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- Pharmacology For L-Ornithine L-Aspartate + Vit B2 + Vit B3
L-Ornithine L-Aspartate + Vit B2 + Vit B3 Pharmacology
L-Ornithine L-Aspartate + Vit B2 + Vit B3
About L-Ornithine L-Aspartate + Vit B2 + Vit B3N/AMechanism of Action of L-Ornithine L-Aspartate + Vit B2 + Vit B3N/APharmacokinets of L-Ornithine L-Aspartate + Vit B2 + Vit B3N/AOnset of Action for L-Ornithine L-Aspartate + Vit B2 + Vit B3N/ADuration of Action for L-Ornithine L-Aspartate + Vit B2 + Vit B3N/AHalf Life of L-Ornithine L-Aspartate + Vit B2 + Vit B3N/ASide Effects of L-Ornithine L-Aspartate + Vit B2 + Vit B3N/AContra-indications of L-Ornithine L-Aspartate + Vit B2 + Vit B3N/ASpecial Precautions while taking L-Ornithine L-Aspartate + Vit B2 + Vit B3N/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for L-Ornithine L-Aspartate + Vit B2 + Vit B3N/AInteractions for L-Ornithine L-Aspartate + Vit B2 + Vit B3N/ATypical Dosage for L-Ornithine L-Aspartate + Vit B2 + Vit B3N/ASchedule of L-Ornithine L-Aspartate + Vit B2 + Vit B3N/AStorage Requirements for L-Ornithine L-Aspartate + Vit B2 + Vit B3N/AEffects of Missed Dosage of L-Ornithine L-Aspartate + Vit B2 + Vit B3N/AEffects of Overdose of L-Ornithine L-Aspartate + Vit B2 + Vit B3N/AL-Ornithine L-Aspartate
About L-Ornithine L-AspartateA dietary supplement, a Hepatobiliary preparation., In Hepatic dysfunction.Mechanism of Action of L-Ornithine L-AspartateL-Ornithine L-Aspartate is a stable salt of Ornithine and aspartic acid. Ornithine and Aspartate are the substrate in the metabolic conversion of ammonia to urea and glutamate respectively. LOLA increases ammonia detoxification and decreases ammonia level in the blood and useful in patient with hepatic encephalopathy. It is also involved in the Krebs cycle and it is helpful in energy production.Pharmacokinets of L-Ornithine L-AspartateN/AOnset of Action for L-Ornithine L-AspartateN/ADuration of Action for L-Ornithine L-AspartateN/AHalf Life of L-Ornithine L-AspartateN/ASide Effects of L-Ornithine L-Aspartate1.Transient nausea
2.Vomiting
Contra-indications of L-Ornithine L-AspartatePatient with creatinine level more than 3 mg / 100 mlSpecial Precautions while taking L-Ornithine L-AspartateN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for L-Ornithine L-Aspartate1.Acute and chronic hepatitis
2.Cirrhosis of liver
3.Alcoholic liver damage
4.Adjunct to hepatotoxic drugs
5.Hepatocellular insufficiency- stimulus for glutamine synthesis
Interactions for L-Ornithine L-AspartateN/ATypical Dosage for L-Ornithine L-AspartateORAL
Adult: 1 - 2tablets 3 times daily each tablet contain 150 mg of L-Ornithine L-aspartate
Schedule of L-Ornithine L-AspartateN/AStorage Requirements for L-Ornithine L-AspartateStore at room temperatureEffects of Missed Dosage of L-Ornithine L-AspartateTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of L-Ornithine L-AspartateGive supportive measures and symptomatic treatment.Vit B2
About Vit B2N/AMechanism of Action of Vit B2Riboflavin exerts it`s action by influencing metabolic reactions. Riboflavin functions in the forms of flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) which are coenzymes for flavoproteins involved in many oxidation-reduction reactions. Both FMN and FAD play a vital metabolic role in numerous tissue respiration systems. Riboflavin also directly involves in maintaining erythrocyte integrity.Pharmacokinets of Vit B2Absorption: Well absorbed orally; bioavailability increases when administer along with food.
Distribution: Widely distributed in the tissues and limited amount is stored in the liver, spleen, kidneys, and heart. It crosses the placenta and also secreted in to the breast milk.
Metabolism: Phosphorylated in the intestine, liver and other tissues to FMN and metabolized in to FAD the liver.
Excretion: Larger doses are excreted unchanged in urine.
Onset of Action for Vit B2N/ADuration of Action for Vit B2N/AHalf Life of Vit B266 to 84 minutesSide Effects of Vit B21. Bright yellow urine with higher dosesContra-indications of Vit B2No known contraindications.Special Precautions while taking Vit B2N/APregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be usedIndications for Vit B21. Ariboflavinosis
2. Arteriosclerosis
3. Hypertension
4. Obesity
5. Diabetis
6. Cholepathy
7. Glossitis
8. Stomatitis
9. Dermatitis of trunk and extremities
10. Other riboflavin deficiency symptoms
Interactions for Vit B2Oral contraceptive:Dose of Riboflavin may need to be increased
Propantheline Bromide:Delays absorption rate of Riboflavin
Typical Dosage for Vit B2Oral:
Adults: 20 to 40mg three times daily or depending up on the severity.
Children: 20mg daily.
Riboflavin deficiency:
Adults and children over 12 years: 5 to 30mg/day depending up on the severity .
Children (below 12years): 3 to 10mg/day depending up on the severity.
Schedule of Vit B2C1Storage Requirements for Vit B2Store in a well closed container; in a cool place and protect from light.Effects of Missed Dosage of Vit B2Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the doseEffects of Overdose of Vit B2Provide symptomatic treatment and supportive measures.Vit B3
About Vit B3N/AMechanism of Action of Vit B3Niacin refers to Nicotinic acid as well as Nicotinamide which exerts it`s action by influencing metabolic reactions. It is converted in to coenzymes Ncotinamide adenine dinucleotide (NAD) and it`s phosphate Ncotinamide adenine dinucleotide phosphate (NADP) involved in oxidation reduction reactions. These pyridine nucleotides act as hydrogen acceptors in the electron transport chain in tissue respiration, glycolysis, and fat synthesis. Nicotinic acid in high doses has vasodilator effects and also improves lipid profile; reduces serum cholesterol, raises HDL level, lowers VLDL, and LDL levels.Pharmacokinets of Vit B3Absorption: Well absorbed orally, Distribution: Widely distributed in the body, and also secreted in to breast milk, Modest amounts are stored in liver, Metabolism: Metabolized in to active metabolites in liver, Excretion: Extra drug is excreted through urine.Onset of Action for Vit B3N/ADuration of Action for Vit B3N/AHalf Life of Vit B3N/ASide Effects of Vit B31. Flushing
2. Activation of peptic ulcer
3. Nausea
4. Vomiting
5. Diarrhoea
6. Headache
7. Rashes
8. Pruritus
9. Hypotension
10. Arrhythmias
11. Hepatic impairment
Contra-indications of Vit B31. Hypersensitivity to the drug
2. Hepatic impairment
3. Peptic ulcer
4. Severe hypotension
5. Arterial haemorrhage
Special Precautions while taking Vit B31.History of liver disease
2.Gall bladder diseases
3.Gout
4.Coronary artery diseases
5.Diabetes mellitus
6.When use along with Statins reduces the dosage of StatinsPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Vit B31. Pellagra
2. Niacin deficiency
3. Hartnup disease
4. Hyperlipidaemia (only nicotinic acid
5. Peripheral vascular diseases (only nicotinic acid)Interactions for Vit B3Aspirin: May decrease the metabolic clearance of nicotinic acid
Sympathetic blocking agent: May cause added vasodilation and hypotension
Isoniazid: may deplete levels of niacin and cause deficiency.
Typical Dosage for Vit B3Oral:
Pellagra: 200 to 500mg daily in divided doses
Prophylactically: 20 to 50mg daily.
Dietary supplement: 10 to 20mg daily
Peripheral vascular diseases (only nicotinic acid): 100 to 150mg three to five times daily. Alternatively 1000 to 2000g once daily at bed time.
Hyperlipidaemia (only nicotinic acid): 1.5 to 6g daily in two to four divided doses with or after meals.
Hartnup disease: 50 to 200mg daily in divided doses.
Schedule of Vit B3C1Storage Requirements for Vit B3Store at controlled room temperature at a range of 15 to 30 degree CEffects of Missed Dosage of Vit B3Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vit B3Provide supportive measures and symptomatic treatmentHome Delivery for L-Ornithine L-Aspartate + Vit B2 + Vit B3 in Your City
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L-Ornithine L-Aspartate + Vit B2 + Vit B3 is a generic medicine name and there are several brands available for it. Some of the brands for l-ornithine l-aspartate + vit b2 + vit b3 might be better known than l-ornithine l-aspartate + vit b2 + vit b3 itself. If the pharmacy that's willing to deliver medicines to your home doesn't have l-ornithine l-aspartate + vit b2 + vit b3 in stock, you can ask for one of the branded alternatives for l-ornithine l-aspartate + vit b2 + vit b3.
