- Medicine India
- Generic Medicines
- Pharmacology For Fexofenadine
FexofenadineAbout FexofenadineSecond Generation H1 Antagonist, Antihistamine.Mechanism of Action of FexofenadineFexofenadine blocks one type of peripheral receptor for histamine (the H1 receptor) and thus prevents activation of H1 receptor-containing cells by histamine (Histamine is released from histamine-storing cells (mast cells) and then attaches to other cells that have receptors for histamine. The attachment of the histamine to the receptors causes the cell to be "activated," releasing other chemicals that produce the effects that we associate with allergy, e.g., sneezing.) and the allergic symptoms produced by it.Pharmacokinets of FexofenadineAbsorption- Rapidly absorbed after oral administration
Distribution- Widely distributed in the body. 60-70% bound to the plasma proteins
Metabolism- Metabolized in the liver to its metabolites
Excretion- Excreted through urine (10% as unchanged), bile and feces
Onset of Action for FexofenadineN/ADuration of Action for Fexofenadine14 hrsHalf Life of Fexofenadine14.4 hrsSide Effects of Fexofenadine1. Headache
4. Back pain
6. NauseaContra-indications of FexofenadineContraindicated in patients with hypersensitivity to the drug or other ingredientsSpecial Precautions while taking Fexofenadine1. Renal dysfunction
2. Any work which require mental alertness like driving and machine operationsPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Fexofenadine1. Hay fever
2. Runny nose
4. Tearing eyes
5. HivesInteractions for FexofenadineAn increase in the level of fexofenadine in plasma of 2-times was observed after co-administration of erythromycin or ketoconazole.Typical Dosage for FexofenadineOral-
Adult and children (12yrs)-
Allergic rhinitis:120mg once daily
Allergic skin conditions:180mg once daily
Schedule of FexofenadineN/AStorage Requirements for FexofenadineStore at room temperature and away from excess heat and moistureEffects of Missed Dosage of FexofenadineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Fexofenadine Give symptomatic and supportive treatment
Home Delivery for Fexofenadine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including fexofenadine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for fexofenadine and other medicines and health products. Home delivery services for fexofenadine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take fexofenadine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for fexofenadine before they complete the sale. You can get this information while placing the order for fexofenadine with the pharmacy.
Fexofenadine is a generic medicine name and there are several brands available for it. Some of the brands for fexofenadine might be better known than fexofenadine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have fexofenadine in stock, you can ask for one of the branded alternatives for fexofenadine.