Diclofenac (Eye Prep.) Pharmacology

Diclofenac (Eye Prep.)

About Diclofenac (Eye Prep.)
NSAID, Ophthalmic sterile, topical anti-inflammatory ,analgesic.
Mechanism of Action of Diclofenac (Eye Prep.)
Diclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (((PGs))). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake
Pharmacokinets of Diclofenac (Eye Prep.)
Absorption: Absorption is negligible after instillation in to the eye.
Onset of Action for Diclofenac (Eye Prep.)
Duration of Action for Diclofenac (Eye Prep.)
Half Life of Diclofenac (Eye Prep.)
Side Effects of Diclofenac (Eye Prep.)
4.Dry eyes
5.Bleeding in the eye
6.Blurred vision
7. Increased sensitivity of the eyes to light
Contra-indications of Diclofenac (Eye Prep.)
Hypersensitivity to Diclofenac
Special Precautions while taking Diclofenac (Eye Prep.)
1. Prolonged use
2. If irritation occurs then discontinue the use of medicaments
3. Avoid contact lenses
4. Wear sun glasses if sensitivity to sunlight occurs
5. Avoid driving vehicle, operating machine since it produces blurred vision
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Indications for Diclofenac (Eye Prep.)
1. Ocular surgery
2.Treatment of post operative ocular inflammation
3.Prevention of surgically induced miosis
4.Post-photorefractive keratectomy pain
5.Cataract Procedures
6.Inflammatory Conditions (((conjunctivitis, keratoconjunctivitis, and corneal ulcers)))
Interactions for Diclofenac (Eye Prep.)
Typical Dosage for Diclofenac (Eye Prep.)
Diclofenac sodium 0.1%w/v is used. 1-2 drops is instilled in to the eye every 6 - 8 hours a day.
Ocular surgery: Starts from 3 hours before surgery as 1 drop every hour followed by 1 drop 3 times daily after surgery.
Treatment of post operative ocular inflammation: 24 hours after surgery instill 1-2 drops for 4 times daily.
Prevention of surgically induced miosis: Instill 1 - 2 drops 4 times within 2 hours before surgery.
Post-photorefractive keratectomy pain: Instill 1 - 2 drop in to the eye 2 times within 1 hour before surgery followed by 1 drop twice at 5 minutes interval after surgery and 1 drop every 2 - 5 hours after1 day.
Cataract Procedures: Pre-operatively: instill 1 drop in the conjunctival sac up to 5 times within 3 hours before surgery. Post-operatively: instill 1 drop in the conjunctival sac 15, 30 and 45 minutes following surgery, then 3 to 5 times daily, for as long as required.
Inflammatory Conditions (((conjunctivitis, keratoconjunctivitis, and corneal ulcers))): instill 1 drop in the conjunctival sac 4 to 5 times daily, depending upon the severity of the disease.
Schedule of Diclofenac (Eye Prep.)
Storage Requirements for Diclofenac (Eye Prep.)
Store at cool dry place. Protect from heat and direct light. Do not freeze. Keep out of the reach of children. Avoid use of medicament 1 month after opening.
Effects of Missed Dosage of Diclofenac (Eye Prep.)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Diclofenac (Eye Prep.)
Give supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes.

Home Delivery for Diclofenac (Eye Prep.) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including diclofenac (eye prep.).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for diclofenac (eye prep.) and other medicines and health products. Home delivery services for diclofenac (eye prep.) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take diclofenac (eye prep.) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for diclofenac (eye prep.) before they complete the sale. You can get this information while placing the order for diclofenac (eye prep.) with the pharmacy.

Diclofenac (Eye Prep.) is a generic medicine name and there are several brands available for it. Some of the brands for diclofenac (eye prep.) might be better known than diclofenac (eye prep.) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have diclofenac (eye prep.) in stock, you can ask for one of the branded alternatives for diclofenac (eye prep.).