Tricholine citrate + Sorbitol Pharmacology

Tricholine citrate

About Tricholine citrate
A quaternary ammonium compound, Used in liver disorders.
Mechanism of Action of Tricholine citrate
Tricholine citrate contains three molecules of choline. Due to choline`s lipotropic action, it is useful in the treatment of fatty infiltration and cirrhosis of liver. Choline converts fat into phospholipids like, lecithin, which is essential to biomembrane structure and its function. Lecithin is also a major component of high density lipoprotein (HDL), and is used to mobilize cholesterol from cell membrane. In patients with fatty liver, increased rate of phospholipid turnover has been observed following administration of choline.
Contra-indications of Tricholine citrate
1.Hypersensitivity to Tricholine citrate
Indications for Tricholine citrate
1.Liver disorders


About Sorbitol
A sugar alcohol, Sweetener, non-stimulant laxative, Osmotic diuretic, Genitourinary Irrigant.
Mechanism of Action of Sorbitol
Sorbitol is hydrolysed in the colon to short chain fatty acids. This fatty acid stimulates colonic propulsive motility by osmotically drawing water into the lumen.
Pharmacokinets of Sorbitol
Absorption: It is absorbed after oral administration
Side Effects of Sorbitol
1.Abdominal discomfort
Contra-indications of Sorbitol
Hypersensitivity to Sorbitol
Special Precautions while taking Sorbitol
1.Gastro intestinal obstruction
Typical Dosage for Sorbitol
Sorbitol 70% solution is available
Oral: 15 - 30 ml is taken at bed time, if needed dose can be increased to 60ml / day
Storage Requirements for Sorbitol
Store at room temperature. Protect from heat, light and moisture.Keep out of the reach of children
Effects of Missed Dosage Sorbitol
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule. Do not double the dose.
Effects of Overdose Sorbitol
Give supportive measures and symptomatic treatment.

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Tricholine citrate + Sorbitol is a generic medicine name and there are several brands available for it. Some of the brands for tricholine citrate + sorbitol might be better known than tricholine citrate + sorbitol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have tricholine citrate + sorbitol in stock, you can ask for one of the branded alternatives for tricholine citrate + sorbitol.

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