Minoxidil Pharmacology

Minoxidil

About Minoxidil
A potassium channel agonist,Direct-Acting Vasodilator, Hair- growth stimulant,In androgenic alopecia.
Mechanism of Action of Minoxidil
Minoxidil works by activating PGHS 1 (prostaglandin endoperoxide synthase-1) which helps promote hair growth. It enhances follicular size and results in thicker hair shafts and stimulates and prolongs the anagen phase of the hair cycle. This will results in longer and increased number of hairs.
Pharmacokinets of Minoxidil
Absorption: It is poorly absorbed after topical administration
Onset of Action for Minoxidil
N/A
Duration of Action for Minoxidil
N/A
Half Life of Minoxidil
N/A
Side Effects of Minoxidil
1.Headache
2.Dizziness
3.Irritation
4.Itch
5.Contact dermatitis
6.Palpitation
7.Irregular heart beat
8.Nausea
9.Vomiting
10.Diarrhoea
11.Dermatitis
12.Chest pain
13.Hypertension
14.Hypotension
Contra-indications of Minoxidil
1.Hypersensitivity to Minoxidil
Special Precautions while taking Minoxidil
1.Renal impairment
2.Hepatic impairment
3.Cardiac impairment
4.Avoid contact with broken area, eye and mucus membrane
Pregnancy Related Information
Contraindicated.
Old Age Related Information
Use with caution
above 65 years: contraindicated
Breast Feeding Related Information
Contraindicated.
Children Related Information
Contraindicated
NEONATES: contraindicated
Indications for Minoxidil
1. Alopecia areata
2. Androgenic alopecia
Interactions for Minoxidil
N/A
Typical Dosage for Minoxidil
Topical
Adult: Apply 1 ml solution on the dry scalp and hair 2 times daily for 4 months or longer
Children: contraindicated
Schedule of Minoxidil
N/A
Storage Requirements for Minoxidil
Store at room temperature. Protect from heat and light. Keep out of the reach of children
Effects of Missed Dosage of Minoxidil
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Minoxidil
Give supportive measures and symptomatic treatment. Thoroughly wash the hair. In accidental ingestion drug can be removed from the body by inducing emesis or gastric lavage. Absorption of the drug can be reduced by administration of activated charcoal

Home Delivery for Minoxidil in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including minoxidil.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for minoxidil and other medicines and health products. Home delivery services for minoxidil may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take minoxidil only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for minoxidil before they complete the sale. You can get this information while placing the order for minoxidil with the pharmacy.

Minoxidil is a generic medicine name and there are several brands available for it. Some of the brands for minoxidil might be better known than minoxidil itself. If the pharmacy that's willing to deliver medicines to your home doesn't have minoxidil in stock, you can ask for one of the branded alternatives for minoxidil.