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- Pharmacology For Dextromethorphan + Cetylpyridinium chloride
Dextromethorphan + Cetylpyridinium chloride Pharmacology
Dextromethorphan + Cetylpyridinium chlorideAbout Dextromethorphan + Cetylpyridinium chlorideN/AMechanism of Action of Dextromethorphan + Cetylpyridinium chlorideN/APharmacokinets of Dextromethorphan + Cetylpyridinium chlorideN/AOnset of Action for Dextromethorphan + Cetylpyridinium chlorideN/ADuration of Action for Dextromethorphan + Cetylpyridinium chlorideN/AHalf Life of Dextromethorphan + Cetylpyridinium chlorideN/ASide Effects of Dextromethorphan + Cetylpyridinium chlorideN/AContra-indications of Dextromethorphan + Cetylpyridinium chlorideN/ASpecial Precautions while taking Dextromethorphan + Cetylpyridinium chlorideN/APregnancy Related InformationContraindicated; since Dextromethorphan and Cetylpyridinium chloride are contraindicated in pregnancy, the combination generic cannot be used in pregnancy.Old Age Related InformationN/ABreast Feeding Related InformationContraindicated; since Dextromethorphan and Cetylpyridinium chloride are contraindicated in lactation, the combination generic cannot be used in breast feeding motherChildren Related InformationN/AIndications for Dextromethorphan + Cetylpyridinium chloride1.Cough
Interactions for Dextromethorphan + Cetylpyridinium chlorideN/ATypical Dosage for Dextromethorphan + Cetylpyridinium chlorideAdult: 1 - 2 lozenges to be taken 4 - 6 times daily
Children above 6 years: 1 lozenges to be taken 4 - 6 times daily
Schedule of Dextromethorphan + Cetylpyridinium chlorideN/AStorage Requirements for Dextromethorphan + Cetylpyridinium chlorideN/AEffects of Missed Dosage of Dextromethorphan + Cetylpyridinium chlorideN/AEffects of Overdose of Dextromethorphan + Cetylpyridinium chlorideN/A
DextromethorphanAbout DextromethorphanA synthetic morphine (((dextrorotatory methyl ether of Levorphanol))) derivative,A synthetic narcotic antitussive.Mechanism of Action of DextromethorphanDextromethorphan hydrobromide is a selective antitussive which raises threshold of cough centre and suppresses the cough reflex by direct action on the cough centre in the medulla. It does not depress mucociliary function of the airway mucosa and is also devoid of constipating and addicting actions. (((Its antitussive action is not exerted through opioid receptors)))Pharmacokinets of DextromethorphanAbsorption: Well absorbed orally, Metabolism: Extensively metabolized by liver, Excretion: Excreted primarily through urine as metabolites; about 7 to 10% is excreted through faeces.Onset of Action for DextromethorphanBelow ? an hourDuration of Action for Dextromethorphan3 to 6 hoursHalf Life of Dextromethorphan11 hoursSide Effects of Dextromethorphan1. Dizziness
4. Stomach pain
6. Ataxia.Contra-indications of DextromethorphanPatients currently taking MAO inhibitors or within two weeks of discontinuing MAO inhibitors.Special Precautions while taking Dextromethorphan1. Atopic children
2. Sedated or deliberate patients
3. Those patients confined to the supine position
4. Patients sensitive to aspirin
Pregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationMay be used
Children below 2 years: Syrup, tablets, or lozenges are contraindicated
Indications for DextromethorphanChronic nonproductive cough.Interactions for DextromethorphanN/ATypical Dosage for DextromethorphanOral:
Chronic nonproductive cough:
Adults and children above 12 years: 10 to 20mg every 4 hours; or 30mg three to four times daily.
Maximum dose: 120mg daily.
Children (((age 6 to 12))): 5 to 10mg every four hours
Maximum dose: 60mg daily
Children (((age 2 to 6))): 2.5 to 5mg every four hours.
Maximum dose: 30mg daily.
Schedule of DextromethorphanN/AStorage Requirements for DextromethorphanStore at room temperature in a well closed light resistant container. Protect from excess heat and moisture. Keep out of reach of children.Effects of Missed Dosage of DextromethorphanTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of DextromethorphanRemove drug from the body by administration of activated charcoal and provide symptomatic treatment and supportive measures.
Cetylpyridinium chlorideAbout Cetylpyridinium chlorideA cationic quaternary ammonium compound with strong bactericidal and resistance to fungi, Antiseptic agent, antiplaque and antigingivitis.Mechanism of Action of Cetylpyridinium chlorideCetylpyridinium chloride is an antiseptic which exhibits antimicrobial properties against a number of oral bacteria and fungi. It possesses antiplaque and antigingivitis properties.Pharmacokinets of Cetylpyridinium chlorideAbsorption: Administered orally,Onset of Action for Cetylpyridinium chlorideN/ADuration of Action for Cetylpyridinium chlorideN/AHalf Life of Cetylpyridinium chlorideN/ASide Effects of Cetylpyridinium chloride1.Allergic reactions.Contra-indications of Cetylpyridinium chloride1.Hypersensitivity to the drugSpecial Precautions while taking Cetylpyridinium chloride1.Severe sore throat accompanied by high fever, headache, nausea, or vomiting
2.Sore throat or mouth irritations persisting more than 2 days
3.Do not use with persistent cough or fever, unless being treated by a medical provider for that illness
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Cetylpyridinium chloride1.As antiseptic in Mouth washes
Interactions for Cetylpyridinium chlorideN/ATypical Dosage for Cetylpyridinium chlorideMouth washes: 0.5 to 0.1%w/w; as required by the patient.
Adults and children over 6 years:
Lozenge: Dissolve one lozenge in mouth every 2 hours as required.
Schedule of Cetylpyridinium chlorideN/AStorage Requirements for Cetylpyridinium chlorideStore at a temperature below 250C. Protect from moisture and light. Keep out of reach of children.Effects of Missed Dosage of Cetylpyridinium chlorideTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Cetylpyridinium chlorideProvide symptomatic treatment and supportive measures
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