Ipratropium Bromide (Nasal) Pharmacology

Ipratropium Bromide (Nasal)

About Ipratropium Bromide (Nasal)
Anticholinergic, Muscarinic antagonist,Tropane derivative, Decongestant
Mechanism of Action of Ipratropium Bromide (Nasal)
Ipratropium bromide selectively acts on bronchial muscle without altering volume or consistency of respiratory secretions. It inhibits vagally mediated reflexes by antagonizing the actions of acetylcholine. It prevents the acetylcholine mediated increase in intracellular cyclic GMP concentration that results from interaction of acetylcholine with muscarinic receptor on bronchial smooth muscle. It does not depress the muco-ciliary clearance by bronchial epithelium. It blocks the cholinergic constrictor tone and acts primarily in the larger airways. Ipratropium helps to relieve a runny nose due to seasonal allergies or non-allergic seasonal. Ipratropium nasal sprays do not relieve nasal congestion or sneezing.
Pharmacokinets of Ipratropium Bromide (Nasal)
Absorption: Not readily absorbed in to systemic circulation.
Onset of Action for Ipratropium Bromide (Nasal)
N/A
Duration of Action for Ipratropium Bromide (Nasal)
N/A
Half Life of Ipratropium Bromide (Nasal)
N/A
Side Effects of Ipratropium Bromide (Nasal)
1.Cough
2.Dry mouth
3.Metallic taste in mouth
4.Dry nose
5.Irritation
6.Itching in the nose
7.Stuffy nose
Contra-indications of Ipratropium Bromide (Nasal)
1. Hypersensitivity to Ipratropium bromide
Special Precautions while taking Ipratropium Bromide (Nasal)
1. Angle closure glaucoma
2. Prostatic hyperplasia
3. Bladder neck obstruction
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Ipratropium Bromide (Nasal)
1. Rhinorrhea
2. Common cold
3. Allergic rhinitis
4. Perennial rhinitis
Interactions for Ipratropium Bromide (Nasal)
N/A
Typical Dosage for Ipratropium Bromide (Nasal)
Dosage individualized based on patients requirements.
Rhinorrhea, Allergic rhinitis, Perennial rhinitis:
Nasal spray (0.03%):
Adults and children over 12years: 2 sprays (42mcg) per nostril two to three times daily.
Nasal spray (0.06%):Rhinorrhea associated with common cold:
Adults and children over 12years: 2 sprays (84mcg) per nostril three to four times daily.
Children (5 to 12): 2 sprays (84mcg) per nostril three times daily

Schedule of Ipratropium Bromide (Nasal)
N/A
Storage Requirements for Ipratropium Bromide (Nasal)
Store at controlled room temperature at a range of 15 to 30 degree C. Protect from Direct heat, light, and moisture. Avoid freezing. Keep out of reach of children. Shake well before use.
Effects of Missed Dosage of Ipratropium Bromide (Nasal)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Ipratropium Bromide (Nasal)
It is not readily absorbed in to systemic circulation so acute overdose is unlikely to occur. Provide symptomatic treatment and supportive measures.

Home Delivery for Ipratropium Bromide (Nasal) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including ipratropium bromide (nasal).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for ipratropium bromide (nasal) and other medicines and health products. Home delivery services for ipratropium bromide (nasal) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take ipratropium bromide (nasal) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for ipratropium bromide (nasal) before they complete the sale. You can get this information while placing the order for ipratropium bromide (nasal) with the pharmacy.

Ipratropium Bromide (Nasal) is a generic medicine name and there are several brands available for it. Some of the brands for ipratropium bromide (nasal) might be better known than ipratropium bromide (nasal) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have ipratropium bromide (nasal) in stock, you can ask for one of the branded alternatives for ipratropium bromide (nasal).