Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid Pharmacology

Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid

About Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Mechanism of Action of Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Pharmacokinets of Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Onset of Action for Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Duration of Action for Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Half Life of Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Side Effects of Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Contra-indications of Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Special Precautions while taking Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Pregnancy Related Information
Use with caution
Old Age Related Information
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Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
Alginic acid is used for reflux oesophagitis.
1.Hiatus hernia with hyperacidity
2.Reflux oesophagitis
Interactions for Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
N/A
Typical Dosage for Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
1 -2 tablets to be taken 3 times daily usually after meals
Schedule of Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Storage Requirements for Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Effects of Missed Dosage of Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Effects of Overdose of Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid
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Aluminium Hydroxide

About Aluminium Hydroxide
Antacid,Antidote,Protectant( Topical), In hyperacidity; hyperphosphatemia.
Mechanism of Action of Aluminium Hydroxide
It neutralizes and reduces stomach acid relieving heartburn (acid reflux, GERD) and indigestion. This results increased pH and reduce the pepsin activity. It also binds to the phosphate in the gut and form a nonsoluble nonabsorbable aluminium phosphate complex.
Pharmacokinets of Aluminium Hydroxide
Absorption- Poorly absorbed.Excretion- Excreted through feces and breast milk
Onset of Action for Aluminium Hydroxide
N/A
Duration of Action for Aluminium Hydroxide
20 to 180minutes
Half Life of Aluminium Hydroxide
N/A
Side Effects of Aluminium Hydroxide
1. Loss of appetite
2. Constipation
3. Hypophosphatemia
4. Osteomalacia
5. Confusion
6. Unusual tiredness or discomfort
7. Muscle weakness
8. Encephalopathy
Contra-indications of Aluminium Hydroxide
1. Hypersensitivity to the drug
2. Renal failure
3. Hypertension
4. Heart disease
5. Kidney disease
6. Gastrointestinal bleeding.
Special Precautions while taking Aluminium Hydroxide
1. Stomach problems
2. Allergies
Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
May be used
Indications for Aluminium Hydroxide
1. Gastric hyperacidity
2. Ulcers
3. Digestive disorders
4. Hyperphosphatemia
5. Oesophagitis
6. Hiatal hernia
7. Gastritis
Interactions for Aluminium Hydroxide
N/A
Typical Dosage for Aluminium Hydroxide
Oral-
Acidity and Hyperphosphatemia -
Adult-
500-1500mg tablet or capsule 1 hr after meals and at bed time
5 to 30 ml suspension1 hr after meals and at bed time as needed
Schedule of Aluminium Hydroxide
N/A
Storage Requirements for Aluminium Hydroxide
Store it at room temperature and away from excess heat and moisture. Refrigerate the suspension. Do not freeze.
Effects of Missed Dosage of Aluminium Hydroxide
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Aluminium Hydroxide
Give symptomatic and supportive treatment

Magnesium Hydroxide

About Magnesium Hydroxide
Mineral, Magnesium compound, Antacid and laxative.
Mechanism of Action of Magnesium Hydroxide
It neutralize the gastric acid (where the hydroxide ions from the Mg(OH)2 combine with acidic H+ ions produced in the form of hydrochloric acid by parietal cells in the stomach). This relieves the hyperacidity problems in the stomach.
Pharmacokinets of Magnesium Hydroxide
N/A
Onset of Action for Magnesium Hydroxide
N/A
Duration of Action for Magnesium Hydroxide
N/A
Half Life of Magnesium Hydroxide
N/A
Side Effects of Magnesium Hydroxide
1. Stomach cramps
2. Upset stomach
3. Vomiting
4. Diarrhea
5. Black/tarry stools
6. Rectal bleeding.
7. Constipation
8. Loss of appetite
9. Unusual tiredness
10. Muscle weakness
11. Hypermagnesaemia
12. Renal failure
Contra-indications of Magnesium Hydroxide
1. Hypersensitivity to the drug
2. Kidney disease
3. Stomach/abdominal pain
4. Nausea
5. Vomiting
Special Precautions while taking Magnesium Hydroxide
1. Colostomy
2. Dehydration
3. Diarrhea
4. Intestinal problems like colitis
5.Do not take any other medication within 1 to 2 hours of taking this medication.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Less than 6 Years : Contraindicated
Indications for Magnesium Hydroxide
1. Constipation
2. Peptic ulcer
3. Hiatal hernia
Interactions for Magnesium Hydroxide
N/A
Typical Dosage for Magnesium Hydroxide
Oral-
Adult-
Antacid:
Tab-500mg to 1.5g daily.
Liquid-5-15ml daily.
Laxative:
Tab-2.4-4.8g daily.
Liquid -30-60ml daily.
Schedule of Magnesium Hydroxide
N/A
Storage Requirements for Magnesium Hydroxide
Store it at room temperature (15-30 degree C) and away from excess heat and moisture.
Effects of Missed Dosage of Magnesium Hydroxide
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Magnesium Hydroxide
Give symptomatic and supportive treatment.

Sodium Bicarbonate

About Sodium Bicarbonate
Sodium compound, Systemic Antacid ,alkalinizer.
Mechanism of Action of Sodium Bicarbonate
Sodium bicarbonate in water dissociates to sodium (Na+) and bicarbonate (HCO3 -) ions. Sodium (Na+) is the principal cation of the extracellular fluid and it maintains fluid and electrolyte disturbances. Bicarbonate (HC03 -) is a normal constituent of body fluids. Plasma concentration is regulated by the kidney through acidification of the urine when there is a deficit or by alkalinization of the urine when there is an excess. Bicarbonate anion is considered ``labile`` since at a proper concentration of hydrogen ion (H+) it may be converted to carbonic acid (H2CO3) and hence to its volatile form, carbon dioxide (CO2) which is excreted by the lung.
Sodium bicarbonate can neutralize or reduce acids in the blood, or urine. It is also used in emergency medical situations (heart attacks, serious kidney or lung problems) to correct the normal acid-base balance in the blood or as an aid in treating overdoses with certain types of medications.Intravenous sodium bicarbonate therapy increases plasma bicarbonate, buffers excess hydrogen ion concentration, raises blood pH and reverses the clinical manifestations of acidosis.
Sodium bicarbonate is used in a serious condition called metabolic acidosis. This is when the acidity of blood and tissues is abnormally high. It arises when the body`s normal acid balancing mechanisms fail, for example, in cardiac arrest or severe kidney disease. Sodium bicarbonate neutralises the excess acid.
Pharmacokinets of Sodium Bicarbonate
Absorption: Sodium bicarbonate is well absorbed and reabsorbed after parenteral administration in ionized forms.
Excretion: Less than 1% is excreted in urine.
Onset of Action for Sodium Bicarbonate
N/A
Duration of Action for Sodium Bicarbonate
N/A
Half Life of Sodium Bicarbonate
N/A
Side Effects of Sodium Bicarbonate
1. Gastric disturbances
2. Belching
3. Flatulence
4. Hypernatraemia
5. Alkalosis
6. Pain at the site of injection
7. Venous irritation
8. Chemical cellulites
9. Ulceration
10. Tissue necrosis at the site of infiltration confusion
11. Swelling of the feet and legs
Contra-indications of Sodium Bicarbonate
1. Metabolic alkalosis
2. Respiratory alkalosis
3. Patients losing chlorides by vomiting or from continuous suction
4. Patient on diuretics which produces hypochloremic alkalosis
5. Hypocalcaemia in which alkalosis may produce tetany
6. Hypertension
7. Seizure
8. Heart failure
6. Hypernatreamia
Special Precautions while taking Sodium Bicarbonate
1. Renal impairment
2. Edema with sodium retention
3. Oliguria
4. Cushing`s syndrome
5. Dehydration
6. Heart problems
7. Hyperventilation
8. Low blood levels of calcium or potassium
9. Ulcers in the esophagus
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Sodium Bicarbonate
1. Metabolic acidosis
2. Severe diarrhoea
3. Urine alkalinization
Interactions for Sodium Bicarbonate
The renal clearance of the following agents may be :
a) increased - Chlorpropamide, lithium, methotrexate, salicylate, tetracycline.
b) decreased - Anorexients, quinidine, sympathomimetics.
Incompatibility : Avoid adding sodium bicarbonate to parenteral solution containing calcium, precipitation may result. Norepinephrine and dobutamine are incompatible.
Typical Dosage for Sodium Bicarbonate
Adult:
Parenteral
In cardiac arrest: 200 - 300 mEq of a 7.5 - 8.4 % solution as rapidly as possible and in emergency inject 300 - 500 ml of 5% solution.
Metabolic acidosis: 90 - 180 mEq/L as IV during first hour and then adjust the dose depending on patients response.
Urinary alkalization: 0.325 - 2 g in 3- 4 times daily for patients above 60 years maximum dose is 8g and in patients below 60 years is 17 g.
Children: 1 - 10 mEq/kg / day
Children up to two years of age: 1 mEq / kg IV bolus of 4.2% solution and dose may be repeated every 10 minutes. Maximum daily dose: 8 mEq/ kg
Schedule of Sodium Bicarbonate
N/A
Storage Requirements for Sodium Bicarbonate
Store at room temperature between 15 and 30 degrees C Do not freeze. Keep out of the reach of children
Effects of Missed Dosage of Sodium Bicarbonate
Do not apply
Effects of Overdose of Sodium Bicarbonate
Give supportive measures and symptomatic treatment. Correct the electrolyte balance. Ammonium chloride can be given in severe alkalosis.

Alginic Acid

About Alginic Acid
Naturally occurring hydrophilic colloidal polysaccharide, Protective agent against GERDs.
Mechanism of Action of Alginic Acid
This naturally occurring hydrophilic colloidal polysaccharide obtained from Sargassum Seaweeds reacts with saliva and produces a foamy froth that layers on the liquid in the stomach. Alginic acid powder swells when wetted with water. This may prevent reflux of acid into the esophagus by keeping the gastric contents in place and reduce the likelihood of reflux irritating the lining of the esophagus. The sodium calcium alginate fibres in haemostatic wound dressings absorbed by body fluids, as the calcium in the fiber is exchanged for sodium from the body fluids mixed salts of sodium and calcium alginate, and processed into non-woven fabric that is used in wound dressings. It binds with heavy metals and radioactive substances to its own molecules. It cannot be broken down by bile or saliva to be absorbed and secreted from the body together with heavy metals and radioactive substances.
Pharmacokinets of Alginic Acid
When ingested, almost all of the alginic acid remains undigested and is excreted either unchanged or as an alginate.
Onset of Action for Alginic Acid
N/A
Duration of Action for Alginic Acid
30 to 60 minutes
Half Life of Alginic Acid
N/A
Side Effects of Alginic Acid
1. Abdominal distension
2. Flatulence
3. Chalky taste in your mouth
4. Constipation
5. Diarrhea
6. Nausea
7. Vomiting.
Contra-indications of Alginic Acid
1. Hypersensitivity to the drug
2. Heart failure.
3. Renal failure.
Special Precautions while taking Alginic Acid
1.Allergies to medicines, foods, or other substances
2.Alzheimer disease
3.Appendicitis
4.Diarrhoea
5.Stomach blockage
6.Kidney problems
7.Liver problems
8.Ileostomy
9.Congestive heart failure
10.Decreased urination
11.Fluid retention
12.Rectal bleeding of unknown cause
13.Recently had stomach bleeding
14.Patient on low salt diet
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Alginic Acid
1. Heartburn (including heartburn of pregnancy)
2. Dyspepsia
3. Reflux oesophagitis
4. Hiatus hernia.
5. Protect inflamed areas near the entrance to the stomach (Sodium alginate)

Interactions for Alginic Acid
N/A
Typical Dosage for Alginic Acid
Take the drug as directed by the physician.
Schedule of Alginic Acid
N/A
Storage Requirements for Alginic Acid
Store below 25?C in a tightly closed container.
Effects of Missed Dosage of Alginic Acid
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Alginic Acid
Give symptomatic and supportive treatment.

Home Delivery for Aluminium Hydroxide + Magnesium Hydroxide + Sodium Bicarbonate + Alginic acid in Your City

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