Polio Vaccine - Oral Pharmacology

Polio Vaccine - Oral

About Polio Vaccine - Oral
Active Immunization Agent, Live attenuated (weakened)Viral vaccine, Protection against Poliomyelitis.
Mechanism of Action of Polio Vaccine - Oral
Oral Polio Vaccine (OPV) is made with live polio virus that has been weakened. OPV produces antibodies in the blood (`humeral` or serum immunity) to all three types of poliovirus. In the event of infection, this will protect the individual against polio paralysis by preventing the spread of poliovirus to the nervous system. OPV also produces a local immune response in the lining (mucous membrane) of the intestines - the primary site for poliovirus multiplication. Resulting antibodies limit the multiplication of wild (naturally occurring) virus inside the gut, preventing effective infection.
Pharmacokinets of Polio Vaccine - Oral
Antibody stimulation after oral administration occurs within 7-10 days and peaks at approximately 3 weeks. Drug is distributed into breast milk.
Onset of Action for Polio Vaccine - Oral
Duration of Action for Polio Vaccine - Oral
5 yrs after administration
Half Life of Polio Vaccine - Oral
Side Effects of Polio Vaccine - Oral
Contra-indications of Polio Vaccine - Oral
1.Allergies (especially drug allergies)
2.Immune system disorders
4.Certain blood disorders
Special Precautions while taking Polio Vaccine - Oral
The poliovirus vaccine should be used with caution in patients with a history of neomycin hypersensitivity or streptomycin hypersensitivity because these agents may be used in the preparation of OPV.
Pregnancy Related Information
Old Age Related Information
Breast Feeding Related Information
Children Related Information
Indications for Polio Vaccine - Oral
1. Protection from polio virus
Interactions for Polio Vaccine - Oral
Typical Dosage for Polio Vaccine - Oral
Adults :
0.5 ml PO initially, then repeated 8 weeks later. The third dose should be given 8-12 months after the second dose. When less than 4 weeks is available before immunization is required, a single 0.5 ml PO dose should be given.
Infants :
The first 0.5 ml PO dose should be administered at 6-12 weeks of age. The second 0.5 ml PO dose should be administered preferably 8 weeks after the first dose. The third 0.5 ml PO dose should be administered at 6 months of age, however, if this time cannot be met, the third dose may be administered as late as 18 months of age.
Children up to age 18 years :
0.5 mL PO initially, followed by the second dose preferably 8 weeks after the first dose. The third dose is given 8-12 months after the second dose (adolescents and older children may receive the third dose 6-8 weeks after the second dose if there is an increased risk of poliomyelitis). Booster doses are suggested upon starting school at 4-6 years of age, unless the third dose of the primary series was given after the recipient`s fourth birthday.
Schedule of Polio Vaccine - Oral
Storage Requirements for Polio Vaccine - Oral
Store at cold dark place.
Effects of Missed Dosage of Polio Vaccine - Oral
Effects of Overdose of Polio Vaccine - Oral

Home Delivery for Polio Vaccine - Oral in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for polio vaccine - oral and other medicines and health products. Home delivery services for polio vaccine - oral may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take polio vaccine - oral only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for polio vaccine - oral before they complete the sale. You can get this information while placing the order for polio vaccine - oral with the pharmacy.

Polio Vaccine - Oral is a generic medicine name and there are several brands available for it. Some of the brands for polio vaccine - oral might be better known than polio vaccine - oral itself. If the pharmacy that's willing to deliver medicines to your home doesn't have polio vaccine - oral in stock, you can ask for one of the branded alternatives for polio vaccine - oral.