride + BromhexineN/AEffects of Overdose of Dextromethorphan + Ammonium chloride + BromhexineN/ADextromethorphan
About DextromethorphanA synthetic morphine (((dextrorotatory methyl ether of Levorphanol))) derivative,A synthetic narcotic antitussive.Mechanism of Action of DextromethorphanDextromethorphan hydrobromide is a selective antitussive which raises threshold of cough centre and suppresses the cough reflex by direct action on the cough centre in the medulla. It does not depress mucociliary function of the airway mucosa and is also devoid of constipating and addicting actions. (((Its antitussive action is not exerted through opioid receptors)))Pharmacokinets of DextromethorphanAbsorption: Well absorbed orally, Metabolism: Extensively metabolized by liver, Excretion: Excreted primarily through urine as metabolites; about 7 to 10% is excreted through faeces.Onset of Action for DextromethorphanBelow ? an hourDuration of Action for Dextromethorphan3 to 6 hoursHalf Life of Dextromethorphan11 hoursSide Effects of Dextromethorphan1. Dizziness
2. Nausea
3. Vomiting
4. Stomach pain
5. Drowsiness
6. Ataxia.Contra-indications of DextromethorphanPatients currently taking MAO inhibitors or within two weeks of discontinuing MAO inhibitors.Special Precautions while taking Dextromethorphan1. Atopic children
2. Sedated or deliberate patients
3. Those patients confined to the supine position
4. Patients sensitive to aspirin
Pregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationMay be used
Children below 2 years: Syrup, tablets, or lozenges are contraindicated
Indications for DextromethorphanChronic nonproductive cough.Interactions for DextromethorphanN/ATypical Dosage for DextromethorphanOral:
Chronic nonproductive cough:
Adults and children above 12 years: 10 to 20mg every 4 hours; or 30mg three to four times daily.
Maximum dose: 120mg daily.
Children (((age 6 to 12))): 5 to 10mg every four hours
Maximum dose: 60mg daily
Children (((age 2 to 6))): 2.5 to 5mg every four hours.
Maximum dose: 30mg daily.
Schedule of DextromethorphanN/AStorage Requirements for DextromethorphanStore at room temperature in a well closed light resistant container. Protect from excess heat and moisture. Keep out of reach of children.Effects of Missed Dosage of DextromethorphanTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of DextromethorphanRemove drug from the body by administration of activated charcoal and provide symptomatic treatment and supportive measures.Ammonium chloride
About Ammonium chlorideAmmonium compound, Acidifier,Expectorant.Mechanism of Action of Ammonium chlorideN/APharmacokinets of Ammonium chlorideN/AOnset of Action for Ammonium chlorideN/ADuration of Action for Ammonium chlorideN/AHalf Life of Ammonium chlorideN/ASide Effects of Ammonium chlorideN/AContra-indications of Ammonium chlorideN/ASpecial Precautions while taking Ammonium chlorideN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Ammonium chlorideN/AInteractions for Ammonium chlorideN/ATypical Dosage for Ammonium chlorideN/ASchedule of Ammonium chlorideN/AStorage Requirements for Ammonium chlorideN/AEffects of Missed Dosage of Ammonium chlorideN/AEffects of Overdose of Ammonium chlorideN/ABromhexine
About BromhexineMucolytic (secretolytic)Mechanism of Action of BromhexineBromhexine hydrochloride acts as a mucokinetic and mucolytic agent. It decreases mucus viscosity by altering its structure. It depolymerises mucopolysaccharides directly as well as by liberating lysosomal enzymes and network of fibres in tenacious sputum is broken. It induces thin copious bronchial secretion.Pharmacokinets of BromhexineAbsorption: Bromhexine hydrochloride is rapidly absorbed from the gastrointestinal tract and bioavailability is about 20%. Distribution: It is widely distributed to body tissues in a highly protein bound form; Bromhexine crosses the blood brain barrier and small amounts cross the placenta, Metabolism: It undergoes extensive first-pass metabolism in the liver. Excretion: It is excreted primarily in the urine mainly as metabolites.Onset of Action for BromhexineN/ADuration of Action for BromhexineN/AHalf Life of Bromhexine12hours.Side Effects of Bromhexine1 Rhinorrhoea
2 Lacrimations
3.Allergic reactions
4.Gastric irritation.Contra-indications of BromhexineHypersensitivity to the drug.Special Precautions while taking Bromhexine1. Hepatic impairment
2. Renal impairment
3. Gastric and duodenal ulcer
4. Convulsive disorders
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Bromhexine1. As Expectorant and mucolytic
2. Conditions associated with production of viscid mucous
3. Bronchitis
4. Pharyngitis
5. Laryngitis
6. Rhinitis
7. Sinusitis
8. Asthmatic bronchitis
9. Mucous bronchiectasis
10.Chronic Pneumonia.Interactions for BromhexineN/ATypical Dosage for BromhexineOral: 8mg thrice daily.
Children (5 to 10 years): 4mg thrice daily
Children (1 to 5 years): 4mg twice daily.
Schedule of BromhexineHStorage Requirements for BromhexineStore in a cool dry place and protect from light. Keep out of reach of children.Effects of Missed Dosage of BromhexineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of BromhexineProvide symptomatic treatment and supportive measures.Home Delivery for Dextromethorphan + Ammonium chloride + Bromhexine in Your City
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Dextromethorphan + Ammonium chloride + Bromhexine is a generic medicine name and there are several brands available for it. Some of the brands for dextromethorphan + ammonium chloride + bromhexine might be better known than dextromethorphan + ammonium chloride + bromhexine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dextromethorphan + ammonium chloride + bromhexine in stock, you can ask for one of the branded alternatives for dextromethorphan + ammonium chloride + bromhexine.