Prednisone Pharmacology
Prednisone
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-a, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemo taxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction
2.Euphoria
3.Vertigo Headache
4.Seizure
5.Hypertension
6.Arrhythmia
7.Thromboembolism
8.Heart failure
9.Peptic ulcer
10.Increased appetite
11.Osteoporosis
2.Gastric ulcer
3.Hypertension
4.Osteoporosis
5.Diabetes mellitus
6.Hypothyroidism
7.Cirrhosis
8.Diverticulitis
9.Ulcerative colitis
10.Thromboembolic disorders
11.Seizures
12.Myasthenia gravis
13.Heart failure
14.Tuberculosis
15.Ocular herpes simplex
2.Multiple sclerosis
3.Tuberculosis
5 - 60mg / day in single or divided doses
Multiple sclerosis:200mg/day for 7 days and then 80mg very alternate day for 1 month.
Tuberculosis:40-60mg/day for 1 - 2 months
Home Delivery for Prednisone in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including prednisone.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for prednisone and other medicines and health products. Home delivery services for prednisone may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take prednisone only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for prednisone before they complete the sale. You can get this information while placing the order for prednisone with the pharmacy.
Prednisone is a generic medicine name and there are several brands available for it. Some of the brands for prednisone might be better known than prednisone itself. If the pharmacy that's willing to deliver medicines to your home doesn't have prednisone in stock, you can ask for one of the branded alternatives for prednisone.
