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Irgason dp + Vitamin C Pharmacology
Irgason dp + Vitamin CAbout Irgason dp + Vitamin CN/AMechanism of Action of Irgason dp + Vitamin CN/APharmacokinets of Irgason dp + Vitamin CN/AOnset of Action for Irgason dp + Vitamin CN/ADuration of Action for Irgason dp + Vitamin CN/AHalf Life of Irgason dp + Vitamin CN/ASide Effects of Irgason dp + Vitamin CN/AContra-indications of Irgason dp + Vitamin CN/ASpecial Precautions while taking Irgason dp + Vitamin CN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Irgason dp + Vitamin CN/AInteractions for Irgason dp + Vitamin CN/ATypical Dosage for Irgason dp + Vitamin CN/ASchedule of Irgason dp + Vitamin CN/AStorage Requirements for Irgason dp + Vitamin CN/AEffects of Missed Dosage of Irgason dp + Vitamin CN/AEffects of Overdose of Irgason dp + Vitamin CN/A
Irgason dpAbout Irgason dpA diphenyl ether derivative, Antiseptic.Mechanism of Action of Irgason dpIrgason Dp is a chlorinated bisphenol antiseptic.It is useful against Gram-positive and most Gram-negative bacteria but with poor activity against Pseudomonas species. It is also active against fungi. It is used in soaps, creams, and solutions in concentrations of up to 2% for disinfection of the hands and wounds and for disinfection of the skin prior to surgery, injections, or venepuncture. It is also used in oral hygiene products and in preparations for acne.Pharmacokinets of Irgason dpN/AOnset of Action for Irgason dpN/ADuration of Action for Irgason dpN/AHalf Life of Irgason dpN/ASide Effects of Irgason dpN/AContra-indications of Irgason dpN/ASpecial Precautions while taking Irgason dp1.Avoid contact with eyesPregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Irgason dpAntisepticInteractions for Irgason dpN/ATypical Dosage for Irgason dpN/ASchedule of Irgason dpN/AStorage Requirements for Irgason dpN/AEffects of Missed Dosage of Irgason dpN/AEffects of Overdose of Irgason dpN/A
Vitamin CAbout Vitamin CWater soluble vitamin, antioxidant.Mechanism of Action of Vitamin CVitamin C exerts it`s action by influencing the biologic oxidations and reductions used in cellular respirations. It directly stimulates collagen synthesis and maintains intracellular connective tissue. It involves in various metabolic reactions such as 1).Hydroxylation of praline and lysine residues of protocollagen which is essential for formation and stabilization of collagen triple helix, 2).hydroxylation of carnitine, 3).Conversion of folic acid to folinic acid, 4).biosynthesis of adrenal steroids, catecholamines, oxytocin, and ADH, 5).Metabolism of cyclic nucleotides and prostaglandins. Vitamin C is important in resistance to infections.Pharmacokinets of Vitamin CAbsorption: Well absorbed orally.
Distribution: Widely distributed both extracellularly and intracellularly, It crosses the placenta and also distributed in to the breast milk.
Metabolism: Metabolized in the liver; partly oxidized in to active dehydroascorbic acid and inactive metabolites.
Excretion: Inactive metabolites and extra drug is excreted through urine.
Onset of Action for Vitamin CN/ADuration of Action for Vitamin CN/AHalf Life of Vitamin CN/ASide Effects of Vitamin C1. Discomfort at injection site
2. Acid urine
3. Renal calculi
Contra-indications of Vitamin CNo known contraindicationsSpecial Precautions while taking Vitamin C1. Renal impairment
2. Ingestion of large doses during pregnancy has resulted in scurvy in neonates
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationMay be usedIndications for Vitamin C1. Scurvy
2. Prophylaxis and treatment of vitamin C deficiency
3. As an antioxidant to maintain natural colour and flavour of food items
4. For acidification of urine
5. Capillary fragility
6. Dental caries
Interactions for Vitamin COral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions .
Warfarin: The anticoagulant effects of warfarin is reduced.
Lab Tests: Large doses (>500 mg) of vitamin C may cause false negative urine glucose determinations. May result in false negative amine dependent stool occult blood tests.Typical Dosage for Vitamin COral:
Adults: 50 to 1000mg/day depending up on the requirement.
Pregnancy and lactation: 100 to 150mg/day
Children: 30 to 100mg/day.
Adults: 1000mg twice daily to thrice daily.
Children: 300mg to 1000mg daily.
Sub clinical scurvy:
Oral, S.C., I.M., or I.V.: 100 to 250mg once daily or twice daily depending up on the severity of the condition. Then give a maintenance dosage of 50mg/day.
Children: 100 to 300mg depending up on the severity. Then give a maintenance dose of 35mg/day.
Schedule of Vitamin CC1 (Oral)
C (Parenteral)Storage Requirements for Vitamin CStore in a cool dry area in a well closed container. Protects from moisture, light and direct heat.Effects of Missed Dosage of Vitamin CTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin CDiscontinue the therapy and provide symptomatic and supportive measures.
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