Meloxicam Pharmacology


About Meloxicam
NSAID, Thiazole derivative, Oxicam class, Analgesic,anti-inflammatory.
Mechanism of Action of Meloxicam
This drug reduces the prostaglandin synthesis peripherally by inhibiting COX1 & COX2 isoenzymes. This results its antinflammatory action. It is a preferential COX2 inhibitor. It also inhibits TXA2 production.
Pharmacokinets of Meloxicam
Absorption- Well absorbed after administration.
Distribution- Drug is distributed widely in the plasma-protein bound form.99.4% bound to the plasma proteins.
Metabolism- Metabolized in the liver to its metabolites. The major metabolite 5`-carboxy meloxicam.
Excretion- Excreted through urine and faeces.
Onset of Action for Meloxicam
5 to 6 hrs.
Duration of Action for Meloxicam
20 hrs.
Half Life of Meloxicam
Side Effects of Meloxicam
1. Diarrhea
2. Constipation
3. Sore throat
4. Cough
5. Runny nose
6. Fever
7. Blisters
8. Hives
9. Itching
10. Swelling of the eyes, face, tongue, lips, throat, arms, hands, feet, ankles, or lower legs
11. Difficulty breathing or swallowing
12. Hoarseness
13. Pale skin
14. Fast heartbeat
15. Weight gain
16. Upset stomach
17. Tiredness
18. Pain in the right upper part of the stomach
19. Flu-like symptoms
20. Cloudy, discolored, or bloody urine
21. Back pain
22. Difficult or painful urination
Contra-indications of Meloxicam
1. Hypersensitivity to the drug
2. Hyper sensitivity to aspirin and other NSAID
3. Active peptic ulcer
4. Renal failure
5. Hepatic failure
6. Bleeding disorder
Special Precautions while taking Meloxicam
1. Alcohol abuse
2. Bleeding problems
3. Stomach ulcer
4. Tobacco abuse
5. Anemia
6. Asthma
7. Dehydration
8. Fluid retention (swelling of feet or lower legs)
9. High blood pressure
10. Kidney disease
11. Liver disease
12. Coronary artery bypass graft (CABG) surgery
13. Heart disease
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Children Related Information
Use with caution
Indications for Meloxicam
1. Rheumatoid arthritis
2. Osteoarthritis
3. Ankylosing spondylitis
4. Acute gout
Interactions for Meloxicam
No known interactions.
Typical Dosage for Meloxicam
Adults (from 15 years) -
15mg or 7.5mg (in dialysis patients).
Schedule of Meloxicam
Storage Requirements for Meloxicam
Store it at room temperature and away from excess heat and moisture. Keep out of the reach of children.
Effects of Missed Dosage of Meloxicam
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Meloxicam
Give symptomatic and supportive treatment. Induce gastric emesis and administer activated charcoal to reduce further adsorption of drugs.

Home Delivery for Meloxicam in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including meloxicam.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for meloxicam and other medicines and health products. Home delivery services for meloxicam may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take meloxicam only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for meloxicam before they complete the sale. You can get this information while placing the order for meloxicam with the pharmacy.

Meloxicam is a generic medicine name and there are several brands available for it. Some of the brands for meloxicam might be better known than meloxicam itself. If the pharmacy that's willing to deliver medicines to your home doesn't have meloxicam in stock, you can ask for one of the branded alternatives for meloxicam.