Pheniramine Maleate Pharmacology

Pheniramine Maleate

About Pheniramine Maleate
First generation HistamineH1 antagonist ,Alkylamine derivative, Anti histamine.
Mechanism of Action of Pheniramine Maleate
This alkyl amine derivative has peripheral H1 receptor antagonist action and compete with histamine for binding to the receptors present on bronchi, uterus etc. This inhibits the activation of receptors and corresponding allergic symptoms produced by it. Centrally the drug also has some antimuscarinic activity.
Pharmacokinets of Pheniramine Maleate
Onset of Action for Pheniramine Maleate
Duration of Action for Pheniramine Maleate
Half Life of Pheniramine Maleate
19 hrs
Side Effects of Pheniramine Maleate
1. Drowsiness
2. Nervousness
3. Irritability
4. Incoordination
5. Lack of concentration
6. Dizziness
7. Tinnitus
8. Nausea
9. Vomiting
10. Difficulty in passing urine
11. Asthma
12. Wheezing
13. Swelling of the face lips or tongue
14. Hives
15. Itching
16. Skin rash
17. Fainting
Contra-indications of Pheniramine Maleate
1. Hypersensitivity to the drug or its ingredients
2. Porphyria
Special Precautions while taking Pheniramine Maleate
1. Heart disease
2. High blood pressure
3. Narrow angle glaucoma
4. Enlarged prostate gland
5. Any work which require mental alertness
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Children Related Information
Use with caution
NEONATES: Contraindicated
Indications for Pheniramine Maleate
1. Eczema
2. Dermatitis
3. Urticaria
4. Skin oedema
5. Itching due to insect bites
6. Photo-dermatitis
7. Rhinitis
8. Serum sickness
9. Paresis during pregnancy
10. Toxaemia and retention of placenta
11. Motion sickness
Interactions for Pheniramine Maleate
Alcohol and other CNS depressants (Hypnotics, Sedative, Tranquilizers, Antianxiety agents, Narcotic analgesics): Additive effect leading to profound CNS depression.
MAOIs: Prolong anticholinergic (drying) effects.
Anticholinergics (some) & Tricyclic Antidepressants: May have enhanced effect.
Aminoglycosides: Ototoxicity of aminoglycosides masked.
Typical Dosage for Pheniramine Maleate
Adult:15-30 mg 2 - 3 times daily.

Schedule of Pheniramine Maleate
Storage Requirements for Pheniramine Maleate
Stored at controlled room temperature. Protect from light and excessive heat. Keep out of reach of children.
Effects of Missed Dosage of Pheniramine Maleate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Pheniramine Maleate
Give symptomatic and supportive treatment

Home Delivery for Pheniramine Maleate in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including pheniramine maleate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for pheniramine maleate and other medicines and health products. Home delivery services for pheniramine maleate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take pheniramine maleate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for pheniramine maleate before they complete the sale. You can get this information while placing the order for pheniramine maleate with the pharmacy.

Pheniramine Maleate is a generic medicine name and there are several brands available for it. Some of the brands for pheniramine maleate might be better known than pheniramine maleate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have pheniramine maleate in stock, you can ask for one of the branded alternatives for pheniramine maleate.