Rocuronium Pharmacology


About Rocuronium
A nondepolarizing Neuromuscular Blocker, Skeletal Muscle Relaxant.
Mechanism of Action of Rocuronium
Rocuronium is a Non depolarizing neuromuscular blocker. competes with acetylcholine for cholino- ceptive sites at the postjunctional membrane and thereby blocks competitively the transmitter action of acetylcholine resulting in muscle paralysis. It can also release histamine in the body.
General anaesthesia: It is often administered during the induction of anaesthesia to relax muscles of the jaw, neck and airway and thereby facilitate laryngoscopy and endotracheal intubation. Following induction, continued muscle relaxation is required for many procedures to aid surgical exposure and to provide additional insurance of immobility.
Pharmacokinets of Rocuronium
Absorption: It is completely absorbed after parenteral administration. Distribution: It is distributed mainly in free form. Excretion: 1/3rd of the drug is excreted mainly in urine.
Onset of Action for Rocuronium
Duration of Action for Rocuronium
20 - 70 minute
Half Life of Rocuronium
Side Effects of Rocuronium
Contra-indications of Rocuronium
Hypersensitivity to Rocuronium
Special Precautions while taking Rocuronium
1.Hepatic disease
2.Renal impairment
4.Bronchogenic carcinoma
5.Electrolyte disturbances
6.Neuromuscular diseases
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Children Related Information
Use with caution
Indications for Rocuronium
1.Adjunct to general anesthesia
2.Skeletal muscle relaxation
Interactions for Rocuronium
Typical Dosage for Rocuronium
IV bolus
Maintenance dose:0.1mg/kg /day

Schedule of Rocuronium
Storage Requirements for Rocuronium
Store between 2 and 8 ?C. Protect from freezing
Effects of Missed Dosage of Rocuronium
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Rocuronium
Give symptomatic and supportive treatment. Administer atropine and Neostigmine for the reversal of neuromuscular action of Rocuronium.

Home Delivery for Rocuronium in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including rocuronium.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for rocuronium and other medicines and health products. Home delivery services for rocuronium may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take rocuronium only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for rocuronium before they complete the sale. You can get this information while placing the order for rocuronium with the pharmacy.

Rocuronium is a generic medicine name and there are several brands available for it. Some of the brands for rocuronium might be better known than rocuronium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have rocuronium in stock, you can ask for one of the branded alternatives for rocuronium.