Sufentanil Citrate Pharmacology

Sufentanil Citrate

About Sufentanil Citrate
Opioid, Anilidopiperidine , Narcotic Analgesic, General Anesthetic.
Mechanism of Action of Sufentanil Citrate
This Fentanyl congener has agonistic action on the mu Opioid receptors present in the CNS. This produce analgesic effect. This drug also produces depression on CNS.
Pharmacokinets of Sufentanil Citrate
Absorption-Rapidly absorbed after intravenous administration.
Distribution-Widely distributed in the body due to its lipophilic character. It cross the blood brain barrier.90% bound to the plasma proteins.
Metabolism- Metabolized mainly in liver and in small intestine.
Excretion- It is excreted as unchanged form and its metabolites via urine.
Onset of Action for Sufentanil Citrate
1 min after intravenous administration
Duration of Action for Sufentanil Citrate
5 minutes
Half Life of Sufentanil Citrate
3 hrs
Side Effects of Sufentanil Citrate
1. Bradycardia
2. Vasodialatation
3. Nausea
4. Vomiting
5. Blurred vision
6. Respiratory depression
7. Addiction
8. Somnolence
9. Hypotension
10. Intra operative muscle movement
11. Chest wall rigidity
12. Apnea
13. Bronchospasm
14. Pruritus
15. Erythema
Contra-indications of Sufentanil Citrate
1.Hypersensitivity to this drug.
Special Precautions while taking Sufentanil Citrate
1. Decreased respiratory deserve
2. Head injuries
3. Renal diseases
4. Pulmonary diseases
5. Hepatic diseases
6. Mono Amino Oxydase inhibitors dependant
Pregnancy Related Information
May be used
Old Age Related Information
Reduced dose given to the patient
Breast Feeding Related Information
May be used
Children Related Information
Cautiously used
Indications for Sufentanil Citrate
1. Anesthetic
2. Pain management
Interactions for Sufentanil Citrate
CNS / respiratory depressants.
Typical Dosage for Sufentanil Citrate
0.5 to 8 mcg/kg as initial dose.
10 to 50 mcg/kg as maintenance dose.
10 to 25 mcg/kg as initial dose.
5 to 50 mcg/kg as maintenance dose.
Schedule of Sufentanil Citrate
Storage Requirements for Sufentanil Citrate
Stored at 4 degree Celsius.
Effects of Missed Dosage of Sufentanil Citrate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Sufentanil Citrate
Give symptomatic and supportive treatment.Establish artificial respiratory exchange. Administer an antagonist e.g.Naloxone if there is respiratory or cardiac depression . Monitor laboratory parameters, vital signs and neurological status closely.

Home Delivery for Sufentanil Citrate in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including sufentanil citrate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sufentanil citrate and other medicines and health products. Home delivery services for sufentanil citrate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take sufentanil citrate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sufentanil citrate before they complete the sale. You can get this information while placing the order for sufentanil citrate with the pharmacy.

Sufentanil Citrate is a generic medicine name and there are several brands available for it. Some of the brands for sufentanil citrate might be better known than sufentanil citrate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sufentanil citrate in stock, you can ask for one of the branded alternatives for sufentanil citrate.