Dimethicone Pharmacology


About Dimethicone
Oral anti -foaming agent, a flexible silicone polymer, Antiflatulent ,Antibloating agent.
Mechanism of Action of Dimethicone
Activated Dimethicone relieves flatulence by dispensing and preventing formation of mucus surrounding gas pockets in the gastro-intestinal tract. It lowers the surface tension of the gas bubbles and bringing together all the small bubbles of gas (coalesce) to form a large bubble, which is then expelled. Thus the gas is freed by belching or passing flatus.
Antiflatulents are added to an antacid gum coating to be effective antigas materials and eliminate trapped gas. The most common antigas material is Dimethicone and when mixed with silicone dioxide becomes Simethicone. Simethicone is also referred to as activated Dimethicone. Simethicone is the most common antigas material and may be the only drug approved antiflatulent.
As the antacid chewing tablet is chewed, the active antacid and antiflatulent in the gum coating is released into the saliva and ingested to give relief from gastrointestinal disturbances in the gastro-intestinal tract.
Besides its antigas effect, Simethicone used in a gum coating can also improve the smoothness of the coating. Activated Dimethicone helps to relieve pain and bloating caused by trapped wind.
Pharmacokinets of Dimethicone
Onset of Action for Dimethicone
Duration of Action for Dimethicone
Half Life of Dimethicone
Side Effects of Dimethicone
Contra-indications of Dimethicone
Hypersensitivity to Dimethicone activated
Special Precautions while taking Dimethicone
Kidney failure
Pregnancy Related Information
Use with caution
Old Age Related Information
Breast Feeding Related Information
Use with caution
Children Related Information
Indications for Dimethicone
1. Flatulent dyspepsia
2. Postoperative distension
3. Gastric Distention
4. Functional digestive disorders
5. Stomach pain
6. Burning
7. Nausea and excess gas (dyspepsia)
Interactions for Dimethicone
Typical Dosage for Dimethicone
125 - 166 mg taken half an hour before food.
Dimethicone in a coated chewing gum: 5 mg - 200 mg per piece of coated gum.
With an antacid: 20 mg -50 mg of Dimethicone
Schedule of Dimethicone
Storage Requirements for Dimethicone
Stored at room temperature (15-30?C) away from moisture and heat.
Effects of Missed Dosage of Dimethicone
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Dimethicone
Give symptomatic and supportive treatment.

Home Delivery for Dimethicone in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including dimethicone.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dimethicone and other medicines and health products. Home delivery services for dimethicone may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take dimethicone only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dimethicone before they complete the sale. You can get this information while placing the order for dimethicone with the pharmacy.

Dimethicone is a generic medicine name and there are several brands available for it. Some of the brands for dimethicone might be better known than dimethicone itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dimethicone in stock, you can ask for one of the branded alternatives for dimethicone.