Sulindac Pharmacology

Sulindac

About Sulindac

NSAID, arylalkanoic acid derivative, Analgesic ,antiinflammatory.

Mechanism of Action of Sulindac

Sulindac produces its analgesics and anti-inflammatory actions by inhibiting Prostaglandin synthesis.

Pharmacokinets of Sulindac

Absorption: It is rapidly and completely absorbed after oral administration. Distribution: It is distributed mainly in protein bound form. Metabolism: It undergoes metabolism in the liver and produces active sulfide metabolite. Excretion: Drug and its metabolites are excreted mainly in urine.

Onset of Action for Sulindac

N/A

Duration of Action for Sulindac

N/A

Half Life of Sulindac

8 - 16 hours

Side Effects of Sulindac

1.Gastrointestinal pain
2.Dyspepsia
3.Nausea
4.Vomiting
5.Diarrhoea
6.Constipation
7.Flatulence
8.Anorexia
9.Gastrointestinal cramps.
10.Rash
11.Pruritus
12.Dizziness
13.Headache
14.Nervousness.
15.Tinnitus.
16.Edema

Contra-indications of Sulindac

1.Hypersensitivity to Sulindac

Special Precautions while taking Sulindac

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Sulindac

1.Osteoarthritis
2.Rheumatoid arthritis
3.Ankylosing spondylitis
4.Acute painful shoulder
5.Acute gouty arthritis

Interactions for Sulindac

N/A

Typical Dosage for Sulindac

300mg/day in 2divided doses; dose can be increased to 400mg/day if needed.
Acute painful shoulder, acute gouty arthritis: 400mg/day in 2 divided doses for 1 - 2 weeks.

Schedule of Sulindac

N/A

Storage Requirements for Sulindac

Store it at 15 -25 degree C in a tightly closed container .Protect away from heat and light. Keep out of the reach of children.

Effects of Missed Dosage of Sulindac

Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose and do not double the dose

Effects of Overdose of Sulindac

Give supportive measures and symptomatic treatment.Drug can be removed by inducing emesis or by gastric lavage.Absorption of the drug can be reduced by administration of activated charcoal.

Home Delivery for Sulindac in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including sulindac.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sulindac and other medicines and health products. Home delivery services for sulindac may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take sulindac only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sulindac before they complete the sale. You can get this information while placing the order for sulindac with the pharmacy.

Sulindac is a generic medicine name and there are several brands available for it. Some of the brands for sulindac might be better known than sulindac itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sulindac in stock, you can ask for one of the branded alternatives for sulindac.