Sparfloxacin (Eye Prep.) Pharmacology

Sparfloxacin (Eye Prep.)

About Sparfloxacin (Eye Prep.)
A third generation fluoroquinolone, Ophthalmic antibiotic.
Mechanism of Action of Sparfloxacin (Eye Prep.)
Sparfloxacin is a bacteriostatic at low concentration and bactericidal at high concentration. It acts by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Sparfloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.
Pharmacokinets of Sparfloxacin (Eye Prep.)
Absorption: Absorption after ophthalmic application is minimal.

Onset of Action for Sparfloxacin (Eye Prep.)
N/A
Duration of Action for Sparfloxacin (Eye Prep.)
N/A
Half Life of Sparfloxacin (Eye Prep.)
15 - 20 hour
Side Effects of Sparfloxacin (Eye Prep.)
1. Burning
2. Irritation
3. Itching
4. Bitter taste
5. Blurred vision
6. Increased sensitivity of the eyes to light
7. Redness
8. Swelling
9. Pain
Contra-indications of Sparfloxacin (Eye Prep.)
1. Hypersensitivity to Sparfloxacin and other Fluoroquinolones
2. Not use injection or subconjunctivally in to the eye
Special Precautions while taking Sparfloxacin (Eye Prep.)
1. Prolonged use
2. If irritation occurs then discontinue the use of medicaments
3. Avoid contact lenses
4. Wear sun glasses if sensitivity to sunlight occurs
5. Avoid driving vehicle since it causes blurred vision
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Contraindicated
NEONATES: Contraindicated
Indications for Sparfloxacin (Eye Prep.)
1. Bacterial Conjunctivitis
2. Corneal ulcers
3. Keratitis
4. Blepharitis
5. Dacrocystitis
6. Trachoma
7. Keratoconjunctivitis
8. Acute meibomianitis
9. Prophylaxis of ocular infections
10. Treatment of superficial ocular infections.
Interactions for Sparfloxacin (Eye Prep.)
N/A
Typical Dosage for Sparfloxacin (Eye Prep.)
Sparfloxacin 0.3 %w/v drops is available.
Eye drops: Instill 1-2 drops in the affected eye. The frequency can be adjusted based on the severity of infection.
Schedule of Sparfloxacin (Eye Prep.)
N/A
Storage Requirements for Sparfloxacin (Eye Prep.)
Store at cool dry place. Protect from light. Do not freeze. Keep out of the reach of children. Avoid use of medicament 1 month after opening.
Effects of Missed Dosage of Sparfloxacin (Eye Prep.)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Sparfloxacin (Eye Prep.)
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of warm water for at least 15 minutes.

Home Delivery for Sparfloxacin (Eye Prep.) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including sparfloxacin (eye prep.).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sparfloxacin (eye prep.) and other medicines and health products. Home delivery services for sparfloxacin (eye prep.) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take sparfloxacin (eye prep.) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sparfloxacin (eye prep.) before they complete the sale. You can get this information while placing the order for sparfloxacin (eye prep.) with the pharmacy.

Sparfloxacin (Eye Prep.) is a generic medicine name and there are several brands available for it. Some of the brands for sparfloxacin (eye prep.) might be better known than sparfloxacin (eye prep.) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sparfloxacin (eye prep.) in stock, you can ask for one of the branded alternatives for sparfloxacin (eye prep.).