Dipivefrine Pharmacology

Dipivefrine

About Dipivefrine
Adrenergic Alpha/Beta agonist, prodrug of adrenaline, Ophthalmic Vasoconstrictor, Antiglaucoma ,miotic.
Mechanism of Action of Dipivefrine
Dipivefrine is an ester of Adrenaline and Pivalic acid. It is converted in the eye to active adrenaline. Adrenaline then acts on adrenoceptors in the walls of blood vessels in the eye and produces vasoconstriction and reduces blood flow. This will leads to decreased production of aqueous humor. Adrenaline is also increases the drainage of the fluid from the eye. It opens the drainage channels in the eye and allows fluid to leave the eye and relieves pressure. As adrenaline decreases the amount of fluid inside the eye, it is useful in treating glaucoma.
Pharmacokinets of Dipivefrine
Absorption: Dipivefrine is easily penetrated in to the anterior chamber of the eye.
Onset of Action for Dipivefrine
30 minutes
Duration of Action for Dipivefrine
12 hours
Half Life of Dipivefrine
N/A
Side Effects of Dipivefrine
1 Burning
2.Stinging
3.Conjunctivitis
4.Mydriasis
5.Photophobia
6.Conjunctival hyperemia
7.Arrhythmia
8.Hypertension
9.Tachycardia
Contra-indications of Dipivefrine
1.Hypersensitivity to Dipivefrine, Adrenaline
2.Angle closure glaucoma
Special Precautions while taking Dipivefrine
1.Asthma
2 Aphakia
3.Arrhythmia
4.Avoid use of soft contact lens for minimum of 15 minutes after instillation of drops
5.Do not operate machine or drive vehicle since it produce blurred vision
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Contraindicated
NEONATES: contraindicated
Indications for Dipivefrine
1.Open angle glaucoma
2.Ocular hypertension
Interactions for Dipivefrine
N/A
Typical Dosage for Dipivefrine
N/A
Schedule of Dipivefrine
N/A
Storage Requirements for Dipivefrine
Store in a cool dry place in a tightly closed container. Protect from heat and light. Keep out of the reach of children. Discard the drug 1 month after opening.
Effects of Missed Dosage of Dipivefrine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Dipivefrine
A topical ocular overdose of an ophthalmic product containing Dipivefrine may be flushed from the eye with warm tap water.

Home Delivery for Dipivefrine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including dipivefrine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dipivefrine and other medicines and health products. Home delivery services for dipivefrine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take dipivefrine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dipivefrine before they complete the sale. You can get this information while placing the order for dipivefrine with the pharmacy.

Dipivefrine is a generic medicine name and there are several brands available for it. Some of the brands for dipivefrine might be better known than dipivefrine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dipivefrine in stock, you can ask for one of the branded alternatives for dipivefrine.