Lomefloxacin (Eye Prep.) Pharmacology

Lomefloxacin (Eye Prep.)

About Lomefloxacin (Eye Prep.)
A synthetic second generation fluoroquinolone antibiotic, Antibiotic.
Mechanism of Action of Lomefloxacin (Eye Prep.)
Lomefloxacin is a diflourinated quinolone. Lomefloxacin is a bactericidal drug. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Lomefloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis:
Pharmacokinets of Lomefloxacin (Eye Prep.)
Absorption: Absorption after ophthalmic application is minimal
Onset of Action for Lomefloxacin (Eye Prep.)
N/A
Duration of Action for Lomefloxacin (Eye Prep.)
N/A
Half Life of Lomefloxacin (Eye Prep.)
N/A
Side Effects of Lomefloxacin (Eye Prep.)
1.Burning
2.Irritation
3.Itching
4.Pain
5.Photosensitisation
6.Allergic reactions
Contra-indications of Lomefloxacin (Eye Prep.)
1.Hypersensitivity to Lomefloxacin and other Fluoroquinolones
Special Precautions while taking Lomefloxacin (Eye Prep.)
1.Prolonged use
2.If irritation occurs then discontinue the use of medicaments
3.Avoid contact lenses
4. Wear sun glasses if sensitivity to sunlight occurs
Pregnancy Related Information
Used with caution
Old Age Related Information
Used with caution
Breast Feeding Related Information
Used with caution
Children Related Information
Contraindicated
NEONATES: Contraindicated
Indications for Lomefloxacin (Eye Prep.)
1.Bacterial Conjunctivitis
2.Corneal ulcers
3.Keratitis
4.Blepharitis
5.Keratoconjunctivitis
Interactions for Lomefloxacin (Eye Prep.)
N/A
Typical Dosage for Lomefloxacin (Eye Prep.)
Lomefloxacin 0.3 %w/v drops is available.
Eye drops:
Initial dose: 5 drops instill into the conjunctival sac within 20 minutes. Then, instill 1 drop 3 times daily into the conjunctival sac for 7 - 9 days.
Schedule of Lomefloxacin (Eye Prep.)
N/A
Storage Requirements for Lomefloxacin (Eye Prep.)
Store at cool dry place. Protect from light. Do not freeze. Keep out of the reach of children. Avoid use of medicament 1 month after opening.
Effects of Missed Dosage of Lomefloxacin (Eye Prep.)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Lomefloxacin (Eye Prep.)
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes.

Home Delivery for Lomefloxacin (Eye Prep.) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including lomefloxacin (eye prep.).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for lomefloxacin (eye prep.) and other medicines and health products. Home delivery services for lomefloxacin (eye prep.) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take lomefloxacin (eye prep.) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for lomefloxacin (eye prep.) before they complete the sale. You can get this information while placing the order for lomefloxacin (eye prep.) with the pharmacy.

Lomefloxacin (Eye Prep.) is a generic medicine name and there are several brands available for it. Some of the brands for lomefloxacin (eye prep.) might be better known than lomefloxacin (eye prep.) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have lomefloxacin (eye prep.) in stock, you can ask for one of the branded alternatives for lomefloxacin (eye prep.).