Sevelamer Pharmacology

Sevelamer

About Sevelamer
Phosphate Binder, Management of hyperphosphataemia,urinary alkalinizer.
Mechanism of Action of Sevelamer
Sevelamer is a phosphate binder. It is used to reduce the level of phosphorus in chronic renal disease. It binds with phosphate in the gastrointestinal tract and decreases phosphate absorption.
These amines (Sevelamer) exist in a protonated form in the intestine and interact with phosphate molecules. It binds with phosphate in the dietary tract and decreases absorption. Sevelamer lowers the phosphate concentration in the serum.
Pharmacokinets of Sevelamer
Excretion: It is excreted mainly in through faeces
Onset of Action for Sevelamer
N/A
Duration of Action for Sevelamer
N/A
Half Life of Sevelamer
N/A
Side Effects of Sevelamer
1.Nausea
2.Upset stomach
3.Diarrhoea
4.Vomiting
5.Dyspepsia
6.Flatulence
7.Constipation
8.Headache
9.Cough
10.Abdominal Pain
11.Hypotension
12.Dizziness
13.Dyspnoea
14.Thrombosis
15.Peripheral oedema
16.Leg cramps
17.Hypertension
18.Pruritus

Contra-indications of Sevelamer
1.Hypersensitivity to Sevelamer.
2.Hypophosphataemia
3.Bowel obstruction
Special Precautions while taking Sevelamer
1.Swallowing disorders
2.Gastrointestinal motility disorders
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Contraindicated
Indications for Sevelamer
Hyperphosphataemia in chronic kidney disease
Interactions for Sevelamer
N/A
Typical Dosage for Sevelamer
Adult: 800 to 1600 mg / day in divided doses.
Schedule of Sevelamer
N/A
Storage Requirements for Sevelamer
Store at room temperature. Keep away from heat, light and moisture .Keep out of the reach of children.
Effects of Missed Dosage of Sevelamer
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Sevelamer
Give supportive measures and symptomatic treatment

Home Delivery for Sevelamer in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including sevelamer.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sevelamer and other medicines and health products. Home delivery services for sevelamer may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take sevelamer only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sevelamer before they complete the sale. You can get this information while placing the order for sevelamer with the pharmacy.

Sevelamer is a generic medicine name and there are several brands available for it. Some of the brands for sevelamer might be better known than sevelamer itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sevelamer in stock, you can ask for one of the branded alternatives for sevelamer.