Magaldrate + Methyl Polysiloxane + Oxethazaine Pharmacology

Magaldrate + Methyl Polysiloxane + Oxethazaine

About Magaldrate + Methyl Polysiloxane + Oxethazaine
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Mechanism of Action of Magaldrate + Methyl Polysiloxane + Oxethazaine
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Pharmacokinets of Magaldrate + Methyl Polysiloxane + Oxethazaine
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Onset of Action for Magaldrate + Methyl Polysiloxane + Oxethazaine
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Duration of Action for Magaldrate + Methyl Polysiloxane + Oxethazaine
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Half Life of Magaldrate + Methyl Polysiloxane + Oxethazaine
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Side Effects of Magaldrate + Methyl Polysiloxane + Oxethazaine
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Contra-indications of Magaldrate + Methyl Polysiloxane + Oxethazaine
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Special Precautions while taking Magaldrate + Methyl Polysiloxane + Oxethazaine
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Magaldrate + Methyl Polysiloxane + Oxethazaine
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Interactions for Magaldrate + Methyl Polysiloxane + Oxethazaine
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Typical Dosage for Magaldrate + Methyl Polysiloxane + Oxethazaine
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Schedule of Magaldrate + Methyl Polysiloxane + Oxethazaine
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Storage Requirements for Magaldrate + Methyl Polysiloxane + Oxethazaine
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Effects of Missed Dosage of Magaldrate + Methyl Polysiloxane + Oxethazaine
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Effects of Overdose of Magaldrate + Methyl Polysiloxane + Oxethazaine
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Magaldrate

About Magaldrate
Chemical complex of aluminum and magnesium hydroxides, Antacid.
Mechanism of Action of Magaldrate
This neutralizes the gastric acid and increases the gastric pH. This reduces the direct acid irritant effect. It also enhances mucosal barrier integrity and improves gastroesophageal sphincter tone.
Pharmacokinets of Magaldrate
Absorption- Moderately absorbed after oral administration. Distribution- It is distributed through locally. Excretion- Excreted through feces and a small amount through breast milk.
Onset of Action for Magaldrate
20minutes
Duration of Action for Magaldrate
20 to 180 minutes
Half Life of Magaldrate
N/A
Side Effects of Magaldrate
1. Constipation
2. Diarrhea
3. Increased urine pH
4. Decreased serum potassium levels
5. Increased serum calcium levels
Contra-indications of Magaldrate
1. Hypersensitivity to the drug or any ingredients of it
2. Renal impairment or diseases
3. Hypophosphatemia
Special Precautions while taking Magaldrate
1.Take this medicine between meals and at bedtime.
2.Shake the oral liquid well before each use.
3.Chew the chewable tablet before swallowing.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Magaldrate
1. Peptic ulcer
2. Gastritis
3. Reflux oesophagitis
4. Gastric hyperacidity
Interactions for Magaldrate
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Typical Dosage for Magaldrate
Oral-
Adults-
Suspension: 5 to 10 ml between meals and at bedtime with water
Schedule of Magaldrate
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Storage Requirements for Magaldrate
Store at room temperature (15 - 25 degree C). Keep out of reach of children.
Effects of Missed Dosage of Magaldrate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Magaldrate
Give symptomatic and supportive treatment.

Methyl Polysiloxane

About Methyl Polysiloxane
Siloxanes, Antiflatulent.
Mechanism of Action of Methyl Polysiloxane
Methyl Polysiloxane relieves flatulence by dispensing and preventing formation of mucus surrounding gas pockets in the gastro-intestinal tract. It lowers the surface tension of the gas bubbles and bringing together all the small bubbles of gas (coalesce) to form a large bubble, which is then expelled. Thus the gas is freed by belching or passing flatus.
Antiflatulents are added to an antacid gum coating to be effective antigas materials and eliminate trapped gas.
Pharmacokinets of Methyl Polysiloxane
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Onset of Action for Methyl Polysiloxane
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Duration of Action for Methyl Polysiloxane
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Half Life of Methyl Polysiloxane
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Side Effects of Methyl Polysiloxane
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Contra-indications of Methyl Polysiloxane
Hypersensitivity to Methyl Polysiloxane
Special Precautions while taking Methyl Polysiloxane
Kidney failure
Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Methyl Polysiloxane
1. Flatulent dyspepsia
2. Postoperative distension
3. Gastric Distention
4. Functional digestive disorders
5. Stomach pain
6. Burning
7. Nausea and excess gas (dyspepsia)
Interactions for Methyl Polysiloxane
N/A
Typical Dosage for Methyl Polysiloxane
125 - 166 mg taken half an hour before food.
Methyl Polysiloxane in a coated chewing gum: 5 mg - 200 mg per piece of coated gum.
With an antacid: 20 mg -50 mg of Methyl Polysiloxane
Schedule of Methyl Polysiloxane
N/A
Storage Requirements for Methyl Polysiloxane
Stored at room temperature (15-30?C) away from moisture and heat.
Effects of Missed Dosage of Methyl Polysiloxane
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Methyl Polysiloxane
Give symptomatic and supportive treatment.

About
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Contra-indications of
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Special Precautions while taking
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for
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Interactions for
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Typical Dosage for
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Schedule of
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