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- Pharmacology For Dimethicone + Zinc oxide + Calamine + Cetrimide
Dimethicone + Zinc oxide + Calamine + Cetrimide Pharmacology
Dimethicone + Zinc oxide + Calamine + CetrimideAbout Dimethicone + Zinc oxide + Calamine + CetrimideN/AMechanism of Action of Dimethicone + Zinc oxide + Calamine + CetrimideN/APharmacokinets of Dimethicone + Zinc oxide + Calamine + CetrimideN/AOnset of Action for Dimethicone + Zinc oxide + Calamine + CetrimideN/ADuration of Action for Dimethicone + Zinc oxide + Calamine + CetrimideN/AHalf Life of Dimethicone + Zinc oxide + Calamine + CetrimideN/ASide Effects of Dimethicone + Zinc oxide + Calamine + CetrimideN/AContra-indications of Dimethicone + Zinc oxide + Calamine + CetrimideN/ASpecial Precautions while taking Dimethicone + Zinc oxide + Calamine + CetrimideN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Dimethicone + Zinc oxide + Calamine + CetrimideN/AInteractions for Dimethicone + Zinc oxide + Calamine + CetrimideN/ATypical Dosage for Dimethicone + Zinc oxide + Calamine + CetrimideN/ASchedule of Dimethicone + Zinc oxide + Calamine + CetrimideN/AStorage Requirements for Dimethicone + Zinc oxide + Calamine + CetrimideN/AEffects of Missed Dosage of Dimethicone + Zinc oxide + Calamine + CetrimideN/AEffects of Overdose of Dimethicone + Zinc oxide + Calamine + CetrimideN/A
DimethiconeAbout DimethiconeOral anti -foaming agent, a flexible silicone polymer, Antiflatulent ,Antibloating agent.Mechanism of Action of DimethiconeActivated Dimethicone relieves flatulence by dispensing and preventing formation of mucus surrounding gas pockets in the gastro-intestinal tract. It lowers the surface tension of the gas bubbles and bringing together all the small bubbles of gas (coalesce) to form a large bubble, which is then expelled. Thus the gas is freed by belching or passing flatus.
Antiflatulents are added to an antacid gum coating to be effective antigas materials and eliminate trapped gas. The most common antigas material is Dimethicone and when mixed with silicone dioxide becomes Simethicone. Simethicone is also referred to as activated Dimethicone. Simethicone is the most common antigas material and may be the only drug approved antiflatulent.
As the antacid chewing tablet is chewed, the active antacid and antiflatulent in the gum coating is released into the saliva and ingested to give relief from gastrointestinal disturbances in the gastro-intestinal tract.
Besides its antigas effect, Simethicone used in a gum coating can also improve the smoothness of the coating. Activated Dimethicone helps to relieve pain and bloating caused by trapped wind.
Pharmacokinets of DimethiconeN/AOnset of Action for DimethiconeN/ADuration of Action for DimethiconeN/AHalf Life of DimethiconeN/ASide Effects of DimethiconeN/AContra-indications of DimethiconeHypersensitivity to Dimethicone activatedSpecial Precautions while taking DimethiconeKidney failurePregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Dimethicone1. Flatulent dyspepsia
2. Postoperative distension
3. Gastric Distention
4. Functional digestive disorders
5. Stomach pain
7. Nausea and excess gas (dyspepsia)
Interactions for DimethiconeN/ATypical Dosage for Dimethicone125 - 166 mg taken half an hour before food.
Dimethicone in a coated chewing gum: 5 mg - 200 mg per piece of coated gum.
With an antacid: 20 mg -50 mg of Dimethicone
Schedule of DimethiconeN/AStorage Requirements for DimethiconeStored at room temperature (15-30?C) away from moisture and heat.Effects of Missed Dosage of DimethiconeTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of DimethiconeGive symptomatic and supportive treatment.
Zinc oxideAbout Zinc oxideZinc compound, A sunscreen,antipruritic.Mechanism of Action of Zinc oxideIt works by providing a skin barrier and helps in healing and prevent skin irritation. It acts as a sunscreen which absorbs incident solar radiation in the UVA ranges and reduces its transmission to the skin.Pharmacokinets of Zinc oxideN/AOnset of Action for Zinc oxideN/ADuration of Action for Zinc oxideN/AHalf Life of Zinc oxideN/ASide Effects of Zinc oxide1.Rash
4.Tightness in the chest
5.Swelling of the mouth, face, lips, or tongue
6.Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
7.Stop using zinc oxide rectal suppositories if you have rectal bleeding or continued pain.
Contra-indications of Zinc oxide1.Hypersensitivity to Zinc oxide
2.Allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax. Special Precautions while taking Zinc oxide1.Allergic to Zinc preparations
2.Zinc oxide topical will not treat a bacterial or fungal infection
3.Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper
4.Avoid getting this medication in your mouth or eyes
5.Do not use zinc oxide topical on deep skin wounds or severe burns
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Zinc oxide1.To prevent minor skin irritations such as burns, cuts, poison ivy, poison oak, poison sumac, and diaper rash.
3.Zinc oxide topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations.
4.Zinc oxide rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements
Interactions for Zinc oxideN/ATypical Dosage for Zinc oxideApply the medicament to the affected part 2 times daily.Schedule of Zinc oxideN/AStorage Requirements for Zinc oxideStore at 15 - 30 degree C.Protect from heat,light and moisture.Keep out of the reach of children.Effects of Missed Dosage of Zinc oxideApply the missed dose as soon as noticed.Effects of Overdose of Zinc oxideGive supportive measures and symptomatic treatment.
CalamineAbout CalamineAntipruritic, mild antiseptic, astringent.Mechanism of Action of CalamineCalamine is an anti-pruritics, which are used to relieve itching. Itching can be caused by physical irritation or chemical changes in the skin caused by disease, allergy, inflammation, side-effects of drugs, or reaction to irritant substances. It is a common symptom of skin disorders, e.g. eczema, and infection with lice or worms. Calamine is used as it has a cooling and soothing effect on the skin for symptomatic relief of the itching. It also contains the active ingredient zinc oxide, which has antiseptic properties and helps prevent infection from scratching.Pharmacokinets of CalamineN/AOnset of Action for CalamineN/ADuration of Action for CalamineN/AHalf Life of CalamineN/ASide Effects of Calamine1.Hives
3.Swelling of face, lips, tongue, or throat.
Contra-indications of Calamine1.Hypersensitivity to Calamine
2. Oozing skinSpecial Precautions while taking Calamine1.Do not use on extensive areas of skin for longer than 7 days
2.Avoid contact with mucous membranes and eyes
3.Discontinue if rash or burning sensation occurs
4.Avoid contact with eyes or mouth or nose.
Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be usedIndications for Calamine1.To relieve the itching, pain, and discomfort of minor skin irritationsInteractions for CalamineN/ATypical Dosage for CalamineApply calamine directly to the skin and rub in gently, allowing to dry on your skin. Apply 3 to 4 times a day.Schedule of CalamineN/AStorage Requirements for CalamineStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.Keep out of the reach of children.
Effects of Missed Dosage of CalamineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Do not double the dose.Continue the regular schedule.Effects of Overdose of CalamineGive supportive measures and sympptomatic treatment.
CetrimideAbout CetrimideQuaternary ammonium compound, a cationic surfactant, Antiseptic agent, a detergent ,disinfectant.Mechanism of Action of CetrimideCetrimide is a cationic surfactant. It destroys or damages the cell membrane by lowering surface tension. It causes microbial protein denaturation and produces antiseptic action.Pharmacokinets of CetrimideAbsorption: Cetrimide is poorly absorbed after topical administration through intact skin.Onset of Action for CetrimideN/ADuration of Action for CetrimideN/AHalf Life of CetrimideN/ASide Effects of Cetrimide1.Skin irritation
2.Redness of the skin
Contra-indications of Cetrimide1.Hypersensitivity to CetrimideSpecial Precautions while taking Cetrimide1.For external use only
2.Avoid contact with eyes, middle ear, meninges, brain
3.Avoid use in body cavities
4.Wash thoroughly with water
Pregnancy Related InformationMay be used.Old Age Related InformationMay be used.Breast Feeding Related InformationMay be usedChildren Related InformationMay be used.Indications for CetrimideAntiseptic and disinfectant
7.Preoperative applications to hands
8.Disinfectant hospital vessels
Interactions for CetrimideIncompatible with soaps and other anionic surfactants, iodine alkali hydroxides.Typical Dosage for CetrimideAdult: Apply 2 - 3 times daily
As Disinfectant: Cetrimide 15% and Cetrimide 20 % are used
As antiseptic: Cetrimide 3% and: Cetrimide 7.5 % are used.
Schedule of CetrimideN/AStorage Requirements for CetrimideStore in a cool, dry and dark place.Effects of Missed Dosage of CetrimideApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CetrimideGive supportive measures and symptomatic treatment
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