Phenazopyridine Pharmacology

Phenazopyridine

About Phenazopyridine
Azo dye, Nonopioid analgesic, Urinary Analgesic, Interstitial cystitis agent.
Mechanism of Action of Phenazopyridine
Phenazopyridine is a urinary analgesic. The relief of discomfort is mostly attributed by its local anaesthetic action rather than antibacterial action. It exerts a topical analgesic effect on the urinary tract mucous and provides symptomatic relief of burning, urgency, frequency, pain, and other discomforts arising from irritation of the lower urinary tract caused by infection, trauma, surgery, endoscopic procedures, or the passage of catheters. Its analgesic action may reduce the need for systemic analgesics. It is used solely for relief of symptoms
Pharmacokinets of Phenazopyridine
Distribution: Small amount of the drug enter the cerebrospinal fluid and cross the placenta.
Metabolism: It is extensively metabolised in the liver.
Excretion: Drug is excreted primarily in the urine.
Onset of Action for Phenazopyridine
N/A
Duration of Action for Phenazopyridine
N/A
Half Life of Phenazopyridine
N/A
Side Effects of Phenazopyridine
1. Nausea
2. Gastric disturbances
3. Headache
4. Haemolytic anaemia
5. Methhaemoglobinemia
6. Rash
7. Pruritis
8. Jaundice
9. Orange to red colour of the urine
Contra-indications of Phenazopyridine
1. Hypersensitivity to Phenazopyridine
2. Glomerulonephritis
3. Severe hepatitis
4. Uremia
5. Pyelonephritis during pregnancy
6. Renal impairment
Special Precautions while taking Phenazopyridine
1.Gastric disturbances
2.Avoid use of contact lenses
3.Avoid driving vehicle, operating machine and other works which require mental illness.
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution.
Breast Feeding Related Information
Use with caution.
Children Related Information
May be used
NEONATES: contraindicated
Indications for Phenazopyridine
1. Pain, burning and discomfort of the urinary tract
Interactions for Phenazopyridine
Lab tests: May interfere with urinalysis based on spectrometry or color reaction.
Typical Dosage for Phenazopyridine
Adult: 200 mg 3 times daily should be taken after meals.
Children: 12 mg / kg body weight / day in 3 divided doses
Schedule of Phenazopyridine
N/A
Storage Requirements for Phenazopyridine
Store at room temperature. Protect from heat and moisture. Keep out of the reach of children
Effects of Missed Dosage of Phenazopyridine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Phenazopyridine
Give supportive measures and symptomatic treatment.

Home Delivery for Phenazopyridine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including phenazopyridine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for phenazopyridine and other medicines and health products. Home delivery services for phenazopyridine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take phenazopyridine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for phenazopyridine before they complete the sale. You can get this information while placing the order for phenazopyridine with the pharmacy.

Phenazopyridine is a generic medicine name and there are several brands available for it. Some of the brands for phenazopyridine might be better known than phenazopyridine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have phenazopyridine in stock, you can ask for one of the branded alternatives for phenazopyridine.