Betamethasone Dipropionate + Zinc Sulphate Pharmacology

Betamethasone Dipropionate + Zinc Sulphate

About Betamethasone Dipropionate + Zinc Sulphate
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Mechanism of Action of Betamethasone Dipropionate + Zinc Sulphate
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Pharmacokinets of Betamethasone Dipropionate + Zinc Sulphate
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Onset of Action for Betamethasone Dipropionate + Zinc Sulphate
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Duration of Action for Betamethasone Dipropionate + Zinc Sulphate
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Half Life of Betamethasone Dipropionate + Zinc Sulphate
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Side Effects of Betamethasone Dipropionate + Zinc Sulphate
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Contra-indications of Betamethasone Dipropionate + Zinc Sulphate
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Special Precautions while taking Betamethasone Dipropionate + Zinc Sulphate
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Pregnancy Related Information
Use with caution
Old Age Related Information
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Breast Feeding Related Information
Use with caution
Children Related Information
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Indications for Betamethasone Dipropionate + Zinc Sulphate
Corticosteriod-responsive dermatoses.
Interactions for Betamethasone Dipropionate + Zinc Sulphate
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Typical Dosage for Betamethasone Dipropionate + Zinc Sulphate
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Schedule of Betamethasone Dipropionate + Zinc Sulphate
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Storage Requirements for Betamethasone Dipropionate + Zinc Sulphate
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Effects of Missed Dosage of Betamethasone Dipropionate + Zinc Sulphate
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Effects of Overdose of Betamethasone Dipropionate + Zinc Sulphate
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Betamethasone dipropionate

About Betamethasone dipropionate
A synthetic glucocorticoid, anti-inflammatory.
Mechanism of Action of Betamethasone dipropionate
The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-alpha, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemotaxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of Betamethasone dipropionate
Absorption: It is absorbed in to the systemic circulation and the amount is depending on the potency, amount applied and the nature of the skin at the site of application. Absorption increases at the site of skin damage, inflammation or occlusion.

Onset of Action for Betamethasone dipropionate
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Duration of Action for Betamethasone dipropionate
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Half Life of Betamethasone dipropionate
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Side Effects of Betamethasone dipropionate
1.Thinning of the skin
2.Loss of elasticity
3.Increased hair growth
4.Acne at the site of application
5.Mild depigmentation
6.Rosacea
Contra-indications of Betamethasone dipropionate
1.Hypersensitivity to Betamethasone
2.Untreated bacterial virus or fungal infections
3.Acne vulgaris
4.Peri-oral dermatitis
5.Tuberculosis of the skin
6.Varicose ulcers
7.Skin lesions caused by infections with herpes simplex vaccinia or varicella viruses. fungi (e.g. Candida Tinea) or bacteria (e.g. impetigo)
8.Discoid lupus Erythematosus
Special Precautions while taking Betamethasone dipropionate
1.Avoid contact with eyes
2.For external use only
3.Prolonged use
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: contraindicated
Indications for Betamethasone dipropionate
1.Eczema
2.Psoriasis
3.Contact dermatitis
4.Anal and vulval Pruritis
5.Inflammation of the skin
Interactions for Betamethasone dipropionate
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Typical Dosage for Betamethasone dipropionate
Apply thinly 1 -2 times daily.
Schedule of Betamethasone dipropionate
H
Storage Requirements for Betamethasone dipropionate
Store at room temperature in a well closed; light resistant container. Protect from excess heat and moisture. Keep out of reach of children.
Effects of Missed Dosage of Betamethasone dipropionate
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Betamethasone dipropionate
Provide symptomatic treatment and supportive measures.

Zinc Sulphate

About Zinc Sulphate
Zinc compound, An astringent , Adjunctive treatment of Wilson?s disease.
Mechanism of Action of Zinc Sulphate
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Pharmacokinets of Zinc Sulphate
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Onset of Action for Zinc Sulphate
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Duration of Action for Zinc Sulphate
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Half Life of Zinc Sulphate
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Side Effects of Zinc Sulphate
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Contra-indications of Zinc Sulphate
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Special Precautions while taking Zinc Sulphate
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Zinc Sulphate
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Interactions for Zinc Sulphate
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Typical Dosage for Zinc Sulphate
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Schedule of Zinc Sulphate
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Storage Requirements for Zinc Sulphate
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Effects of Missed Dosage of Zinc Sulphate
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Effects of Overdose of Zinc Sulphate
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Home Delivery for Betamethasone Dipropionate + Zinc Sulphate in Your City

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Betamethasone Dipropionate + Zinc Sulphate is a generic medicine name and there are several brands available for it. Some of the brands for betamethasone dipropionate + zinc sulphate might be better known than betamethasone dipropionate + zinc sulphate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have betamethasone dipropionate + zinc sulphate in stock, you can ask for one of the branded alternatives for betamethasone dipropionate + zinc sulphate.