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- Pharmacology For Fusidic acid + Beclomethasone valerate
Fusidic acid + Beclomethasone valerate Pharmacology
Fusidic acid + Beclomethasone valerate
About Fusidic acid + Beclomethasone valerateN/AMechanism of Action of Fusidic acid + Beclomethasone valerateN/APharmacokinets of Fusidic acid + Beclomethasone valerateN/AOnset of Action for Fusidic acid + Beclomethasone valerateN/ADuration of Action for Fusidic acid + Beclomethasone valerateN/AHalf Life of Fusidic acid + Beclomethasone valerateN/ASide Effects of Fusidic acid + Beclomethasone valerateN/AContra-indications of Fusidic acid + Beclomethasone valerateN/ASpecial Precautions while taking Fusidic acid + Beclomethasone valerateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Fusidic acid + Beclomethasone valerateN/AInteractions for Fusidic acid + Beclomethasone valerateN/ATypical Dosage for Fusidic acid + Beclomethasone valerateN/ASchedule of Fusidic acid + Beclomethasone valerateN/AStorage Requirements for Fusidic acid + Beclomethasone valerateN/AEffects of Missed Dosage of Fusidic acid + Beclomethasone valerateN/AEffects of Overdose of Fusidic acid + Beclomethasone valerateN/AFusidic acid
About Fusidic acidA bacteriostatic Steroid Antibiotic, Systemic antibacterial, anti-infective.Mechanism of Action of Fusidic acidFusidic acid is a bactericidal or bacteriostatic drug depending upon the concentration. It inhibits the transfer of aminoacid from aminoacyl sRNA to the protein. This will leads to inhibition of protein synthesis in the bacteria and prevent the growth of microbes.Pharmacokinets of Fusidic acidAbsorption: It is very poorly absorbed after topical administration.Onset of Action for Fusidic acidNULL.Duration of Action for Fusidic acidNULL.Half Life of Fusidic acidN/ASide Effects of Fusidic acid1. Contact dermatitis
2. Irritation
3. Burning
4. Redness
5. Swelling
6. Rashes
Contra-indications of Fusidic acid1. Hypersensitivity to Fusidic acidSpecial Precautions while taking Fusidic acid1. Avoid contact with eyes
2. If irritation occurs discard the use of medicament
3. Hepatic impairment
4. Monitor liver function test
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Fusidic acidPrimary and secondary skin infections
1. Impetigo
2. Erythrasma
3. Folliculitis
4. Sycosis barbae
5. Hidradenitis
Interactions for Fusidic acidNULL.Typical Dosage for Fusidic acidFusidic acid 2% cream or ointment .Clean and dry the affected area. Apply the drug as thin layer.2 - 4 times daily. Schedule of Fusidic acidN/AStorage Requirements for Fusidic acidStore in a cool dry place. Protect from heat and light. Keep out of the reach of childrenEffects of Missed Dosage of Fusidic acidApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Fusidic acidGive supportive measures and symptomatic treatment.Beclomethasone valerate
About Beclomethasone valerateGlucocorticoid, anti-inflammatory, antipruritic and vasoconstrictive actions.Mechanism of Action of Beclomethasone valerateMechanism of action: The drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits Phospholipase A2 and thus decreases the production of Prostaglandins, leukotrienes (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-alpha, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemo taxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of Beclomethasone valerateAbsorption: It enters in to the systemic circulation after topical administration.Onset of Action for Beclomethasone valerateN/ADuration of Action for Beclomethasone valerateN/AHalf Life of Beclomethasone valerateN/ASide Effects of Beclomethasone valerate1.Thinning of the skin
2.Loss of elasticity
3.Increased hair growth
4.Acne at the site of application
5.Mild depigmentation
6.Rosacea
Contra-indications of Beclomethasone valerate1.Hypersensitivity to Beclomethasone
2.Untreated bacterial virus or fungal infections
3.Acne vulgaris
4.Peri-oral dermatitis
5.Tuberculosis of the skin
6.Varicose ulcers
7.Skin lesions caused by infections with herpes simplex vaccinia or varicella viruses. fungi (e.g. Candida Tinea) or bacteria (e.g. impetigo)
8.Discoid lupus Erythematosus
Special Precautions while taking Beclomethasone valerate1.Avoid contact with eyes
2.For external use only
3.Prolonged use
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: contraindicatedIndications for Beclomethasone valerate1.Eczema
2.Psoriasis
3.Contact dermatitis
4.Anal and vulval Pruritis
5.Inflammation of the skin
Interactions for Beclomethasone valerateN/ATypical Dosage for Beclomethasone valerateTopical: Apply as thin film 1 - 2 times daily on to the affected areaSchedule of Beclomethasone valerateN/AStorage Requirements for Beclomethasone valerateStore below 25 degree C in a tightly closed container. Keep out of the reach of childrenEffects of Missed Dosage of Beclomethasone valerateApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Beclomethasone valerateGive supportive measures and symptomatic treatment.Home Delivery for Fusidic acid + Beclomethasone valerate in Your City
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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for fusidic acid + beclomethasone valerate and other medicines and health products. Home delivery services for fusidic acid + beclomethasone valerate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take fusidic acid + beclomethasone valerate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for fusidic acid + beclomethasone valerate before they complete the sale. You can get this information while placing the order for fusidic acid + beclomethasone valerate with the pharmacy.
Fusidic acid + Beclomethasone valerate is a generic medicine name and there are several brands available for it. Some of the brands for fusidic acid + beclomethasone valerate might be better known than fusidic acid + beclomethasone valerate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have fusidic acid + beclomethasone valerate in stock, you can ask for one of the branded alternatives for fusidic acid + beclomethasone valerate.
