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- Pharmacology For Racecadotril
RacecadotrilAbout RacecadotrilA peripherally acting Enkephalinase inhibitor, Antidiarrheal.
Mechanism of Action of RacecadotrilRacecadotril is a dipeptide. It is an Enkephalinase inhibitor which prevents the degradation of Enkephalins. Enkephalins are endogenous opioid which act on delta opioid receptor and reduces the cyclic AMP level and produces antidiarrhoeal effect. Thus the increased concentration of Enkephalins reduces the hyper secretions of water and electrolyte in to the intestinal lumen. Racecadotril reduces the incidence of diarrhoea and diarrhoea associated symptoms.
Pharmacokinets of RacecadotrilAbsorption: Racecadotril is rapidly absorbed after oral administration.
Metabolism: It is rapidly metabolised by gastric enzyme lipase to active thiorphan metabolite.
Onset of Action for Racecadotril30 minutesDuration of Action for RacecadotrilN/AHalf Life of Racecadotril3 hoursSide Effects of Racecadotril1. Nausea
Contra-indications of Racecadotril1. Hypersensitivity to RacecadotrilSpecial Precautions while taking Racecadotril1. Renal insufficiency
2. Functional intestinal disorders
3. Dysenteric symptoms with bloody stools
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Racecadotril1. Acute symptomatic diarrhoeaInteractions for RacecadotrilNo clinically significant interactions involving interference with drug metabolism have been reported with Racecadotril.
Typical Dosage for RacecadotrilAdult: 300 mg/ day in 3 divided doses to be taken before meals.
Children: 4.5 mg / kg /day in 3 divided doses.
Schedule of RacecadotrilN/AStorage Requirements for RacecadotrilStore below 25 degree C. Protect from light and moisture.Effects of Missed Dosage of RacecadotrilTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of RacecadotrilGive supportive measures and symptomatic treatment.
Home Delivery for Racecadotril in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including racecadotril.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for racecadotril and other medicines and health products. Home delivery services for racecadotril may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take racecadotril only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for racecadotril before they complete the sale. You can get this information while placing the order for racecadotril with the pharmacy.
Racecadotril is a generic medicine name and there are several brands available for it. Some of the brands for racecadotril might be better known than racecadotril itself. If the pharmacy that's willing to deliver medicines to your home doesn't have racecadotril in stock, you can ask for one of the branded alternatives for racecadotril.