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- Pharmacology For Piroxicam Topical + Capsaicin + Menthol + Methyl salicylate
Piroxicam Topical + Capsaicin + Menthol + Methyl salicylate Pharmacology
Piroxicam Topical + Capsaicin + Menthol + Methyl salicylate
About Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/AMechanism of Action of Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/APharmacokinets of Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/AOnset of Action for Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/ADuration of Action for Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/AHalf Life of Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/ASide Effects of Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/AContra-indications of Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/ASpecial Precautions while taking Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/AInteractions for Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/ATypical Dosage for Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/ASchedule of Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/AStorage Requirements for Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/AEffects of Missed Dosage of Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/AEffects of Overdose of Piroxicam Topical + Capsaicin + Menthol + Methyl salicylateN/APiroxicam Topical
About Piroxicam TopicalNSAID,Oxicam derivative, Analgesic,antiinflammatory.Mechanism of Action of Piroxicam TopicalDrug inhibits the biosynthesis and release of prostaglandins by inhibiting cyclooxygenase enzyme in a reversible manner. In this way it reduces the PG concentration in the synovial fluid. It also reduce platelet aggregation (prolong bleeding time), production of IgM rheumatoid factor, chemotaxis of leukocytes and ratio of T-helper to T- suppressor lymphocytes.Pharmacokinets of Piroxicam TopicalAbsorption - Poorly absorbed to the skin.Onset of Action for Piroxicam TopicalN/ADuration of Action for Piroxicam TopicalN/AHalf Life of Piroxicam TopicalN/ASide Effects of Piroxicam Topical1. Local skin reaction e.g. redness, itching
2. Contact dermatitis
3. Photosensitivity
4. BronchospasmContra-indications of Piroxicam Topical1. Hypersensitivity to the drugSpecial Precautions while taking Piroxicam Topical1.For external use only.
2.Do not apply the gel to broken area of skin.
3. Avoid contact of this medicine with the eyes and the moist membranes lining the inside of certain parts of the body, e.g. mouth, nasal passages (mucous membranes). Rinse with cold water if accidental contact occurs.
4.You should not cover the area being treated with airtight dressings such as bandages or other dressings, infected or irritated skin, or to open wounds
5.Renal diseases
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with caution
Breast Feeding Related InformationContraindicatedChildren Related InformationContraindicatedIndications for Piroxicam Topical1. Osteoarthritis in superficial joints such as the knee
2. Inflammation of the tissue around a joint (Periarthritis)
3. Tennis elbow (epicondylitis)
4. Inflammation of a tendon (Tendinitis)
5. Inflammation of a tendon sheath (tenosynovitis)
6. Sprains
7. Strains
Interactions for Piroxicam TopicalN/ATypical Dosage for Piroxicam TopicalPiroxicam should be applied with gentle massage only.
1g gel applied to the affected site 3 to 4 times daily. Review therapy after 4 weeks.
Schedule of Piroxicam TopicalN/AStorage Requirements for Piroxicam TopicalStore in a cool dry place, away from direct heat and light. Keep all medicines out of the reach of children.Effects of Missed Dosage of Piroxicam TopicalIf you miss applying Piroxicam at your usual time, apply it as soon as you remember. However if it is almost time for your next application, skip the missed one and continue applying at the usual times. Do not use two doses at the same time to compensate.Effects of Overdose of Piroxicam TopicalGive symptomatic and supportive treatmentCapsaicin
About CapsaicinA lipophilic capsaicinoid(methyl vanillyl nonenamide),substance P release inducer, A topical analgesic ,antineuralgic and antipruritic, rubefacient.Mechanism of Action of CapsaicinCapsaicin is a rubefacient. It produces reddening of the skin by dilatation of the blood vessel and gives a soothing feeling of warmth. It is also called as counterirritant because they produce their action by counter irritation. Irritation of the sensory nerve endings alters pain in the underlying muscle or joints that are served by the same nerves.
Capsaicin depletes the neurochemical substance P which transmits pain and desensitizes person to pain. Capsaicin produces a temporary reduction in pain.Pharmacokinets of CapsaicinN/AOnset of Action for CapsaicinN/ADuration of Action for CapsaicinN/AHalf Life of CapsaicinN/ASide Effects of Capsaicin1.Warm
2.Stinging
3.Burning
4.Skin redness
Contra-indications of CapsaicinHypersensitivity to CapsaicinSpecial Precautions while taking Capsaicin1.Wear gloves when applying cream.
2.Do not apply after a hot bath or shower or use it with a heating pad.
3.Avoid contact with eyes, mucus membranes or broken skin
4.Broken or irritated skin
5.Prolonged use
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with caution
Below 2 years:ContraindicatedIndications for Capsaicin1.Back pain
2.Bursitis
3.Fibromyalgia
4.Joint pain
5.Muscle pain
6.Nerve Pain
7.Osteoarthritis
8.Pain due to diabetic neuropathy
9.Post-herpetic neuralgia
10.Post-surgical neuropathic pain
Interactions for CapsaicinN/ATypical Dosage for CapsaicinTopical
For neuralgia or itching of the skin:
Adults: Apply 0.025% cream 3 or 4 times a day and rub well and if sufficient response is not obtained apply 0.075% cream.
Children: Same as adult dose
Below 2 years: Contraindicated
Schedule of CapsaicinN/AStorage Requirements for CapsaicinStore the medicine in a closed container at room temperature. Keep away from heat, moisture and direct light. Keep out of the reach of children.Effects of Missed Dosage of CapsaicinApply the missed dose as soon as remember and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the doses.Effects of Overdose of CapsaicinGive supportive measures and symptomatic treatment.Menthol
About MentholTerpenes and terpenoid, Antipruritic, decongestant, topical analgesic.Mechanism of Action of MentholMenthol acts as a local anesthetic on the respiratory passageways and causing cough suppression. When Menthol is rubbed on the skin, it acts as a rubefacient and causes localized vasodilatation; which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and mild local anaesthetic effect relieves itching. It has good soothing effect and acts as a demulcent. It also acts as a carminative.Pharmacokinets of MentholN/AOnset of Action for MentholN/ADuration of Action for MentholN/AHalf Life of MentholN/ASide Effects of Menthol1.Irritation
2.Anxiety
3.Excitement
4.Delirium
5.Colic
6.Nausea
7.Vomiting
8.Diarrhoea
9.Convulsions
10.Apnoea
11.Asystole
12.Contact dermatitis
13.Allergic reactions
Contra-indications of Menthol1. Hypersensitivity to the drug
2.Should not applies to broken, injured, or burned skin
Special Precautions while taking Menthol1.Should not apply Menthol directly in to or near the nostrils of small children or asthma patients
2.Prolonged use
3.Seizures
4.Should not take steam inhalation orally
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with caution
Children Related InformationUse with caution
below 2 years: ContraindicatedIndications for Menthol1. Rubefacient.
2.Ingredient in cough preparations
3.Antipruritic
4. Ingredient in ointment or liniment to treat sprains; joint and muscle pain
5.Sore throat
6.Cold sores
7.Hay fever
8.As an inhalant to relieve nasal, bronchial, or upper respiratory congestion
9.Sinusitis
10.Bronchial cough
11.Pharyngeal inflammation
Interactions for MentholN/ATypical Dosage for MentholDosage individualized based on requirements of the patient.
Lozenges: Dissolve lozenge (5%-10% menthol) slowly in the mouth hourly as needed by the patients.
Topical: Rubbed on the throat and chest in a layer loosely covered with a warm dry cloth; up to thrice daily.
In vaporizer: Menthol (3.2%) in a hot steam vaporizer can be used by adding 1 tbsp of solution for each quart of cold water, or 1tsp of solution for each pint, up to thrice daily
Schedule of MentholN/AStorage Requirements for MentholStore at a cool dry place in a well closed container. Protect from light and heat. Keep out of reach of children.Effects of Missed Dosage of MentholTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of MentholProvide symptomatic treatment and supportive measures.Methyl salicylate
About Methyl salicylateSalicylates, Rubefacient, counterirritant.Mechanism of Action of Methyl salicylateMethyl salicylate is a rubefacient. It produces reddening of the skin by dilatation of the blood vessel and gives a soothing feeling of warmth. It is also called as counterirritant because they produce their action by counter irritation. Irritation of the sensory nerve endings alters pain in the underlying muscle or joints that are served by the same nerves.Pharmacokinets of Methyl salicylateN/AOnset of Action for Methyl salicylateN/ADuration of Action for Methyl salicylateN/AHalf Life of Methyl salicylateN/ASide Effects of Methyl salicylateN/AContra-indications of Methyl salicylateN/ASpecial Precautions while taking Methyl salicylateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Methyl salicylateN/AInteractions for Methyl salicylateN/ATypical Dosage for Methyl salicylateN/ASchedule of Methyl salicylateN/AStorage Requirements for Methyl salicylateN/AEffects of Missed Dosage of Methyl salicylateN/AEffects of Overdose of Methyl salicylateN/AHome Delivery for Piroxicam Topical + Capsaicin + Menthol + Methyl salicylate in Your City
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Piroxicam Topical + Capsaicin + Menthol + Methyl salicylate is a generic medicine name and there are several brands available for it. Some of the brands for piroxicam topical + capsaicin + menthol + methyl salicylate might be better known than piroxicam topical + capsaicin + menthol + methyl salicylate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have piroxicam topical + capsaicin + menthol + methyl salicylate in stock, you can ask for one of the branded alternatives for piroxicam topical + capsaicin + menthol + methyl salicylate.
