Alginic Acid + Magaldrate + Simethicone Pharmacology

Alginic Acid + Magaldrate + Simethicone

About Alginic Acid + Magaldrate + Simethicone
N/A
Mechanism of Action of Alginic Acid + Magaldrate + Simethicone
N/A
Pharmacokinets of Alginic Acid + Magaldrate + Simethicone
N/A
Onset of Action for Alginic Acid + Magaldrate + Simethicone
N/A
Duration of Action for Alginic Acid + Magaldrate + Simethicone
N/A
Half Life of Alginic Acid + Magaldrate + Simethicone
N/A
Side Effects of Alginic Acid + Magaldrate + Simethicone
N/A
Contra-indications of Alginic Acid + Magaldrate + Simethicone
N/A
Special Precautions while taking Alginic Acid + Magaldrate + Simethicone
N/A
Pregnancy Related Information
Use with caution
Old Age Related Information
N/A
Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for Alginic Acid + Magaldrate + Simethicone
1.Acid Indigestion
2.Dyspepsia
3.Peptic ulcers
4.Gastro-esophageal reflux diseases
5.Heartburn
6.Gastritis
Interactions for Alginic Acid + Magaldrate + Simethicone
N/A
Typical Dosage for Alginic Acid + Magaldrate + Simethicone
Take 1 tablespoonful suspension after each meal and at bed time
Schedule of Alginic Acid + Magaldrate + Simethicone
N/A
Storage Requirements for Alginic Acid + Magaldrate + Simethicone
N/A
Effects of Missed Dosage of Alginic Acid + Magaldrate + Simethicone
N/A
Effects of Overdose of Alginic Acid + Magaldrate + Simethicone
N/A

Alginic Acid

About Alginic Acid
Naturally occurring hydrophilic colloidal polysaccharide, Protective agent against GERDs.
Mechanism of Action of Alginic Acid
This naturally occurring hydrophilic colloidal polysaccharide obtained from Sargassum Seaweeds reacts with saliva and produces a foamy froth that layers on the liquid in the stomach. Alginic acid powder swells when wetted with water. This may prevent reflux of acid into the esophagus by keeping the gastric contents in place and reduce the likelihood of reflux irritating the lining of the esophagus. The sodium calcium alginate fibres in haemostatic wound dressings absorbed by body fluids, as the calcium in the fiber is exchanged for sodium from the body fluids mixed salts of sodium and calcium alginate, and processed into non-woven fabric that is used in wound dressings. It binds with heavy metals and radioactive substances to its own molecules. It cannot be broken down by bile or saliva to be absorbed and secreted from the body together with heavy metals and radioactive substances.
Pharmacokinets of Alginic Acid
When ingested, almost all of the alginic acid remains undigested and is excreted either unchanged or as an alginate.
Onset of Action for Alginic Acid
N/A
Duration of Action for Alginic Acid
30 to 60 minutes
Half Life of Alginic Acid
N/A
Side Effects of Alginic Acid
1. Abdominal distension
2. Flatulence
3. Chalky taste in your mouth
4. Constipation
5. Diarrhea
6. Nausea
7. Vomiting.
Contra-indications of Alginic Acid
1. Hypersensitivity to the drug
2. Heart failure.
3. Renal failure.
Special Precautions while taking Alginic Acid
1.Allergies to medicines, foods, or other substances
2.Alzheimer disease
3.Appendicitis
4.Diarrhoea
5.Stomach blockage
6.Kidney problems
7.Liver problems
8.Ileostomy
9.Congestive heart failure
10.Decreased urination
11.Fluid retention
12.Rectal bleeding of unknown cause
13.Recently had stomach bleeding
14.Patient on low salt diet
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Alginic Acid
1. Heartburn (including heartburn of pregnancy)
2. Dyspepsia
3. Reflux oesophagitis
4. Hiatus hernia.
5. Protect inflamed areas near the entrance to the stomach (Sodium alginate)

Interactions for Alginic Acid
N/A
Typical Dosage for Alginic Acid
Take the drug as directed by the physician.
Schedule of Alginic Acid
N/A
Storage Requirements for Alginic Acid
Store below 25?C in a tightly closed container.
Effects of Missed Dosage of Alginic Acid
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Alginic Acid
Give symptomatic and supportive treatment.

Magaldrate

About Magaldrate
Chemical complex of aluminum and magnesium hydroxides, Antacid.
Mechanism of Action of Magaldrate
This neutralizes the gastric acid and increases the gastric pH. This reduces the direct acid irritant effect. It also enhances mucosal barrier integrity and improves gastroesophageal sphincter tone.
Pharmacokinets of Magaldrate
Absorption- Moderately absorbed after oral administration. Distribution- It is distributed through locally. Excretion- Excreted through feces and a small amount through breast milk.
Onset of Action for Magaldrate
20minutes
Duration of Action for Magaldrate
20 to 180 minutes
Half Life of Magaldrate
N/A
Side Effects of Magaldrate
1. Constipation
2. Diarrhea
3. Increased urine pH
4. Decreased serum potassium levels
5. Increased serum calcium levels
Contra-indications of Magaldrate
1. Hypersensitivity to the drug or any ingredients of it
2. Renal impairment or diseases
3. Hypophosphatemia
Special Precautions while taking Magaldrate
1.Take this medicine between meals and at bedtime.
2.Shake the oral liquid well before each use.
3.Chew the chewable tablet before swallowing.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Magaldrate
1. Peptic ulcer
2. Gastritis
3. Reflux oesophagitis
4. Gastric hyperacidity
Interactions for Magaldrate
N/A
Typical Dosage for Magaldrate
Oral-
Adults-
Suspension: 5 to 10 ml between meals and at bedtime with water
Schedule of Magaldrate
N/A
Storage Requirements for Magaldrate
Store at room temperature (15 - 25 degree C). Keep out of reach of children.
Effects of Missed Dosage of Magaldrate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Magaldrate
Give symptomatic and supportive treatment.

Simethicone

About Simethicone
Oral anti-foaming agent, Silicones, Antiflatulent.
Mechanism of Action of Simethicone
This anti-gas (anti-flatulence) medication acts in the stomach and intestines to change the surface tension of gas bubbles, enabling smaller bubbles to join together into bigger bubbles. It results elimination of gas more easily by belching or passing flatus.
Pharmacokinets of Simethicone
Excretion- Excreted through feces.
Onset of Action for Simethicone
N/A
Duration of Action for Simethicone
N/A
Half Life of Simethicone
N/A
Side Effects of Simethicone
1. Bloating
2. Constipation
3. Diarrhea
4. Gas
5. Heartburn
Contra-indications of Simethicone
1. Hypersensitivity to the drug
2. Liver disease
3. Kidney disease
4. Serious illness
Special Precautions while taking Simethicone
1.Swallow the tablets and capsules with a full glass of water.
2.Chew the chewable tablets thoroughly before swallowing.
3.Shake the drops well before using them.
4.To make administration easier, the drops can be mixed with 30 ml (2 tablespoons) of water or another liquid.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Simethicone
1. Abdominal pain which is due to excessive gas in the digestive tract
2. Before gastroscopy or radiography of the bowel
Interactions for Simethicone
N/A
Typical Dosage for Simethicone
Oral-
Adults and teenagers-
60 -125mg four times a day, after meals and at bedtime. Not more than 500 mg should be taken in twenty-four hours.
Chewable tablets:
Adults and teenagers-
40 -125 mg four times a day, after meals and at bedtime or 150 mg three times a day, after meals. Not more than 500 mg should be taken in twenty-four hours.
Suspension:
Adults and teenagers-
40 -95 mg four times a day, after meals and at bedtime. Not more than 500 mg should be taken in twenty-four hours.
Schedule of Simethicone
N/A
Storage Requirements for Simethicone
Stored at room temperature (15-30?C) away from moisture and heat.
Effects of Missed Dosage of Simethicone
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Simethicone
Give symptomatic and supportive treatment.

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