Apomorphine Pharmacology

Apomorphine

About Apomorphine
Potent dopamine agonist, Anti-Parkinson`s Agent.
Mechanism of Action of Apomorphine
Apomorphine is a potent dopamine agonist. It is useful in advanced disease for patients experiencing unpredictable off periods with Levodopa treatment.
Pharmacokinets of Apomorphine
Absorption: It is well absorbed after subcutaneous administration.
Distribution: It is widely distributed in the body.
Onset of Action for Apomorphine
N/A
Duration of Action for Apomorphine
N/A
Half Life of Apomorphine
30 - 60 minutes
Side Effects of Apomorphine

1.Nausea
2.Vomiting
3.Diarrhoea
4.Dyskinesia
5.Weakness
6.Dizziness
7.Confusion
8.Hallucinations
9.Constipation
10.Yawning
11.Drowsiness
12.Somnolence
13.Postural Hypotension
14.Rhinorrhea
15.Chest Pain
16.Edema
17.Swelling of Extremities
18.Arthralgia
19.Insomnia
20.Sedation
21.Euphoria
22.Light headedness
23.Restlessness
24.Tremor
25.Headache
26.Depression
27.Urinary tract infection
28.Anxiety
29.Congestive heart failure
30.Limb pain
31.Back pain
32.Pneumonia
33.Increased sweating
34.Dyspnea
35.Fatigue
36.Dehydration.
Contra-indications of Apomorphine
1.Hypersensitivity to Apomorphine
2.Respiratory depression
3.CNS depression
4.Hepatic Impairment
5.Neuropsychiatric problems
6.Dementia
7.Severe dyskinesia
8.Hypotonia
Special Precautions while taking Apomorphine
1.Renal Impairment
2.Pulmonary dysfunction
3.Cardiovascular diseases
4.Endocrine diseases
5.Hypotension
6.Dyskinesias
7.Fibrotic Complications
8.Priapism
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Contraindicated
Indications for Apomorphine
1. "Off" episodes associated with advanced Parkinsons disease
Interactions for Apomorphine
N/A
Typical Dosage for Apomorphine
Subcutaneous: 3 - 30mg/day in divided doses depending on the response.
Maximum dose: 100mg
Schedule of Apomorphine
N/A
Storage Requirements for Apomorphine
Store at room temperature. Keep out of the reach of children.
Effects of Missed Dosage of Apomorphine
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Apomorphine
Give supportive measures and symptomatic treatment.

Home Delivery for Apomorphine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including apomorphine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for apomorphine and other medicines and health products. Home delivery services for apomorphine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take apomorphine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for apomorphine before they complete the sale. You can get this information while placing the order for apomorphine with the pharmacy.

Apomorphine is a generic medicine name and there are several brands available for it. Some of the brands for apomorphine might be better known than apomorphine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have apomorphine in stock, you can ask for one of the branded alternatives for apomorphine.