Distribution: It is uniformly distributed over the inflamed intestinal mucosa. Small amount of the drug is distributed in protein bound form in the systemic circulation. Sulfasalazine and its metabolites cross the placenta.
Metabolism: It is rapidly metabolised by azoreductase enzyme in the intestinal mucosal wall to 5 amino salicylic acid and Sulfapyridine.
Excretion: Absorbed Sulfasalazine is excreted mainly in the urine.
4. Abdominal pain
13. Hypersensitivity reaction
14. Bone marrow depression
15. Blood dyscrasias
16. Stevens-Johnson syndrome
2. Renal impairment
3. Blood dyscrasia
4. G6PD deficiency
2. Crohn`s disease
3. Rheumatoid arthritis
Digoxin : Possibly reduced efficacy of digoxin.
Ulcerative colitis, Crohn`s disease: 1 g 3 - 4 times daily usually after meals
Maintenance dose: 2 g / day in 4 divided doses should continue indefinitely.
Rheumatoid arthritis: Initial dose: 1 g / day for 3-5 days, then gradually increase the dose up to 3 g/ day
Children above 2 years: Ulcerative colitis, Crohn`s disease: 40 - 60 mg / kg body weight / day in 3 - 6 divided doses. Maintenance dose: 20 - 30 mg / kg body weight / day in 3 - 6 divided doses
Home Delivery for Sulphasalazine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including sulphasalazine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sulphasalazine and other medicines and health products. Home delivery services for sulphasalazine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take sulphasalazine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sulphasalazine before they complete the sale. You can get this information while placing the order for sulphasalazine with the pharmacy.
Sulphasalazine is a generic medicine name and there are several brands available for it. Some of the brands for sulphasalazine might be better known than sulphasalazine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sulphasalazine in stock, you can ask for one of the branded alternatives for sulphasalazine.