Idoxuridine Pharmacology

Idoxuridine

About Idoxuridine
A nucleoside (pyrimidine )analogue, Ophthalmic Antiviral.
Mechanism of Action of Idoxuridine
Idoxuridine is an iodinated Thymidine analog. It inhibits viral DNA synthesis and is incorporated in to both viral and cellular DNA. This will leads to formation of faulty DNA which breaks easily. Idoxuridine lacks selectivity and it inhibits the growth of uninfected cells also. It inhibits the replication of only DNA viruses like herpes viruses and pox viruses.
Pharmacokinets of Idoxuridine
Absorption: Absorption after ophthalmic use is limited.
Onset of Action for Idoxuridine
N/A
Duration of Action for Idoxuridine
N/A
Half Life of Idoxuridine
N/A
Side Effects of Idoxuridine
1.Stinging
2.Superficial punctuated Keratitis
3.Eye irritation
4.Pain
5.Redness
6. Inflammation of the lining of the eye and eyelids
Contra-indications of Idoxuridine
1. Hypersensitivity to Idoxuridine
Special Precautions while taking Idoxuridine
1. Stop the use of medicaments if allergic reactions occur
2. Avoid wearing of contact lenses
Pregnancy Related Information
Use with caution.
Old Age Related Information
May be used.
Breast Feeding Related Information
Use with caution.
Children Related Information
Use with caution
NEONATES: contraindicated
Indications for Idoxuridine
1. Viral infections- Herpes simplex Keratitis
Interactions for Idoxuridine
N/A
Typical Dosage for Idoxuridine
Idoxuridine 0.1% eye drop and eye ointment is used.
Instill 1drop in the affected eye every hour during the day and every 2 hour during night and if sufficient response is obtained then reduce the dose to 1 drop every two hours during the day and every four hours during the night.
Treatment should be continued for at least seven days.
Eye ointment: Apply every four hours during the day (five times a day).
Schedule of Idoxuridine
N/A
Storage Requirements for Idoxuridine
Store at room temperature. Protect from light and heat. Keep out of the reach of children. Avoid use of medicament 1 month after opening.
Effects of Missed Dosage of Idoxuridine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Idoxuridine
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes

Home Delivery for Idoxuridine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including idoxuridine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for idoxuridine and other medicines and health products. Home delivery services for idoxuridine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take idoxuridine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for idoxuridine before they complete the sale. You can get this information while placing the order for idoxuridine with the pharmacy.

Idoxuridine is a generic medicine name and there are several brands available for it. Some of the brands for idoxuridine might be better known than idoxuridine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have idoxuridine in stock, you can ask for one of the branded alternatives for idoxuridine.