Antiemetic and Antivertigo actions: The central antimuscarinic actions of antihistamines are responsible for their antivertigo and antiemetic effects. They suppress end organ receptors or inhibit central cholinergic action. It also acts on Chemoreceptor trigger zone.
Migraine: Promethazine is used in migraine due to its sedative as well as antiemetic actions.
Anaesthetic adjuncts: Promethazine is used as anaesthetic adjunct due to its sedative, antiemetic and anticholinergic properties.
2. Extrapyramidal reactions
7. Dry mouth
9 .Blurred vision
13. Weight gain
14. Cholestatic jaundice
4.Patient taking antidepressants
2. Hepatic impairment
3. Cardiovascular disease
7. Cholestatic jaundice
8. Patient exposed to extreme heat or cold or phosphorus insecticides
9. Ceribrovascular disorder
10. Patient on ECT
11. Reaction to Insulin
12. Prostatic hyperplasia
14. Peptic ulcer
15. Slowly withdraw the drug with caution
CHILDREN (below 2 years): Contraindicated
7. Anticough ingredient
8. Anaesthetic adjuncts
Aluminium salts: Decrease efficacy.
Antacids should be given 1 hour before or 2 hours after promethazine.
Anticholinergics: Decrease efficacy and increase the anticholinergic side-effects of promethazine.
Barbiturates: Decrease efficacy.
Barbiturate anaesthetics: Increase frequency and severity of neuromuscular excitation and hypotension.
Bromocriptine: Efficacy decreased by promethazine.
Charcoal: Prevents absorption of promethazine.
Lithium: Disorientation, unconsciousness and extrapyramidal symptoms.
Meperidine: Excessive sedation and hypotension.
TCAs: Serum concentration increased by promethazine.
Propranolol: Increased plasma levels of both drugs.
MAOIs: Additive orthostatic hypotensive effect.
Lab tests: Pregnancy tests: False positive results.
Plasma bound iodine (PBI): Increase in PBI occurs.
Motion sickness: 50 mg / day in 2 divided dose
Allergy: 25 mg at bed time
Nausea: 12.5 - 25 mg / day
Sedation: 25 - 50 mg at bed time
Motion sickness: 12.5 - 25 mg / day
Allergy: 6.25 - 12. 5 mg 3 times a day
Sedation: 12.5 - 25 mg at bed time
Home Delivery for Promethazine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including promethazine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for promethazine and other medicines and health products. Home delivery services for promethazine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take promethazine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for promethazine before they complete the sale. You can get this information while placing the order for promethazine with the pharmacy.
Promethazine is a generic medicine name and there are several brands available for it. Some of the brands for promethazine might be better known than promethazine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have promethazine in stock, you can ask for one of the branded alternatives for promethazine.