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- Pharmacology For Zinc + Sulfadiazine
Zinc + Sulfadiazine Pharmacology
Zinc + Sulfadiazine
About Zinc + SulfadiazineN/AMechanism of Action of Zinc + SulfadiazineN/APharmacokinets of Zinc + SulfadiazineN/AOnset of Action for Zinc + SulfadiazineN/ADuration of Action for Zinc + SulfadiazineN/AHalf Life of Zinc + SulfadiazineN/ASide Effects of Zinc + SulfadiazineN/AContra-indications of Zinc + SulfadiazineN/ASpecial Precautions while taking Zinc + SulfadiazineN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Zinc + SulfadiazineN/AInteractions for Zinc + SulfadiazineN/ATypical Dosage for Zinc + SulfadiazineN/ASchedule of Zinc + SulfadiazineN/AStorage Requirements for Zinc + SulfadiazineN/AEffects of Missed Dosage of Zinc + SulfadiazineN/AEffects of Overdose of Zinc + SulfadiazineN/AZinc
About ZincTrance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.Mechanism of Action of ZincZinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.Pharmacokinets of ZincAbsorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.Onset of Action for ZincN/ADuration of Action for ZincN/AHalf Life of ZincN/ASide Effects of Zinc1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes
Contra-indications of ZincN/ASpecial Precautions while taking Zinc1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction
Pregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Zinc1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia
Interactions for ZincFluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.
Typical Dosage for ZincAdults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of ZincN/AStorage Requirements for ZincStore at a temperature below 30 degree CEffects of Missed Dosage of ZincTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ZincProvide symptomatic treatment and supportive measuresSulfadiazine
About SulfadiazineShort acting sulfonamide, Antibiotic.Mechanism of Action of SulfadiazineSulfadiazine is a short-acting sulfonamide. Sulfadiazine is a structural analogs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of dihydrofolic acid, a compound that bacteria must be able to make in order to survive for the synthesis of folic acid, an important metabolite in DNA synthesis. It is usually given with Pyrimethamine in the treatment of Chloroquine resistant Plasmodium falciparum in a fixed dose formulation.
Sulfadiazine has also been used with other sulfonamides, particularly Sulfamerazine and Sulfadimidine, to reduce the problems of low solubility in urine.
Pharmacokinets of SulfadiazinePharmaco Kinetic
Absorption: Sulfadiazine is readily absorbed from the gastrointestinal tract.
Distribution: About 20 - 55% of the drug is distributed in protein bound form.It penetrates into the CSF. Excretion: Drug and its metabolites are excreted in urine.
Onset of Action for SulfadiazineN/ADuration of Action for SulfadiazineN/AHalf Life of Sulfadiazine10 hoursSide Effects of Sulfadiazine1.Loss of appetite
2.Diarrhoea.
3.Headache
4.Fatigue
5.Dizziness
6.Difficulty sleeping
7.Allergic reactions
Contra-indications of SulfadiazineN/ASpecial Precautions while taking SulfadiazineN/APregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationContraindicatedChildren Related InformationN/AIndications for Sulfadiazine1.Nocardiosis
2.Lymphogranuloma venereum
3.Rheumatic fever in penicillin-allergic patients
4.ToxoplasmosisInteractions for SulfadiazineN/ATypical Dosage for SulfadiazineAdult: Initial doses of 2 to 4 g, followed by up to 6 g daily in divided doses.
Children:
Initial dose: 75 mg/kg, then 150 mg/kg daily in divided doses to a maximum of 6 g daily. Infants less than 2 months:
Congenital toxoplasmosis: 50 mg/kg twice daily for 12 months
Toxoplasmosis (Immuno compromised patients): 4 to 6 g daily in 4 divided doses for at least 6 weeks, followed by 2 to 4 g daily
For the prophylaxis of rheumatic fever: 500mg - 1 g daily
Schedule of SulfadiazineN/AStorage Requirements for SulfadiazineStore at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light.Effects of Missed Dosage of SulfadiazineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of SulfadiazineGive symptomatic and supportive treatment. Induce gastric lavage.Home Delivery for Zinc + Sulfadiazine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including zinc + sulfadiazine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for zinc + sulfadiazine and other medicines and health products. Home delivery services for zinc + sulfadiazine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take zinc + sulfadiazine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for zinc + sulfadiazine before they complete the sale. You can get this information while placing the order for zinc + sulfadiazine with the pharmacy.
Zinc + Sulfadiazine is a generic medicine name and there are several brands available for it. Some of the brands for zinc + sulfadiazine might be better known than zinc + sulfadiazine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have zinc + sulfadiazine in stock, you can ask for one of the branded alternatives for zinc + sulfadiazine.