Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein Pharmacology

Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

About Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Mechanism of Action of Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Pharmacokinets of Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Onset of Action for Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Duration of Action for Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Half Life of Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Side Effects of Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Contra-indications of Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Special Precautions while taking Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Pregnancy Related Information

Use with caution

Old Age Related Information

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Breast Feeding Related Information

Use with caution

Children Related Information

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Indications for Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

1.Diabetic and peripheral neuropathies
2.Nutritional supplement

Interactions for Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Typical Dosage for Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Schedule of Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Storage Requirements for Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Effects of Missed Dosage of Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Effects of Overdose of Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein

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Alpha-Lipoic acid

About Alpha-Lipoic acid

Naturally occurring dithiol compound , antioxidant, Agent for neuropathies.

Mechanism of Action of Alpha-Lipoic acid

Alpha-lipoic acid and its reduced metabolite, Dihydrolipoic acid (DHLA), form a redox couple and may scavenge a wide range of reactive oxygen species. Alpha-lipoic acid has been found to decrease urinary isoprostanes, O-LDL and plasma protein carbonyls, markers of oxidative stress. Further, alpha-lipoic acid and its redox couple DHLA have been found to have antioxidant activity in aqueous, as well as in lipophilic regions, and in extra cellular and intracellular environments. Alpha-lipoic acid participates in the recycling of other important biologic antioxidants, such as vitamins E and C, Ubiquinone and glutathione.
Both alpha-lipoic acid and DHLA can scavenge hydroxyl radicals, the nitric oxide radical, peroxynitrite, hydrogen peroxide and hypochlorite. Alpha-lipoic acid may scavenge singlet oxygen, and DHLA may scavenge super oxide and peroxyl reactive oxygen species.

Pharmacokinets of Alpha-Lipoic acid

Absorption: Alpha-lipoic acid is absorbed from the small intestine. The natural R-entantiomer is more readily absorbed than the L-entantiomer and is the more active form.
Distribution:It is distributed to the liver via the portal circulation and to various tissues in the body via the systemic circulation. . Alpha-lipoic acid readily crosses the blood-brain barrier. It is found, after its distribution to the various body tissues, intracellularly, intramitochondrialy and extracellularly.Metabolism: Alpha-lipoic acid is metabolized to its reduced form, dihydrolipoic acid (DHLA), by mitochondrial lipoamide dehydrogenase enzyme. DHLA, together with lipoic acid, form a redox couple. It is also metabolized to lipoamide, which functions as the lipoic acid cofactor in the multienzyme complexes that catalyze the oxidative decarboxylations of pyruvate and alpha-ketoglutarate. Alpha-lipoic acid may be metabolized to dithiol octanoic acid, which can undergo catabolism.

Onset of Action for Alpha-Lipoic acid

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Duration of Action for Alpha-Lipoic acid

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Half Life of Alpha-Lipoic acid

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Side Effects of Alpha-Lipoic acid

1.Nausea
2.Vomiting

Contra-indications of Alpha-Lipoic acid

1.Contraindicated during radiotherapy

Special Precautions while taking Alpha-Lipoic acid

Patient with diabetes and problems with glucose intolerance

Pregnancy Related Information

Use with caution

Old Age Related Information

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Breast Feeding Related Information

Use with caution

Children Related Information

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Indications for Alpha-Lipoic acid

1.Diabetic neuropathy
2.It may help prevent the oxidation of LDL cholesterol and may be protective, generally, against oxidative stress and, specifically, against atherosclerosis, ischemia-reperfusion injury and various radiologic and chemical toxins.
3.It may also be useful in some inborn metabolic disorders

Interactions for Alpha-Lipoic acid

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Typical Dosage for Alpha-Lipoic acid

Adult: up to 600 milligrams daily
Diabetic neuropathy: 300 milligrams daily taken in divided doses.

Schedule of Alpha-Lipoic acid

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Storage Requirements for Alpha-Lipoic acid

Store at room temperature away from moisture and heat.Keep out of the reach of children. Keep the medicine from freezing. Do not refrigerate.

Effects of Missed Dosage of Alpha-Lipoic acid

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.

Effects of Overdose of Alpha-Lipoic acid

Give supportive measures and symptomatic treatment.

About

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Special Precautions while taking

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Pregnancy Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for

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Zinc

About Zinc

Trance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.

Mechanism of Action of Zinc

Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.

Pharmacokinets of Zinc

Absorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.

Onset of Action for Zinc

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Duration of Action for Zinc

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Half Life of Zinc

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Side Effects of Zinc

1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes

Contra-indications of Zinc

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Special Precautions while taking Zinc

1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction

Pregnancy Related Information

Use with caution

Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Zinc

1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia

Interactions for Zinc

Fluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.

Typical Dosage for Zinc

Adults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.

Schedule of Zinc

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Storage Requirements for Zinc

Store at a temperature below 30 degree C

Effects of Missed Dosage of Zinc

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Zinc

Provide symptomatic treatment and supportive measures

Chromium

About Chromium

Chromium is by far the most pivotal nutrient involved in sugar metabolism. Trivalent chromium is a part of glucose tolerance factor, an essential activator of insulin mediated reactions. Chromium improves insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increases in insulin sensitivity. Thus it helps to maintain normal glucose metabolism and peripheral nerve function. A number of clinical studies have been conducted which show that chromium is an effective therapy for both Type I and Type II diabetes. Except for supplementation, there is no good way to rebuild the body?s stockpile of chromium.
Deficiency symptoms: Impaired glucose tolerance, peripheral neuropathy, ataxia, confusion.
Over dosage symptoms: In normal therapeutic doses side effects have not been reported except occasional insomnia. In the event of over dosage - nausea, vomiting, GI ulcers, renal/hepatic damage, convulsion, coma may occur.

Mechanism of Action of Chromium

Chromium picolinate acts by influencing carbohydrate metabolism. It stimulates Insulin mediated reactions and improves glucose tolerance. Chromium picolinate helps to improve; insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increase in insulin sensitivity. Thus it maintains normal glucose metabolism and peripheral nerve functions. It improves carbohydrate metabolism, increases energy and helps to control diabetes. It also helps to control weight.

Pharmacokinets of Chromium

Absorption: Well absorbed orally, Distribution: Widely distributed in the body in especially in to liver, kidney, bone, and spleen; normal plasma level is 1 to 5mcg/l. Excretion: Excreted mainly through urine.

Onset of Action for Chromium

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Duration of Action for Chromium

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Half Life of Chromium

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Side Effects of Chromium

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Contra-indications of Chromium

1. Hypersensitivity to the drug.

Special Precautions while taking Chromium

1. Prolonged therapy with the drug
2.Hypoglycaemia
3.In patients with Type II diabetes mellitus use of chromium picolinate is only under the direct medical supervision
4.Renal impairment
5.Hepatic impairment

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

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Indications for Chromium

1.Type I diabetes mellitus
2.Type II diabetes mellitus
3.Obesity.

Interactions for Chromium

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Typical Dosage for Chromium

Oral: 200 mcg daily; increases up to 1mg daily if required.

Schedule of Chromium

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Storage Requirements for Chromium

Store in a well closed container at a cool dry place.

Effects of Missed Dosage of Chromium

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Chromium

Give supportive measures and symptomatic treatment.

Inositol

About Inositol

Vitamin-like substance,neutraceutical.

Mechanism of Action of Inositol

Inositol is a molecule that is an important structural component of cell membranes and molecules that serve as messengers within the body .Inositol might balance certain chemicals in the body to possibly help with conditions such as panic disorder, depression, obsessive-compulsive disorder, and polycystic ovary syndrome.

Pharmacokinets of Inositol

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Onset of Action for Inositol

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Duration of Action for Inositol

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Half Life of Inositol

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Side Effects of Inositol

1.Nausea
2.Tiredness
3.Headache
4.Dizziness

Contra-indications of Inositol

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Special Precautions while taking Inositol

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Inositol

1.Panic disorder. Inositol shows some promise for controlling panic attacks and the fear of public places or open spaces (agoraphobia). One study found that inositol is as effective as a prescription medication
2.Obsessive-compulsive disorder (OCD). There is some evidence that people with OCD who receive inositol by mouth for 6 weeks experience significant improvement
3.An ovary disorder known as polycystic ovary syndrome (PCOS). Taking a particular form of inositol (isomer D-chiro-inositol) by mouth seems to lower triglyceride and testosterone levels, modestly decrease blood pressure, and promote ovulation in obese women with polycystic ovary syndrome.
4.Problems breathing in premature infants known as ?acute respiratory distress syndrome,? when given intravenously (by IV).
5.Psoriasis brought on or made worse by lithium drug therapy. Inositol doesn?t seem to help psoriasis in people not taking lithium.

Interactions for Inositol

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Typical Dosage for Inositol

1.For panic disorder: 12 to 18 grams per day
2.For obsessive-compulsive disorder: inositol 18 grams per day
3.For treating symptoms associated with polycystic ovary syndrome: D-chiro-inositol 1200 mg per day
4.For treating lithium-related psoriasis: 6 grams daily

Schedule of Inositol

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Storage Requirements for Inositol

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Effects of Missed Dosage of Inositol

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Effects of Overdose of Inositol

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Lutein

About Lutein

Carotenoid, Xanthophyll, Dietary antioxidant.

Mechanism of Action of Lutein

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Pharmacokinets of Lutein

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Onset of Action for Lutein

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Duration of Action for Lutein

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Half Life of Lutein

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Side Effects of Lutein

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Contra-indications of Lutein

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Special Precautions while taking Lutein

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Lutein

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Interactions for Lutein

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Typical Dosage for Lutein

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Schedule of Lutein

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Storage Requirements for Lutein

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Effects of Missed Dosage of Lutein

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Effects of Overdose of Lutein

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Home Delivery for Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein and other medicines and health products. Home delivery services for alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein before they complete the sale. You can get this information while placing the order for alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein with the pharmacy.

Alpha-Lipoic Acid + Vitamin B Complex + Zinc + Chromium + Inositol + Lutein is a generic medicine name and there are several brands available for it. Some of the brands for alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein might be better known than alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein itself. If the pharmacy that's willing to deliver medicines to your home doesn't have alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein in stock, you can ask for one of the branded alternatives for alpha-lipoic acid + vitamin b complex + zinc + chromium + inositol + lutein.