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- Generic Medicines
- Pharmacology For Tiotropium
TiotropiumAbout TiotropiumAnticholinergic(Muscarinic Antagonist) bronchodilator, Thiophene, Antiasthma,in COPD.Mechanism of Action of TiotropiumTiotropium selectively acts on bronchial muscle by binding very tightly to bronchial M1/M3 muscarinic receptors and produces long lasting bronchodilatation. It inhibits vagally mediated reflexes by antagonizing the actions of acetylcholine. It prevents the acetylcholine mediated increase in intracellular cyclic GMP concentration that results from interaction of acetylcholine with muscarinic receptor on bronchial smooth muscle. It does not depress the muco-ciliary clearance by bronchial epithelium. It blocks the cholinergic constrictor tone and acts primarily in the larger airways.Pharmacokinets of TiotropiumAbsorption: Not readily absorbed in to systemic circulationOnset of Action for TiotropiumN/ADuration of Action for TiotropiumN/AHalf Life of TiotropiumN/ASide Effects of Tiotropium1. Upper respiratory tract infections
6. Increased sputum
8. Dry mouth
11. Gastrointestinal distress
14. Back pain
17. Chest pain
19. Flu like symptoms
20. Loss of voice
21. Nasal congestion
22. Runny nose
24. Sore throat
25. Unpleasant taste
Contra-indications of Tiotropium1. Hypersensitivity to the drug
2. Hypersensitivity to Atropine or it`s derivatives
3. The recommended dose should not be exceeded
5. Tiotropium bromide rotacaps must not be swallowed
Special Precautions while taking Tiotropium1. Angle closure glaucoma
2. Prostatic hyperplasia
3. Bladder neck obstruction
4. Renal impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationContraindicatedIndications for Tiotropium1. Chronic obstructive pulmonary diseases
3. Chronic bronchitis
Interactions for TiotropiumN/ATypical Dosage for TiotropiumInhalation: Contents of one rotacap (18mcg) once daily; inhaled with the Rotahaler deviceSchedule of TiotropiumN/AStorage Requirements for TiotropiumStore in a cool dry place in a well closed container. Protect from Direct heat, light, and moisture. Avoid freezing. Keep out of reach of children. Shake well before use.
Effects of Missed Dosage of TiotropiumTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of TiotropiumIt is not readily absorbed in to systemic circulation. So acute overdose is unlikely to occur. Provide symptomatic treatment and supportive measures.
Home Delivery for Tiotropium in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including tiotropium.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for tiotropium and other medicines and health products. Home delivery services for tiotropium may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take tiotropium only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for tiotropium before they complete the sale. You can get this information while placing the order for tiotropium with the pharmacy.
Tiotropium is a generic medicine name and there are several brands available for it. Some of the brands for tiotropium might be better known than tiotropium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have tiotropium in stock, you can ask for one of the branded alternatives for tiotropium.