MAGNESIUM SULPHATE Pharmacology

MAGNESIUM SULPHATE

About MAGNESIUM SULPHATE
Saline Laxative, Osmotically acting
Mechanism of Action of MAGNESIUM SULPHATE
Oral: Magnesium sulfate increases peristaltic activity by causing osmotic retention of fluids, thus resulting in bowel evacuation. Parenteral: Magnesium sulfate decreases levels of acetylcholine in motor nerve terminals. It also acts on the myocardium by decreasing the rate of SA node impulse formation and prolonging the conduction time
Pharmacokinets of MAGNESIUM SULPHATE
Absorption: Absorbed after oral and IM administration
Distribution: Crosses the placenta and small amounts enter the breastmilk. Protein-binding: 25-30%
Excretion: Via urine (absorbed fraction); Via faeces (unabsorbed fraction)
Onset of Action for MAGNESIUM SULPHATE
Oral: 1 to 2hr, IM: 1 hr, IV: Immediate
Duration of Action for MAGNESIUM SULPHATE
IM: 3 to 4 hr, IV: 30 minute
Half Life of MAGNESIUM SULPHATE
N/A
Side Effects of MAGNESIUM SULPHATE
1.Diarrhoea
2.Bradycardia
3.CNS depression
4.Hypocalcemia
5.Nausea
6.Vomiting
Contra-indications of MAGNESIUM SULPHATE
1.Myocardial Infarction
2.Heart Block
3.Renal Impairment
Special Precautions while taking MAGNESIUM SULPHATE
1.Renal impairment
2.Myasthaenia gravis
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for MAGNESIUM SULPHATE
1.Seizures in pregnancy
2.Hypomagnesaemia
3.Heart attack
4.Asthma
5.Constipation
Interactions for MAGNESIUM SULPHATE
Oral: Decreases absorption of tetracyclines and biphosphonates
Additive neuromuscular blocking effects with aminoglycosides, digitalis glycosides
Additive effects with nifedipine and CNS depressants
Typical Dosage for MAGNESIUM SULPHATE
1.5 gm 6 hourly IV or IM. Dosage is adjusted according to individual requirements and the response to treatment
Schedule of MAGNESIUM SULPHATE
N/A
Storage Requirements for MAGNESIUM SULPHATE
Store in a well closed container, below 40 degree celcius. Protect from sunlight and moisture. Keep out of the reach of children
Effects of Missed Dosage of MAGNESIUM SULPHATE
N/A
Effects of Overdose of MAGNESIUM SULPHATE
N/A

Home Delivery for MAGNESIUM SULPHATE in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including magnesium sulphate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for magnesium sulphate and other medicines and health products. Home delivery services for magnesium sulphate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take magnesium sulphate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for magnesium sulphate before they complete the sale. You can get this information while placing the order for magnesium sulphate with the pharmacy.

MAGNESIUM SULPHATE is a generic medicine name and there are several brands available for it. Some of the brands for magnesium sulphate might be better known than magnesium sulphate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have magnesium sulphate in stock, you can ask for one of the branded alternatives for magnesium sulphate.