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- Pharmacology For Metaxalone + Diclofenac Potassium
Metaxalone + Diclofenac Potassium Pharmacology
Metaxalone + Diclofenac Potassium
About Metaxalone + Diclofenac PotassiumN/AMechanism of Action of Metaxalone + Diclofenac PotassiumN/APharmacokinets of Metaxalone + Diclofenac PotassiumN/AOnset of Action for Metaxalone + Diclofenac PotassiumN/ADuration of Action for Metaxalone + Diclofenac PotassiumN/AHalf Life of Metaxalone + Diclofenac PotassiumN/ASide Effects of Metaxalone + Diclofenac PotassiumN/AContra-indications of Metaxalone + Diclofenac PotassiumN/ASpecial Precautions while taking Metaxalone + Diclofenac PotassiumN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with caution;>12yrs:ContraindicatedIndications for Metaxalone + Diclofenac PotassiumFor acute painful musculoskeletal condition in adultInteractions for Metaxalone + Diclofenac PotassiumN/ATypical Dosage for Metaxalone + Diclofenac PotassiumN/ASchedule of Metaxalone + Diclofenac PotassiumN/AStorage Requirements for Metaxalone + Diclofenac PotassiumN/AEffects of Missed Dosage of Metaxalone + Diclofenac PotassiumN/AEffects of Overdose of Metaxalone + Diclofenac PotassiumN/AMetaxalone
About MetaxaloneCentrally acting Skeletal Muscle Relaxant, Muscle Relaxant.Mechanism of Action of MetaxaloneN/APharmacokinets of MetaxaloneN/AOnset of Action for MetaxaloneN/ADuration of Action for MetaxaloneN/AHalf Life of MetaxaloneN/ASide Effects of MetaxaloneN/AContra-indications of MetaxaloneN/ASpecial Precautions while taking MetaxaloneN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for MetaxaloneN/AInteractions for MetaxaloneN/ATypical Dosage for MetaxaloneN/ASchedule of MetaxaloneN/AStorage Requirements for MetaxaloneN/AEffects of Missed Dosage of MetaxaloneN/AEffects of Overdose of MetaxaloneN/ADiclofenac Potassium
About Diclofenac PotassiumNSAID, anti-inflammatory ,antipyretic and analgesic.Mechanism of Action of Diclofenac PotassiumDiclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (((PGs))). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake.Pharmacokinets of Diclofenac PotassiumAbsorption: Diclofenac potassium is rapidly absorbed after oral administration. It undergoes first pass metabolism. Distribution: It is distributed in highly protein bound form. Metabolism: Diclofenac potassium is metabolised in the liver to mainly 4 hydroxy Diclofenac. Excretion: Drug and metabolites are primarily excreted in urine and some amount in the bile.Onset of Action for Diclofenac PotassiumAnalgesic action: with in 60 minutes and Antirheumatic action with in 2 weeksDuration of Action for Diclofenac Potassium12hoursHalf Life of Diclofenac Potassium1-2 hoursSide Effects of Diclofenac Potassium1.Nausea
2.Vomiting
3.Anorexia
4.Diarrhoea
5.Gastrointestinal bleeding
6.Abdominal distress
7.Constipation
8.Flatulence
9.Ulceration of the stomach or intestine
10.Dyspepsia
11.Headache
12.Dizziness
13.Rash
Contra-indications of Diclofenac Potassium1.Hypersensitivity to Diclofenac and other Non steroidal anti inflammatory drugs(((NSAID)))
2.Peptic ulcer
3.Asthma
Special Precautions while taking Diclofenac Potassium1.Hepatic impairment
2.Renal impairment
3.Hypertension
4.Blood clotting disorders
5.Gastrointestinal diseases
6.Proctitis
7.Asthma
8.Cautioned against driving, operating or activities requiring concentration
9.Avoid alcohol
10.Heart failure
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with caution
CHILDREN below 14: contraindicatedIndications for Diclofenac Potassium1.Rheumatoid arthritis
2.Ankylosing spondylitis
3.Acute gout
4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints
5.Osteoarthritis
6.For the relief of pain and inflammation in dental minor surgery and orthopedic
7.Dysmenorrhoea
8.Migraine
Interactions for Diclofenac PotassiumN/ATypical Dosage for Diclofenac PotassiumAdult: 100 - 150 mg / day in 2 - 3 divided doses.
For the relief of pain, Migraine, Dysmenorrhoea: 150 mg / day in 3 divided doses.
Osteoarthritis: 50 mg 2 - 3 times daily
Rheumatoid arthritis: 150 - 200 mg / day in 3 - 4 divided doses.
Schedule of Diclofenac PotassiumHStorage Requirements for Diclofenac PotassiumStore Diclofenac potassium at room temperature in a tightly closed light resistant container.Effects of Missed Dosage of Diclofenac PotassiumTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Diclofenac PotassiumGive supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing emesis. Absorption of the drug can be reduced by administration of activated charcoal.Home Delivery for Metaxalone + Diclofenac Potassium in Your City
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Metaxalone + Diclofenac Potassium is a generic medicine name and there are several brands available for it. Some of the brands for metaxalone + diclofenac potassium might be better known than metaxalone + diclofenac potassium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have metaxalone + diclofenac potassium in stock, you can ask for one of the branded alternatives for metaxalone + diclofenac potassium.