Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine Pharmacology

Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine

About Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Mechanism of Action of Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Pharmacokinets of Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Onset of Action for Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Duration of Action for Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Half Life of Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Side Effects of Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Contra-indications of Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Special Precautions while taking Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Interactions for Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Typical Dosage for Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
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Schedule of Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Storage Requirements for Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Effects of Missed Dosage of Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A
Effects of Overdose of Diastase + Pepsin + Vitamin B-Complex + Cyproheptadine
N/A

Diastase

About Diastase
A soluble, nitrogenous ferment .A mixture of starch-hydrolyzing enzymes from malt , converts starch to dextrin and maltose, Pancreatic insufficiency.
Mechanism of Action of Diastase
N/A
Pharmacokinets of Diastase
N/A
Onset of Action for Diastase
N/A
Duration of Action for Diastase
N/A
Half Life of Diastase
N/A
Side Effects of Diastase
N/A
Contra-indications of Diastase
N/A
Special Precautions while taking Diastase
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Diastase
1.Pancreatic insufficiency
Interactions for Diastase
N/A
Typical Dosage for Diastase
As directed by the Physician
Schedule of Diastase
N/A
Storage Requirements for Diastase
Store the medicine in the tightly closed container. Keep out of the reach of children. Store it at room temperature and away from excess heat and moisture.
Effects of Missed Dosage of Diastase
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose
Effects of Overdose of Diastase
N/A

Pepsin

About Pepsin
A digestive protease, A digestive aid.
Mechanism of Action of Pepsin
N/A
Pharmacokinets of Pepsin
N/A
Onset of Action for Pepsin
N/A
Duration of Action for Pepsin
N/A
Half Life of Pepsin
N/A
Side Effects of Pepsin
N/A
Contra-indications of Pepsin
N/A
Special Precautions while taking Pepsin
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Pepsin
1.Improve blood circulation
2.Prevent abnormal blood clotting.
3.Reduce pain and inflammation associated with Phlebitis.
4.Alleviate the pain, inflammation, and discomfort of varicose veins.
5.Minimize muscle pain that occurs after exercise.
6.Minimize the inflammation and pain associated with Osteoarthritis and Rheumatoid Arthritis.
7.Alleviate the symptoms of Sinusitis.
8.Alleviate oedema.
Interactions for Pepsin
N/A
Typical Dosage for Pepsin
N/A
Schedule of Pepsin
N/A
Storage Requirements for Pepsin
Store in a cool, dry place, away from direct heat and light. Keep all medicines out of the reach of children.
Effects of Missed Dosage of Pepsin
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Pepsin
Give symptomatic and supportive treatment.

Vitamin B-Complex

About Vitamin B-Complex
Vitamin B-complex are group of vitamins, which include Thiamine (B1),Riboflavin (B2),Niacin (B3),Pantothenic acid (B5),Pyridoxine (B6),Cyanocobalamin (B12),Folic acid and Biotin.
These vitamins are essential for the breakdown of carbohydrates into glucose (this provides energy for the body),the breakdown of fats and proteins (which aids the normal functioning of the nervous system),muscle tone in the stomach and intestinal tract,Skin,Hair,Eyes,Mouth and Liver
Mechanism of Action of Vitamin B-Complex
N/A
Pharmacokinets of Vitamin B-Complex
N/A
Onset of Action for Vitamin B-Complex
N/A
Duration of Action for Vitamin B-Complex
N/A
Half Life of Vitamin B-Complex
N/A
Side Effects of Vitamin B-Complex
1.Drowsiness
2.Headache
3.Diarrhoea
4.Nausea.
5.Numbness of the skin
Contra-indications of Vitamin B-Complex
Hypersensitivity to the ingredient of Vitamin B-complex
Special Precautions while taking Vitamin B-Complex
1.Pernecious anaemia
2.Patient receiving dialysis
Pregnancy Related Information
May be used.
Old Age Related Information
May be used.
Breast Feeding Related Information
May be used.
Children Related Information
May be used.
Indications for Vitamin B-Complex
1.Vitamin deficiency states
2. As an adjuvant to antibiotic therapy
3. Combinations with lactobacillus are indicated in aphthous stomatitis, thrush.
Interactions for Vitamin B-Complex
Sulfinpyrazone: Uricosuric effect of sulfinpyrazone may be inhibited by niacin.
Levodopa: Pyridoxine reduces efficacy of levodopa. Avoid supplemental vitamins that contain greater then 5 mg pyridoxine in the daily dose.
Phenobarbital: Serum levels of Phenobarbital may be decreased if used concomitantly with pyridoxine.
Phenytoin: Pyridoxine decreases serum levels of phenytoin.
Dapsone: PABA antagonizes anti-malarial effect of dapsone.
Typical Dosage for Vitamin B-Complex
I tablet /day
Schedule of Vitamin B-Complex
N/A
Storage Requirements for Vitamin B-Complex
Store at room temperature. Keep out of the reach of children.Protect from heat, light and moisture.
Effects of Missed Dosage of Vitamin B-Complex
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vitamin B-Complex
Give supportive measures and symptomatic treatment.

Cyproheptadine

About Cyproheptadine
Piperidine (nonselective) First Generation H1 Antagonist ,anticholinergic and antiserotonergic(5-HT2 receptor antagonist), antihistaminic,appetite stimulant.
Mechanism of Action of Cyproheptadine
Cyproheptadine is a sedative antihistamine with serotonin antagonist, and calcium-channel blocking actions. It competes with Histamine for H1 receptors present in the smooth muscle of gastrointestinal tract, bronchi, large blood vessels and uterus. Histamine cannot bind with H1 receptors and cannot produce histamine induced allergic symptoms. Cyproheptadine blocks serotonin receptors preferentially block 5HT2A receptor and are useful in migraine prophylaxis. It has weak anticholinergic activity and possesses mild CNS depressant properties. It also blocks voltage sensitive calcium channel in islet of pancreas and smooth muscle. Cyproheptadine increases appetite and cause weight gain.
Pharmacokinets of Cyproheptadine
Absorption: Cyproheptadine is well absorbed after oral administration. Distribution: It is distributed in the body in highly protein bound form. Metabolism: It is extensively metabolised in the liver. Excretion: Metabolites are excreted primarily in the urine; unchanged drug and small amount of metabolites are excreted through faeces.
Onset of Action for Cyproheptadine
15 - 60 minutes
Duration of Action for Cyproheptadine
N/A
Half Life of Cyproheptadine
1 - 4 hours
Side Effects of Cyproheptadine
1.Dizziness
2.Drowsiness
3.Fatigue
4.Nervousness
5.Sleepiness
6.Epigastric distress
7.Dry mouth
8.Nausea
9.Vomiting
10.Rash
11.Urine retention
12.Weight gain


Contra-indications of Cyproheptadine
1.Hypersensitivity to Cyproheptadine and other drugs of similar structure
2.Angle closure glaucoma
3.Acute asthma
4.Peptic ulcer
5.Bladder neck obstruction
6.Prostatic hyperplasia
7.Pyloroduodenal obstruction
8.Debilitated patients
9.Patient on monoamine oxidase inhibitory therapy.
Special Precautions while taking Cyproheptadine
1.Hypertension
2.Hyperthyroidism
3.Increased intraocular pressure
4.Bronchial asthma
5.Patient should be cautioned against activities requiring mental alertness such as driving, operating machine or involving in any hazardous activities 6.Avoid alcohol


Pregnancy Related Information
Use with caution
Old Age Related Information
Contraindicated.
Breast Feeding Related Information
Contraindicated.
Children Related Information
Use with caution
NEONATES: contraindicated
Indications for Cyproheptadine
1.Antiallergic
2.Appetite stimulant
3.Cluster headache
Interactions for Cyproheptadine
Alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, anti-anxiety drugs, narcotic analgesics): CNS depressant action potentiated.
MAOIs, tricylic antidepressants and atropine: Antimuscarinic action potentiated.
Aminoglycosides: Ototoxicity produced by aminoglycosides masked.

Typical Dosage for Cyproheptadine
Adult: 12 - 16 mg / day in 3 - 4 divided doses.
Maximum dose: 32 mg / day
Migraine prophylaxis and vascular headaches: Initial dose: 4 mg and may be repeated after 30 minutes; A maintenance dose of 4 mg may be given every 4 to 6 hours.

Children above 6 years: 8 - 12 mg / day in 2 - 3 divided doses
Maximum dose: 16 mg / day
Children 2 - 6: 4 - 6 mg / day in 2 - 3 divided doses
Maximum dose: 12 mg / day
Schedule of Cyproheptadine
G
Storage Requirements for Cyproheptadine
Store at room temperature in a tightly closed container.
Effects of Missed Dosage of Cyproheptadine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Cyproheptadine
Give supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing vomiting. Absorption of the drug can be reduced by administration of activated charcoal. Hypotension can be treated by vasopressors and seizure with Diazepam or Phenytoin.

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