Fusidic acid + Betamethasone valerate Pharmacology

Fusidic acid + Betamethasone valerate

About Fusidic acid + Betamethasone valerate
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Mechanism of Action of Fusidic acid + Betamethasone valerate
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Pharmacokinets of Fusidic acid + Betamethasone valerate
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Onset of Action for Fusidic acid + Betamethasone valerate
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Duration of Action for Fusidic acid + Betamethasone valerate
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Half Life of Fusidic acid + Betamethasone valerate
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Side Effects of Fusidic acid + Betamethasone valerate
N/A
Contra-indications of Fusidic acid + Betamethasone valerate
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Special Precautions while taking Fusidic acid + Betamethasone valerate
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Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Fusidic acid + Betamethasone valerate
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Interactions for Fusidic acid + Betamethasone valerate
N/A
Typical Dosage for Fusidic acid + Betamethasone valerate
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Schedule of Fusidic acid + Betamethasone valerate
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Storage Requirements for Fusidic acid + Betamethasone valerate
N/A
Effects of Missed Dosage of Fusidic acid + Betamethasone valerate
N/A
Effects of Overdose of Fusidic acid + Betamethasone valerate
N/A

Fusidic acid

About Fusidic acid
A bacteriostatic Steroid Antibiotic, Systemic antibacterial, anti-infective.
Mechanism of Action of Fusidic acid
Fusidic acid is a bactericidal or bacteriostatic drug depending upon the concentration. It inhibits the transfer of aminoacid from aminoacyl sRNA to the protein. This will leads to inhibition of protein synthesis in the bacteria and prevent the growth of microbes.
Pharmacokinets of Fusidic acid
Absorption: It is very poorly absorbed after topical administration.
Onset of Action for Fusidic acid
NULL.
Duration of Action for Fusidic acid
NULL.
Half Life of Fusidic acid
N/A
Side Effects of Fusidic acid
1. Contact dermatitis
2. Irritation
3. Burning
4. Redness
5. Swelling
6. Rashes
Contra-indications of Fusidic acid
1. Hypersensitivity to Fusidic acid
Special Precautions while taking Fusidic acid
1. Avoid contact with eyes
2. If irritation occurs discard the use of medicament
3. Hepatic impairment
4. Monitor liver function test
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Fusidic acid
Primary and secondary skin infections
1. Impetigo
2. Erythrasma
3. Folliculitis
4. Sycosis barbae
5. Hidradenitis
Interactions for Fusidic acid
NULL.
Typical Dosage for Fusidic acid
Fusidic acid 2% cream or ointment .Clean and dry the affected area. Apply the drug as thin layer.2 - 4 times daily.
Schedule of Fusidic acid
N/A
Storage Requirements for Fusidic acid
Store in a cool dry place. Protect from heat and light. Keep out of the reach of children
Effects of Missed Dosage of Fusidic acid
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Fusidic acid
Give supportive measures and symptomatic treatment.

Betamethasone valerate

About Betamethasone valerate
It is a topical steroid
Mechanism of Action of Betamethasone valerate
The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-alpha, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemotaxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of Betamethasone valerate
Absorption: It is absorbed in to the systemic circulation and the amount is depending on the potency, amount applied and the nature of the skin at the site of application. Absorption increases at the site of skin damage, inflammation or occlusion.

Onset of Action for Betamethasone valerate
N/A
Duration of Action for Betamethasone valerate
N/A
Half Life of Betamethasone valerate
N/A
Side Effects of Betamethasone valerate
1.Thinning of the skin
2.Loss of elasticity
3.Increased hair growth
4.Acne at the site of application
5.Mild depigmentation
6.Rosacea
Contra-indications of Betamethasone valerate
1.Untreated bacterial, virus or fungal infections
2.Acne vulgaris,
3.Peri-oral dermatitis,
4.Scabies,
5.Leg ulcers,
6.Tuberculosis of the skin,
7.Varicose ulcers,
8.Skin lesions caused by infections with ring worm,. fungi (e.g. Candida, Tinea) or bacteria (e.g. impetigo)
9.Hypersensitivity to Betamethasone and other corticosteroids.
10.Discoid lupus Erythematosus
Special Precautions while taking Betamethasone valerate
1.Avoid contact with eyes
2.For external use only
3.Prolonged use
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: contraindicated
Indications for Betamethasone valerate
1.Psoriasis,
2.Eczema,
3.Otitis externa,
4.Lichen simplex and planus,
5.Anal and vulval Pruritis,
6.Seborrheic dermatitis,
7.Contact dermatitis,
8.Steroidal responsive dermatoses of the scalp
Interactions for Betamethasone valerate
N/A
Typical Dosage for Betamethasone valerate
Topical:
Betamethasone Valerate: Apply to the affected area as thin film 1 - 4 times daily depending upon the severity, skin and rate of absorption.
Dermatoses of the scalp: (Betamethasone Valerate 0.12%): Small amount of foam is applied in to the scalp with gentle massage 2 times a day for up to 2 weeks.
Schedule of Betamethasone valerate
N/A
Storage Requirements for Betamethasone valerate
Store at room temperature in a well closed; light resistant container. Protect from excess heat and moisture. Keep out of reach of children.
Effects of Missed Dosage of Betamethasone valerate
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Betamethasone valerate
Provide symptomatic treatment and supportive measures.

Home Delivery for Fusidic acid + Betamethasone valerate in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for fusidic acid + betamethasone valerate and other medicines and health products. Home delivery services for fusidic acid + betamethasone valerate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

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Fusidic acid + Betamethasone valerate is a generic medicine name and there are several brands available for it. Some of the brands for fusidic acid + betamethasone valerate might be better known than fusidic acid + betamethasone valerate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have fusidic acid + betamethasone valerate in stock, you can ask for one of the branded alternatives for fusidic acid + betamethasone valerate.