- Medicine India
- Generic Medicines
- Pharmacology For Tricholine citrate + Cyproheptadine
Tricholine citrate + Cyproheptadine Pharmacology
Tricholine citrate + CyproheptadineAbout Tricholine citrate + CyproheptadineN/AMechanism of Action of Tricholine citrate + CyproheptadineN/APharmacokinets of Tricholine citrate + CyproheptadineN/AOnset of Action for Tricholine citrate + CyproheptadineN/ADuration of Action for Tricholine citrate + CyproheptadineN/AHalf Life of Tricholine citrate + CyproheptadineN/ASide Effects of Tricholine citrate + CyproheptadineN/AContra-indications of Tricholine citrate + CyproheptadineN/ASpecial Precautions while taking Tricholine citrate + CyproheptadineN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Tricholine citrate + CyproheptadineN/AInteractions for Tricholine citrate + CyproheptadineN/ATypical Dosage for Tricholine citrate + CyproheptadineN/ASchedule of Tricholine citrate + CyproheptadineN/AStorage Requirements for Tricholine citrate + CyproheptadineN/AEffects of Missed Dosage of Tricholine citrate + CyproheptadineN/AEffects of Overdose of Tricholine citrate + CyproheptadineN/A
Tricholine citrateAbout Tricholine citrateA quaternary ammonium compound, Used in liver disorders.Mechanism of Action of Tricholine citrateTricholine citrate contains three molecules of choline. Due to choline`s lipotropic action, it is useful in the treatment of fatty infiltration and cirrhosis of liver. Choline converts fat into phospholipids like, lecithin, which is essential to biomembrane structure and its function. Lecithin is also a major component of high density lipoprotein (HDL), and is used to mobilize cholesterol from cell membrane. In patients with fatty liver, increased rate of phospholipid turnover has been observed following administration of choline.Pharmacokinets of Tricholine citrateN/AOnset of Action for Tricholine citrateN/ADuration of Action for Tricholine citrateN/AHalf Life of Tricholine citrateN/ASide Effects of Tricholine citrateN/AContra-indications of Tricholine citrate1.Hypersensitivity to Tricholine citrateSpecial Precautions while taking Tricholine citrateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Tricholine citrate1.Liver disordersInteractions for Tricholine citrateN/ATypical Dosage for Tricholine citrateN/ASchedule of Tricholine citrateN/AStorage Requirements for Tricholine citrateN/AEffects of Missed Dosage of Tricholine citrateN/AEffects of Overdose of Tricholine citrateN/A
CyproheptadineAbout CyproheptadinePiperidine (nonselective) First Generation H1 Antagonist ,anticholinergic and antiserotonergic(5-HT2 receptor antagonist), antihistaminic,appetite stimulant.Mechanism of Action of CyproheptadineCyproheptadine is a sedative antihistamine with serotonin antagonist, and calcium-channel blocking actions. It competes with Histamine for H1 receptors present in the smooth muscle of gastrointestinal tract, bronchi, large blood vessels and uterus. Histamine cannot bind with H1 receptors and cannot produce histamine induced allergic symptoms. Cyproheptadine blocks serotonin receptors preferentially block 5HT2A receptor and are useful in migraine prophylaxis. It has weak anticholinergic activity and possesses mild CNS depressant properties. It also blocks voltage sensitive calcium channel in islet of pancreas and smooth muscle. Cyproheptadine increases appetite and cause weight gain.Pharmacokinets of CyproheptadineAbsorption: Cyproheptadine is well absorbed after oral administration. Distribution: It is distributed in the body in highly protein bound form. Metabolism: It is extensively metabolised in the liver. Excretion: Metabolites are excreted primarily in the urine; unchanged drug and small amount of metabolites are excreted through faeces.Onset of Action for Cyproheptadine15 - 60 minutesDuration of Action for CyproheptadineN/AHalf Life of Cyproheptadine1 - 4 hoursSide Effects of Cyproheptadine1.Dizziness
Contra-indications of Cyproheptadine1.Hypersensitivity to Cyproheptadine and other drugs of similar structure
2.Angle closure glaucoma
5.Bladder neck obstruction
9.Patient on monoamine oxidase inhibitory therapy.
Special Precautions while taking Cyproheptadine1.Hypertension
3.Increased intraocular pressure
5.Patient should be cautioned against activities requiring mental alertness such as driving, operating machine or involving in any hazardous activities 6.Avoid alcohol
Pregnancy Related InformationUse with cautionOld Age Related InformationContraindicated.Breast Feeding Related InformationContraindicated.Children Related InformationUse with caution
Indications for Cyproheptadine1.Antiallergic
Interactions for CyproheptadineAlcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, anti-anxiety drugs, narcotic analgesics): CNS depressant action potentiated.
MAOIs, tricylic antidepressants and atropine: Antimuscarinic action potentiated.
Aminoglycosides: Ototoxicity produced by aminoglycosides masked.
Typical Dosage for CyproheptadineAdult: 12 - 16 mg / day in 3 - 4 divided doses.
Maximum dose: 32 mg / day
Migraine prophylaxis and vascular headaches: Initial dose: 4 mg and may be repeated after 30 minutes; A maintenance dose of 4 mg may be given every 4 to 6 hours.
Children above 6 years: 8 - 12 mg / day in 2 - 3 divided doses
Maximum dose: 16 mg / day
Children 2 - 6: 4 - 6 mg / day in 2 - 3 divided doses
Maximum dose: 12 mg / day
Schedule of CyproheptadineGStorage Requirements for CyproheptadineStore at room temperature in a tightly closed container.Effects of Missed Dosage of CyproheptadineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CyproheptadineGive supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing vomiting. Absorption of the drug can be reduced by administration of activated charcoal. Hypotension can be treated by vasopressors and seizure with Diazepam or Phenytoin.
Home Delivery for Tricholine citrate + Cyproheptadine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including tricholine citrate + cyproheptadine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for tricholine citrate + cyproheptadine and other medicines and health products. Home delivery services for tricholine citrate + cyproheptadine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take tricholine citrate + cyproheptadine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for tricholine citrate + cyproheptadine before they complete the sale. You can get this information while placing the order for tricholine citrate + cyproheptadine with the pharmacy.
Tricholine citrate + Cyproheptadine is a generic medicine name and there are several brands available for it. Some of the brands for tricholine citrate + cyproheptadine might be better known than tricholine citrate + cyproheptadine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have tricholine citrate + cyproheptadine in stock, you can ask for one of the branded alternatives for tricholine citrate + cyproheptadine.