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- Pharmacology For Dextromethorphan + Ammonium chloride + Cetirizine + Zinc
Dextromethorphan + Ammonium chloride + Cetirizine + Zinc Pharmacology
Dextromethorphan + Ammonium chloride + Cetirizine + Zinc
About Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/AMechanism of Action of Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/APharmacokinets of Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/AOnset of Action for Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/ADuration of Action for Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/AHalf Life of Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/ASide Effects of Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/AContra-indications of Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/ASpecial Precautions while taking Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/APregnancy Related InformationContraindicated; since Dextromethorphan and Cetirizine are contraindicated in pregnancy, the combination generic cannot be used in pregnancy.Old Age Related InformationN/ABreast Feeding Related InformationContraindicated; since Dextromethorphan and Cetirizine are contraindicated in lactation, the combination generic cannot be used in breast feeding mother.Children Related InformationN/AIndications for Dextromethorphan + Ammonium chloride + Cetirizine + Zinc1.Cough (Allergic and Unproductive cough)Interactions for Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/ATypical Dosage for Dextromethorphan + Ammonium chloride + Cetirizine + ZincAdult: 2 teaspoonful to be taken 3 - 4 times daily
Children: 1/ 2 - 1 teaspoonful to be taken 3 - 4 times daily
Schedule of Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/AStorage Requirements for Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/AEffects of Missed Dosage of Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/AEffects of Overdose of Dextromethorphan + Ammonium chloride + Cetirizine + ZincN/ADextromethorphan
About DextromethorphanA synthetic morphine (((dextrorotatory methyl ether of Levorphanol))) derivative,A synthetic narcotic antitussive.Mechanism of Action of DextromethorphanDextromethorphan hydrobromide is a selective antitussive which raises threshold of cough centre and suppresses the cough reflex by direct action on the cough centre in the medulla. It does not depress mucociliary function of the airway mucosa and is also devoid of constipating and addicting actions. (((Its antitussive action is not exerted through opioid receptors)))Pharmacokinets of DextromethorphanAbsorption: Well absorbed orally, Metabolism: Extensively metabolized by liver, Excretion: Excreted primarily through urine as metabolites; about 7 to 10% is excreted through faeces.Onset of Action for DextromethorphanBelow ? an hourDuration of Action for Dextromethorphan3 to 6 hoursHalf Life of Dextromethorphan11 hoursSide Effects of Dextromethorphan1. Dizziness
2. Nausea
3. Vomiting
4. Stomach pain
5. Drowsiness
6. Ataxia.Contra-indications of DextromethorphanPatients currently taking MAO inhibitors or within two weeks of discontinuing MAO inhibitors.Special Precautions while taking Dextromethorphan1. Atopic children
2. Sedated or deliberate patients
3. Those patients confined to the supine position
4. Patients sensitive to aspirin
Pregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationMay be used
Children below 2 years: Syrup, tablets, or lozenges are contraindicated
Indications for DextromethorphanChronic nonproductive cough.Interactions for DextromethorphanN/ATypical Dosage for DextromethorphanOral:
Chronic nonproductive cough:
Adults and children above 12 years: 10 to 20mg every 4 hours; or 30mg three to four times daily.
Maximum dose: 120mg daily.
Children (((age 6 to 12))): 5 to 10mg every four hours
Maximum dose: 60mg daily
Children (((age 2 to 6))): 2.5 to 5mg every four hours.
Maximum dose: 30mg daily.
Schedule of DextromethorphanN/AStorage Requirements for DextromethorphanStore at room temperature in a well closed light resistant container. Protect from excess heat and moisture. Keep out of reach of children.Effects of Missed Dosage of DextromethorphanTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of DextromethorphanRemove drug from the body by administration of activated charcoal and provide symptomatic treatment and supportive measures.Ammonium chloride
About Ammonium chlorideAmmonium compound, Acidifier,Expectorant.Mechanism of Action of Ammonium chlorideN/APharmacokinets of Ammonium chlorideN/AOnset of Action for Ammonium chlorideN/ADuration of Action for Ammonium chlorideN/AHalf Life of Ammonium chlorideN/ASide Effects of Ammonium chlorideN/AContra-indications of Ammonium chlorideN/ASpecial Precautions while taking Ammonium chlorideN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Ammonium chlorideN/AInteractions for Ammonium chlorideN/ATypical Dosage for Ammonium chlorideN/ASchedule of Ammonium chlorideN/AStorage Requirements for Ammonium chlorideN/AEffects of Missed Dosage of Ammonium chlorideN/AEffects of Overdose of Ammonium chlorideN/ACetirizine
About CetirizineSecond Generation H1 Antagonist, Metabolite of hydroxyzine, Antihistamine.Mechanism of Action of CetirizineThis drug is a selective peripheral H1 receptor antagonist. Thus it inhibits the allergic symptoms produced by histamines like cold, rhinorrhea, sneezing, urticaria etc. The drug has some mast cell stabilizing properties. It also inhibit eotaxin-induced eosinophil TEM through both dermal and lung micro vascular endothelial cells. So inhibit eosinophil chemotaxis and also inflammation caused by it.Pharmacokinets of CetirizineAbsorption- Well absorbed after oral administration
Distribution-Widely distributed in the body. 93% bound to the plasma proteins. It enters to the CNS in small amounts.
Metabolism-Metabolized in the liver to its metabolites by oxidative O-dealkylation
Excretion- Excreted through urine (50% as unchanged form) and a small amount through feces
Onset of Action for Cetirizine10-30 minDuration of Action for Cetirizine12-24hrsHalf Life of CetirizineIts plasma half life is 8.3 hrsSide Effects of Cetirizine1. Somnolence.
2. Fatigue
3. Malaise
4. Headache
5. Dry mouth
6. CNS stimulation in children
7. Dizziness
8. Tinnitus
9. Incordination
10. Blurred vision
12. Diplopia
13. Euphoria
14. Nervousness
15. Drowsiness
16. Excessive tiredness
17. Vomiting
18. Diarrhea
19. Sore throat
20. Stomach pain
Contra-indications of CetirizineHypersensitivity to the drug or hydroxyzine.Special Precautions while taking Cetirizine1. Renal impairment.
2. Hepatic dysfunction.
3. Haemodialysis.
4. Any work which require mental alertness like driving or machine operation.
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Cetirizine1. Sneezing
2. Rhinorrhoea
3. Postnasal discharge.
4. Common coughs
5. Colds.
6. Chronic urticaria
7. Dermatitis
8. Pruritic skin disorders
9. Hay fever
10. Angioedema
Interactions for CetirizineAlcohol: Avoid excessive alcohol consumption.Typical Dosage for CetirizineOral-
Adult - 10 mg daily, single dose
Children (6-12 years) -5 mg daily.
Schedule of CetirizineN/AStorage Requirements for CetirizineStore in cool, dry, dark placeEffects of Missed Dosage of CetirizineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CetirizineGive symptomatic and supportive treatment.Zinc
About ZincTrance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.Mechanism of Action of ZincZinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.Pharmacokinets of ZincAbsorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.Onset of Action for ZincN/ADuration of Action for ZincN/AHalf Life of ZincN/ASide Effects of Zinc1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes
Contra-indications of ZincN/ASpecial Precautions while taking Zinc1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction
Pregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Zinc1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia
Interactions for ZincFluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.
Typical Dosage for ZincAdults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of ZincN/AStorage Requirements for ZincStore at a temperature below 30 degree CEffects of Missed Dosage of ZincTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ZincProvide symptomatic treatment and supportive measuresHome Delivery for Dextromethorphan + Ammonium chloride + Cetirizine + Zinc in Your City
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Dextromethorphan + Ammonium chloride + Cetirizine + Zinc is a generic medicine name and there are several brands available for it. Some of the brands for dextromethorphan + ammonium chloride + cetirizine + zinc might be better known than dextromethorphan + ammonium chloride + cetirizine + zinc itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dextromethorphan + ammonium chloride + cetirizine + zinc in stock, you can ask for one of the branded alternatives for dextromethorphan + ammonium chloride + cetirizine + zinc.
