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- Pharmacology For Diphenoxylate
DiphenoxylateAbout DiphenoxylateAn opioid agonist,Meperidine analogue, Antidiarrheals.Mechanism of Action of DiphenoxylateDiphenoxylate is an opioid agonist. It used for the treatment of diarrhea which acts by slowing down intestinal contractions.It is a Meperidine analogue that inhibits gastrointestinal motility locally and centrally.High doses it may produce opiate effect.Pharmacokinets of DiphenoxylateAbsorption:About 90% of the drug is absorbed.Distribution: It is distributed in milk. Metabolism:It undergoes metabolism in the liver.Excretion:It is excreted mainly in faeces and small amount in urine.Onset of Action for DiphenoxylateN/ADuration of Action for DiphenoxylateN/AHalf Life of DiphenoxylateN/ASide Effects of Diphenoxylate1.Sedation
Contra-indications of Diphenoxylate1.Hypersensitivity to Diphenoxylate
Special Precautions while taking Diphenoxylate1.Hepatic disease
4.Stop immediately if abdominal distension occurs
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with caution
Below 2 years:ContraindicatedIndications for Diphenoxylate1.Acute non specific diarrhoeaInteractions for DiphenoxylateN/ATypical Dosage for DiphenoxylateAdult:5 mg to be taken 4 times daily and adjust the dose as required.
2 - 5 years: 6 mg / day in 3 divided doses
5 - 8 years: 6 mg / day in 4 divided doses
8 - 12 years: 10mg / day in 5 divided doses
Schedule of DiphenoxylateHStorage Requirements for DiphenoxylateStore iat room temperature.Protect from heat and light.Keep out of the reach of children.Effects of Missed Dosage of DiphenoxylateTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Do not double the dose.Continue the regular schedule.Effects of Overdose of DiphenoxylateGive supportive measures and symptomatic treatment. Gastric lavage can be done to remove the drug from the body.If necessary a narcotic antagonist such as Naloxone may be given.
Home Delivery for Diphenoxylate in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including diphenoxylate.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for diphenoxylate and other medicines and health products. Home delivery services for diphenoxylate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take diphenoxylate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for diphenoxylate before they complete the sale. You can get this information while placing the order for diphenoxylate with the pharmacy.
Diphenoxylate is a generic medicine name and there are several brands available for it. Some of the brands for diphenoxylate might be better known than diphenoxylate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have diphenoxylate in stock, you can ask for one of the branded alternatives for diphenoxylate.