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- Pharmacology For Clobetasol propionate + Salicylic acid
Clobetasol propionate + Salicylic acid Pharmacology
Clobetasol propionate + Salicylic acid
About Clobetasol propionate + Salicylic acidN/AMechanism of Action of Clobetasol propionate + Salicylic acidN/APharmacokinets of Clobetasol propionate + Salicylic acidN/AOnset of Action for Clobetasol propionate + Salicylic acidN/ADuration of Action for Clobetasol propionate + Salicylic acidN/AHalf Life of Clobetasol propionate + Salicylic acidN/ASide Effects of Clobetasol propionate + Salicylic acidN/AContra-indications of Clobetasol propionate + Salicylic acidN/ASpecial Precautions while taking Clobetasol propionate + Salicylic acidN/APregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Clobetasol propionate + Salicylic acidIt is a combination of corticosteroid Clobetasol propionate and keratolytic Salicylic acid.
1.Psoriasis
2.Dermatitis
3.Eczema
4.Seborrheic dermatitis of the scalp
Interactions for Clobetasol propionate + Salicylic acidN/ATypical Dosage for Clobetasol propionate + Salicylic acidTopical use:
Apply the cream as thin layer to the affected area twice daily. Treatment should not continue for 1more than 14 days.
Below 12 years: Contraindicated
Schedule of Clobetasol propionate + Salicylic acidN/AStorage Requirements for Clobetasol propionate + Salicylic acidN/AEffects of Missed Dosage of Clobetasol propionate + Salicylic acidN/AEffects of Overdose of Clobetasol propionate + Salicylic acidN/AClobetasol propionate
About Clobetasol propionateTopical adenocorticoid, Anti inflammatory.Mechanism of Action of Clobetasol propionateClobetasol is a topical corticosteroid. It induces peptide Lipocortins which inhibit the enzyme Phospholipase A2. Phospholipase A2 is essential for the conversion of membrane phospholipids to Arachidonic acid. From this Arachidonic acid inflammatory mediators like prostaglandins, kinins, histamine, liposomal enzymes and the complement system are produced. By inhibiting Phospholipase A2 inflammatory mediators are not released. It also inhibits the migration of macrophages and leukocytes to the inflamed area by its vasoconstrictive properties. Corticosteroids also inhibit capillary production, collagen deposition and keloid (scar) formation. Thus inhibiting inflammatory mediators and other actions Clobetasol are used for anti-inflammatory conditions.Pharmacokinets of Clobetasol propionateAbsorption: Clobetasol is absorbed through intact skin after topical administration and the amount absorbed is depending on the type of inflammation, vehicle used, amount of drug applied and the epidermal barrier (nature of skin)Onset of Action for Clobetasol propionateN/ADuration of Action for Clobetasol propionateN/AHalf Life of Clobetasol propionateN/ASide Effects of Clobetasol propionate1.Thinning of epidermis
2.Burning
3. Itching
4.Irritation
5.Atrophy (Dermal changes)
6.Telangiectasia
7.Striae
8.Hypopigmentation
9.Contact dermatitis
10.Perioral dermatitis
Contra-indications of Clobetasol propionate1.Hypersensitivity to Clobetasol and other corticosteroids
2.Acne vulgaris
3.Acne Rosacea
4.Nappy rash
5.Tuberculosis infection of the skin
6.Viral,fungal or bacterial primary infections
7.Ulcers
Special Precautions while taking Clobetasol propionate1.Avoid application on large surface area
2.Prolonged use
3.Psoriasis
4.Avoid contact with eyes,mouth and mucous membrane
5.Avoid occlusive dressing or plastic damage
6.Not used more than 5 days on the face or in the children
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
Below12 years: ContraindicatedIndications for Clobetasol propionate1.Skin disorders
2.Eczema
3.Psoriasis
4.Alopecia areata
5.Inflammation of corticosteroid dermatoses (secondary infected)
6.Chronic discoid lupus Erythematosus
Interactions for Clobetasol propionateN/ATypical Dosage for Clobetasol propionateTopical: Clobetasol 0.05 % cream and gel are available. Medicament is applied thinly and evenly on the affected area. 2 times a day, maximum 2 weeks. Maximum dose: 50 g of the cream/ week. Schedule of Clobetasol propionateHStorage Requirements for Clobetasol propionateStore at room temperature. Protect from heat, moisture and light. Keep out of the reach of childrenEffects of Missed Dosage of Clobetasol propionateApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Clobetasol propionateGive supportive measures and symptomatic treatment.Salicylic Acid
About Salicylic AcidA beta hydroxy acid, Keratolytic, Topical Skin Product(Anti Acne).Mechanism of Action of Salicylic AcidIt is a keratolytic agent. It encourages exfoliation of the skin and opening up of the plugged follicles, which helps re-establish the normal skin- cell replacement cycle. For milder acne, salicylic acid helps unclog pores to resolve and prevent lesions.Pharmacokinets of Salicylic AcidN/AOnset of Action for Salicylic AcidN/ADuration of Action for Salicylic AcidN/AHalf Life of Salicylic AcidN/ASide Effects of Salicylic Acid1.Allergic reaction
2.Hives
3.Difficulty breathing
4.Swelling of your face, lips, tongue, or throat.
Contra-indications of Salicylic Acid1.Hypersensitivity to Salicylic acidSpecial Precautions while taking Salicylic Acid1.Avoid contact with eyes, mouth, or nose.
2.Like many other topical acne treatments, salicylic acid must be used continuously, even after acne lesions have.Pregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Salicylic Acid1.Treats skin irritation and inflammation caused by burns, insect bites, fungal infections, and eczema.Interactions for Salicylic AcidN/ATypical Dosage for Salicylic AcidUse this medication twice daily Schedule of Salicylic AcidN/AStorage Requirements for Salicylic AcidStore in a cool dry place. Protect from heat and light. Keep out of the reach of childrenEffects of Missed Dosage of Salicylic AcidApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Salicylic AcidGive supportive measures and symptomatic treatment.Home Delivery for Clobetasol propionate + Salicylic acid in Your City
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Please be aware that you should take clobetasol propionate + salicylic acid only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for clobetasol propionate + salicylic acid before they complete the sale. You can get this information while placing the order for clobetasol propionate + salicylic acid with the pharmacy.
Clobetasol propionate + Salicylic acid is a generic medicine name and there are several brands available for it. Some of the brands for clobetasol propionate + salicylic acid might be better known than clobetasol propionate + salicylic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have clobetasol propionate + salicylic acid in stock, you can ask for one of the branded alternatives for clobetasol propionate + salicylic acid.
