Polymyxin B (Eye Prep.) Pharmacology

Polymyxin B (Eye Prep.)

About Polymyxin B (Eye Prep.)
Basic polypeptide(Polymyxin)antibiotic, Ophthalmic Antibiotic.
Mechanism of Action of Polymyxin B (Eye Prep.)
Polymixin B is a member of poly peptide antibiotic. Being poly peptide they exert a detergent like effect. They have high affinity for phospholipids. Peptide molecules orient between these phospholipids and cause cell membrane distortion and amino acids and ions come out with in the cell. Polymixin B binds to the lipid A portion of endotoxin (lipopolysaccharide portion of the outer membrane of gram negative bacteria) and inactivates this molecule. Polymixin B is useful only against gram negative bacteria.
Pharmacokinets of Polymyxin B (Eye Prep.)
Absorption: Absorption of the drug after ophthalmic use is minimal.
Onset of Action for Polymyxin B (Eye Prep.)
N/A
Duration of Action for Polymyxin B (Eye Prep.)
N/A
Half Life of Polymyxin B (Eye Prep.)
N/A
Side Effects of Polymyxin B (Eye Prep.)
1.Burning
2.Stinging
3.Irritation
4.Itching
5.Redness
6.Blurred vision
7.Eyelid swelling
8.Tearing
9.Sensitivity to light.
Contra-indications of Polymyxin B (Eye Prep.)
Hypersensitivity to Polymixin B
Special Precautions while taking Polymyxin B (Eye Prep.)
1. Prolonged use
2. If irritation occurs then discontinue the use of medicaments
3. Avoid contact lenses
4. Wear sun glasses if sensitivity to sunlight occurs
5. Avoid driving vehicle since it causes blurred vision
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Contraindicated
Indications for Polymyxin B (Eye Prep.)
1.Conjunctivitis
2.Corneal ulcers
3.Keratitis
4.Blepnaritis
5.Pre and post ocular surgery
6.Prophylaxis of ocular bacterial infections

Interactions for Polymyxin B (Eye Prep.)
N/A
Typical Dosage for Polymyxin B (Eye Prep.)
Eye drops: Initial dose: Instill 1 - 2 drop every 2 - 6 hours for 2 - 3 days and then reduce the frequency of instillation.
Eye ointment: Apply 1.5cm ribbon every 3 hours in a day.
Schedule of Polymyxin B (Eye Prep.)
N/A
Storage Requirements for Polymyxin B (Eye Prep.)
Store at15 - 25 degree C in a dry place. Protect from light. Do not freeze. Keep out of the reach of children. Avoid use of medicament 1 month after opening.
Effects of Missed Dosage of Polymyxin B (Eye Prep.)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Polymyxin B (Eye Prep.)
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes.

Home Delivery for Polymyxin B (Eye Prep.) in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for polymyxin b (eye prep.) and other medicines and health products. Home delivery services for polymyxin b (eye prep.) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take polymyxin b (eye prep.) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for polymyxin b (eye prep.) before they complete the sale. You can get this information while placing the order for polymyxin b (eye prep.) with the pharmacy.

Polymyxin B (Eye Prep.) is a generic medicine name and there are several brands available for it. Some of the brands for polymyxin b (eye prep.) might be better known than polymyxin b (eye prep.) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have polymyxin b (eye prep.) in stock, you can ask for one of the branded alternatives for polymyxin b (eye prep.).