Azatadine Pharmacology


About Azatadine
H1antagonist, anti-serotonin, anticholinergic (drying), Antihistamine.
Mechanism of Action of Azatadine
Azatadine acts by blocking the binding of histamine to receptors in the body. It does not prevent the actual release of histamine from mast cells. By blocking the binding of histamine, the release of other chemicals and increased blood supply to the area is prevented or decreased. This results in prevention or relief of the typical symptoms of an allergic reaction
Pharmacokinets of Azatadine
Absorption- Well absorbed after oral administration
Distribution- Widely distributed in the body
Metabolism- Metabolized in the liver to its metabolites
Excretion- Excreted via urine
Onset of Action for Azatadine
1-2 hrs
Duration of Action for Azatadine
12 hrs
Half Life of Azatadine
12 hrs
Side Effects of Azatadine
1. Difficulty breathing
2. Sleepiness
3. Fatigue
4. Dizziness
5. Headache
6. Dry mouth
7. Difficulty urinating
8. Enlarged prostate
9. Nervousness
10. Arthralgia
11. Pharyngitis
12. Increased appetite
13. Nausea
14. Weight gain
15. Diarrhea.
Contra-indications of Azatadine
1. Hypersensitivity to the drug
2. Glaucoma or increased pressure in the eye
3. Stomach ulcer
4. Enlarged prostate
5. Bladder problems
6. Difficulty urinating
7. Hyperthyroidism
8. Heart diseases
9. Asthma
10. MAO inhibitors therapy
Special Precautions while taking Azatadine
1. Any work which require mental alertness such as driving, operating machinery, or performing other hazardous activities
2. Alcohol dependence
3. Liver disease
4. Kidney disease
5. Peptic ulcer
6. Epilepsy
7. Pyloroduodenal ulcer
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Children Related Information
Use with caution
NEONATES- Contraindicated
Indications for Azatadine
1. Rhinitis.
2. Pruritis.
3. Urticaria.
4. Insect bites or stings.
Interactions for Azatadine
MAOIs & TCAs: Enhance anticholinergic side effects of azatadine.
Alcohol & Other CNS depressants: CNS depression potentiated.
Betahistine: Antagonises effects of azatadine.
Antimuscarinics: Increased antimuscarinic side effects.
Typical Dosage for Azatadine
1 tab/day Or 2 tab twice a day (in severe cases)
6-12 yrs - ? to 1 tab twice a day
1-6 yrs- ? tsp twice a day
Schedule of Azatadine
Storage Requirements for Azatadine
Stored at room temperature away from moisture and heat.
Effects of Missed Dosage of Azatadine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Azatadine
Give symptomatic and supportive treatment

Home Delivery for Azatadine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including azatadine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for azatadine and other medicines and health products. Home delivery services for azatadine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take azatadine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for azatadine before they complete the sale. You can get this information while placing the order for azatadine with the pharmacy.

Azatadine is a generic medicine name and there are several brands available for it. Some of the brands for azatadine might be better known than azatadine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have azatadine in stock, you can ask for one of the branded alternatives for azatadine.