- Medicine India
- Generic Medicines
- Pharmacology For Phenformin
PhenforminAbout PhenforminBiguanide derivative ,Insulin Sensitizer, Oral Anti-diabetic.Mechanism of Action of PhenforminIt is a biguanide which exerts antidiabetic action. The drug suppresses gluconeogenesis in liver and thus suppresses hepatic glucose output. It enhance insulin mediated glucose disposal in muscle and adipose tissue. It enhance GLUT1 (glucose transporter-1) transport from intracellular site to plasma membrane. It also interferes with respiratory chain in mitochondria and promotes peripheral glucose utilization by increasing anaerobic glycolysis. It inhibits intestinal absorption of glucose, other hexose sugars, amino acids and vitamin B12.
Pharmacokinets of PhenforminAbsorption: Incompletely but adequately absorbed orally, Excretion: Excreted through faeces and urine.
Onset of Action for PhenforminN/ADuration of Action for Phenformin8 to 12 hoursHalf Life of Phenformin3 to 10 hoursSide Effects of Phenformin1. Abdominal pain
5. Metalic taste
6. Mild diarrhea
8. Lactic acidosis
Contra-indications of Phenformin1. Hypersensitivity to the drug
2. Renal impairment
3. Hepatic impairment
4. Diabetic ketoacidosis
5. Cardiovascular collapse
6. Hypotensive states
7. Respiratory disease
Special Precautions while taking Phenformin1. Alcohol intake can precipitate severe lactic acidosis
2. Vitamin B12deficiency
3. In malnourished and deliberate individuals
4. Adrenal insufficiency
5. Pituitary insufficiency.
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationContraindicated
Indications for Phenformin1.Non insulin dependent diabetes mellitus (as adjunct to diet and exercise)Interactions for PhenforminN/ATypical Dosage for PhenforminOral: 25 to 50mg 1 to 4 times daily; maximum up to 100mg/daySchedule of PhenforminGStorage Requirements for PhenforminStore at room temperature at a range of 15 to 30 degree C.in a well closed container.
Keep out of reach of children.
Effects of Missed Dosage of PhenforminTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of PhenforminProvide supportive measures and symptomatic treatment.
Home Delivery for Phenformin in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including phenformin.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for phenformin and other medicines and health products. Home delivery services for phenformin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take phenformin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for phenformin before they complete the sale. You can get this information while placing the order for phenformin with the pharmacy.
Phenformin is a generic medicine name and there are several brands available for it. Some of the brands for phenformin might be better known than phenformin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have phenformin in stock, you can ask for one of the branded alternatives for phenformin.