Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants Pharmacology

Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

About Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Mechanism of Action of Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Pharmacokinets of Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Onset of Action for Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Duration of Action for Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Half Life of Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Side Effects of Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Contra-indications of Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Special Precautions while taking Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Pregnancy Related Information

Use with caution; since Alfacalcidol is used with caution in pregnancy

Old Age Related Information

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Breast Feeding Related Information

Use with caution; since Alfacalcidol is used with caution in lactation

Children Related Information

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Indications for Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

1.Rickets and Osteomalacia
2.Hypoparathyroidism with bone disease
3.Renal osteodystrophy
4.Osteoporosis

Interactions for Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Typical Dosage for Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

1 capsule / day

Schedule of Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Storage Requirements for Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Effects of Missed Dosage of Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Effects of Overdose of Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants

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Alfacalcidol

About Alfacalcidol

Nutritional supplement,Vitamin D derivative, Antihypoparathyroid, Antihypocalcemic.

Mechanism of Action of Alfacalcidol

Alfacalcidol is a prodrug of Vitamin D and is rapidly hydroxylated in the liver in to calcitriol. Vitamin D exerts it`s action by influencing calcium homoeostasis. It increases the intestinal absorption of calcium and phosphate. It binds to the cytoplasmic Vitamin D receptor and translocates to the nucleus and thus increases the synthesis of specific m RNA and regulates protein synthesis. It increases the synthesis of a carrier protein for calcium called "calbindin" or calcium binding protein. Activation of Vitamin D receptor enhances endocytotic capture of calcium and it`s transport across duodenal mucosal cells in a vesicular form. Vitamin D promotes resorption of calcium and phosphate from bone by enhancing recruitment and differentiation of osteoclast precursors in the bone remodeling units. It helps in bone mineralization.

Pharmacokinets of Alfacalcidol

Absorption: Well absorbed orally, Distribution: Widely distributed in a protein bound form. It is stored in adipose tissue and liver. Metabolism: It is hydroxylated in to calcitriol in liver. Excretion: Excreted mainly through bile.

Onset of Action for Alfacalcidol

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Duration of Action for Alfacalcidol

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Half Life of Alfacalcidol

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Side Effects of Alfacalcidol

1.Hypercalcaemia
2.Fatigue
3.Weakness
4.Diarrhoea
5.Vomiting
6.Sluggishness
7.Albuminuria
8.Polyuria
9.Calcification of soft tissues (blood vessels, parenchymal organs including heart)
10.Renal stones
11.Growh retardation in children
12.Hypertension
13.Anorexia
14.Nausea
15.Constipation
16.Hyperphosphataemia.

Contra-indications of Alfacalcidol

1.Hypercalcaemia
2.Hypervitaminosis D
3.Hyperphosphataemia (except when occurring with hypoparathyroidism
4.Hypermagnesaemia.

Special Precautions while taking Alfacalcidol

1 Renal impairment
2.Hypercalciurea
3.Renal stones
4.Coronary diseases.

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Alfacalcidol

1.Rickets and Osteomalacia
2.Hypoparathyroidism with bone disease
3.Renal osteodystrophy
4.Osteoporosis

Interactions for Alfacalcidol

Digitallis preparations: Cardiac arrhythmias precipitated.
Thiazide Diuretics: Hypercalcaemic response enhanced.
Barbiturates & other enzyme inducing anticonvulsants: Reduce efficacy.
Minteral Oil: Prolonged use reduces efficacy.
Cholestyramine, Cholestipol, Sucralfate, Aluminium based Antacids: Reduced efficacy by decreasing absorption of alfacalcidol.
Magnesium based Antacids or Laxatives: Hypermagnesaemia in those on chronic renal dialysis.

Typical Dosage for Alfacalcidol

Oral:
Starts with 1mcg daily. Adjusted based on patients response to 2mcg daily if required.
Children over 20kg: Starts with 1mcg daily. Adjusted based on patient`s response.
Children under 20kg: 0.5mcg daily or 0.05mcg/kg/day

Schedule of Alfacalcidol

Storage Requirements for Alfacalcidol

Store in a well closed container in a cool place. Protect from light and excess heat. Keep out of reach of children.

Effects of Missed Dosage of Alfacalcidol

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Alfacalcidol

Provide supportive and symptomatic treatment. Stops the treatment and starting a low calcium diet. Increases the fluid intake and administer Loop diuretics like furosemide may be given with saline I.V. infusion to increase calcium excretion. Calcitonin may decrease hypercalcaemia.

Vitamin B-Complex

About Vitamin B-Complex

Vitamin B-complex are group of vitamins, which include Thiamine (B1),Riboflavin (B2),Niacin (B3),Pantothenic acid (B5),Pyridoxine (B6),Cyanocobalamin (B12),Folic acid and Biotin.
These vitamins are essential for the breakdown of carbohydrates into glucose (this provides energy for the body),the breakdown of fats and proteins (which aids the normal functioning of the nervous system),muscle tone in the stomach and intestinal tract,Skin,Hair,Eyes,Mouth and Liver

Mechanism of Action of Vitamin B-Complex

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Pharmacokinets of Vitamin B-Complex

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Onset of Action for Vitamin B-Complex

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Duration of Action for Vitamin B-Complex

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Half Life of Vitamin B-Complex

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Side Effects of Vitamin B-Complex

1.Drowsiness
2.Headache
3.Diarrhoea
4.Nausea.
5.Numbness of the skin

Contra-indications of Vitamin B-Complex

Hypersensitivity to the ingredient of Vitamin B-complex

Special Precautions while taking Vitamin B-Complex

1.Pernecious anaemia
2.Patient receiving dialysis

Pregnancy Related Information

May be used.

Old Age Related Information

May be used.

Breast Feeding Related Information

May be used.

Children Related Information

May be used.

Indications for Vitamin B-Complex

1.Vitamin deficiency states
2. As an adjuvant to antibiotic therapy
3. Combinations with lactobacillus are indicated in aphthous stomatitis, thrush.

Interactions for Vitamin B-Complex

Sulfinpyrazone: Uricosuric effect of sulfinpyrazone may be inhibited by niacin.
Levodopa: Pyridoxine reduces efficacy of levodopa. Avoid supplemental vitamins that contain greater then 5 mg pyridoxine in the daily dose.
Phenobarbital: Serum levels of Phenobarbital may be decreased if used concomitantly with pyridoxine.
Phenytoin: Pyridoxine decreases serum levels of phenytoin.
Dapsone: PABA antagonizes anti-malarial effect of dapsone.

Typical Dosage for Vitamin B-Complex

I tablet /day

Schedule of Vitamin B-Complex

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Storage Requirements for Vitamin B-Complex

Store at room temperature. Keep out of the reach of children.Protect from heat, light and moisture.

Effects of Missed Dosage of Vitamin B-Complex

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule. Do not double the dose.

Effects of Overdose of Vitamin B-Complex

Give supportive measures and symptomatic treatment.

Minerals

About Minerals

Dietary mineral supplement, Nutritional supplement.

Mechanism of Action of Minerals

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Pharmacokinets of Minerals

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Onset of Action for Minerals

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Duration of Action for Minerals

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Half Life of Minerals

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Side Effects of Minerals

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Contra-indications of Minerals

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Special Precautions while taking Minerals

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Minerals

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Interactions for Minerals

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Typical Dosage for Minerals

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Schedule of Minerals

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Storage Requirements for Minerals

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Effects of Missed Dosage of Minerals

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Effects of Overdose of Minerals

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About

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Mechanism of Action of

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Half Life of

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Side Effects of

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Contra-indications of

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Special Precautions while taking

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for

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Interactions for

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Typical Dosage for

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Schedule of

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Storage Requirements for

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Effects of Missed Dosage of

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Effects of Overdose of

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Home Delivery for Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants in Your City

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Alfacalcidol + Vitamin B-Complex + Minerals + Antioxidants is a generic medicine name and there are several brands available for it. Some of the brands for alfacalcidol + vitamin b-complex + minerals + antioxidants might be better known than alfacalcidol + vitamin b-complex + minerals + antioxidants itself. If the pharmacy that's willing to deliver medicines to your home doesn't have alfacalcidol + vitamin b-complex + minerals + antioxidants in stock, you can ask for one of the branded alternatives for alfacalcidol + vitamin b-complex + minerals + antioxidants.